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Raspberry-Pi Based System for Propofol Monitoring

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Francesca Stradolini, Tuoheti Abuduwaili, Tugba Kilic, Danilo Demarchi, Sandro Carrara,
Project Continuous Monitoring of Anesthetics Concentration to Control Anesthesia Delivery (acronym: CoMofA)
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Original article (peer-reviewed)

Journal Integration, the VLSI Journal
Page(s) 2018
Title of proceedings Integration, the VLSI Journal

Abstract

Induction of anesthesia with propofol is a largely adopted technique in hospital environments. The correct dosage of this compound is essential to avoid under- or over-anesthesia that may result in serious side-effects. Therefore, in clinical settings, long-term monitoring of propofol is of great importance. To this aim, in this work, we present the design and the validation of a custom-made, low-cost and portable Point-of-Care (PoC) system based on electrochemical detection for propofol monitoring. Fouling phenomenon due to phenolic oxidation of propofol has been overcome by adopting a Pencil Graphite Electrode (PGE) 3H as sensor. The validation of the system focused on testing the measurement speed through scan-rate analysis, which is important due to the fast clearance of propofol ; and interference study with Paracetamol (APAP), since it is an analgesic compound frequently administered with propofol in medical practices.
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