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Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?

Type of publication Peer-reviewed
Publikationsform Review article (peer-reviewed)
Publication date 2015
Author Herrmann Ing, Schlegel Andrea, Graf Rolf, Stark Wendelin, Beck-Schimmer Beatrice,
Project Metal Nanomagnets for Medicine - Towards Single Cell Surgery
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Review article (peer-reviewed)

Journal J Nanobiotechnology
Volume (Issue) 13
Page(s) 49
Title of proceedings J Nanobiotechnology
DOI 10.1186/s12951-015-0110-8


Recent studies report promising results regarding extracorporeal magnetic separation-based blood purification for the rapid and selective removal of disease-causing compounds from whole blood. High molecular weight compounds, bacteria and cells can be eliminated from blood within minutes, hence offering novel treatment strategies for the management of intoxications and blood stream infections. However, risks associated with incomplete particle separation and the biological consequences of particles entering circulation remain largely unclear. This article discusses the promising future of magnetic separation-based purification while keeping important safety considerations in mind.