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Supramolecular Agent-Simulant Correlations for the Luminescence Based Detection of V-Series Chemical Warfare Agents with Trivalent Lanthanide Complexes

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Dennison Genevieve H., Bochet Christian G., Curty Christophe, Ducry Julien, Nielsen David J., Sambrook Mark R., Zaugg Andreas, Johnston Martin R.,
Project Photons in organic synthesis
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Original article (peer-reviewed)

Journal European Journal of Inorganic Chemistry
Volume (Issue) 2016(9)
Page(s) 1348 - 1358
Title of proceedings European Journal of Inorganic Chemistry
DOI 10.1002/ejic.201600105

Abstract

Soln. spectroscopic studies into the interactions of eight potential bidentate V-series organophosphorus chem. warfare agent (OP CWA) simulants with [Eu(phen)2(NO3)3]·2H2O demonstrated that the chem. and structural compn. of the secondary binding site within the simulant was of paramount importance.  Only simulants contg. both phosphoryl/phosphonyl and amine moieties generated analogous spectroscopic behaviors to V-series OP CWAs seen in previous studies.  The bidentate chelation mechanism was driven by the phosphoryl/phosphonyl moieties and that the presence of the amine moieties induced a significant secondary dynamic luminescence quenching mechanism.  The binding modes of the simulants VO and TEEP to trivalent lanthanides (Eu and La) were further studied using 1H and 31P NMR spectroscopic titrns. and kinetic IR expts.  VO, with both the phosphonyl and amine binding sites is the most appropriate simulant for V-series OP CWAs in supramol. studies with trivalent lanthanide ions and the authors recommend VO for use in supramol. studies of this type.
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