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Simultaneous Determination of Stable Carbon, Oxygen, and Hydrogen Isotopes in Cellulose

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Loader N.J., Street-Perrott F.A., Daley T.J., Hughes P.D.M., Kimak A., Levanič T., Mallon G., Mauquoy D., Robertson I., Roland T.P., van Bellen S., Ziehmer M.M., Leuenberger M.,
Project iTREE-Long-term variability of tree growth in a changing environment - identifying physiological mechanisms using stable C and O isotopes in tree rings.
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Original article (peer-reviewed)

Journal Analytical Chemistry
Volume (Issue) 87(1)
Page(s) 376 - 380
Title of proceedings Analytical Chemistry
DOI 10.1021/ac502557x


A technological development is described through which the stable carbon-, oxygen-, and nonexchangeable hydrogen-isotopic ratios (δ13C, δ18O, δ2H) are determined on a single carbohydrate (cellulose) sample with precision equivalent to conventional techniques (δ13C 0.15‰, δ18O 0.30‰, δ2H 3.0‰). This triple-isotope approach offers significant new research opportunities, most notably in physiology and medicine, isotope biogeochem- istry, forensic science, and palaeoclimatology, when isotopic analysis of a common sample is desirable or when sample material is limited.