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Metabolic stability of cells for extended metabolomical measurements using NMR. A comparison between lysed and additionally heat inactivated cells

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Diserens G., Hertig D., Vermathen M., Legeza B., Flück C. E., Nuoffer J.M., Vermathen P.,
Project Amino acid conjugated Photosensitizers in biocompatible nanoparticles and their interactions with Cellular Environments studied by High Resolution Liquid and Magic Angle Spinning (HR-MAS) NMR Spectroscopy
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Original article (peer-reviewed)

Journal The Analyst
Volume (Issue) 142(3)
Page(s) 465 - 471
Title of proceedings The Analyst
DOI 10.1039/c6an02195f

Abstract

For extended HR-MAS NMR measurements, cell lysis in combination with heat inactivation minimizes metabolite concentration modifications over the measurement time.
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