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Carving axon arbors to fit: master directs one kinase at a time.

Type of publication Peer-reviewed
Publikationsform Review article (peer-reviewed)
Publication date 2013
Author Satoh Daisuke, Arber Silvia,
Project Entwicklung und Funktion von motorischen Netzwerken
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Review article (peer-reviewed)

Journal Cell
Volume (Issue) 153(7)
Page(s) 1425 - 1426
Title of proceedings Cell
DOI 10.1016/j.cell.2013.05.047

Open Access

URL http://www.cell.com/cell/abstract/S0092-8674(13)00653-3
Type of Open Access Publisher (Gold Open Access)

Abstract

Pyramidal neurons in the cortex require the master kinase LKB1 for early axon specification. Courchet et al. now uncover a later role for LKB1 and its tango with the downstream effector kinase NUAK1 in controlling terminal axonal branching through influencing mitochondrial motility in axons.
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