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Nystagmus and oscillopsia.

Type of publication Not peer-reviewed
Publikationsform Review article (non peer-reviewed)
Publication date 2011
Author Straube A., Bronstein A., Straumann D.,
Project Three-dimensional kinematical analysis of ocular motor disorders in humans
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Review article (non peer-reviewed)

Journal Eur J Neurol
Volume (Issue) 19(1)
Page(s) 6 - 14
Title of proceedings Eur J Neurol
DOI 10.1111/j.1468-1331.2011.03503.x

Open Access

Type of Open Access Repository (Green Open Access)


The ocular motor system consists of several subsystems, including the vestibular ocular nystagmus saccade system, the pursuit system, the fixation and gaze-holding system and the vergence system. All these subsystems aid the stabilization of the images on the retina during eye and head movements and any kind of disturbance of one of the systems can cause instability of the eyes (e.g. nystagmus) or an inadequate eye movement causing a mismatch between head and eye movement (e.g. bilateral vestibular failure). In both situations, the subjects experience a movement of the world (oscillopsia) which is quite disturbing. New insights into the patho-physiology of some of the ocular motor disorders have helped to establish new treatment options, in particular in downbeat nystagmus, upbeat nystagmus, periodic alternating nystagmus, acquired pendular nystagmus and paroxysmal vestibular episodes/attacks. The discussed patho-physiology of these disorders and the current literature on treatment options are discussed and practical treatment recommendations are given in the paper.