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Versatile coordination of acetazolamide to ruthenium( ii ) p -cymene complexes and preliminary cytotoxicity studies

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Biancalana Lorenzo, Batchelor Lucinda K., Ciancaleoni Gianluca, Zacchini Stefano, Pampaloni Guido, Dyson Paul J., Marchetti Fabio,
Project Modulation of the site specificity of binding of metal-based drugs to chromatin
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Original article (peer-reviewed)

Journal Dalton Transactions
Volume (Issue) 47(28)
Page(s) 9367 - 9384
Title of proceedings Dalton Transactions
DOI 10.1039/c8dt01555d

Open Access


The bioactive molecule acetazolamide was incorporated in Ru( ii )- p -cymene complexes with different coordination modes. Two of the resulting complexes were non cytotoxic towards A2780, A2780cisR and HEK-293 cell lines.