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Vaccines for Invasive Fungal Infections

Type of publication Peer-reviewed
Publikationsform Book (peer-reviewed)
Author Khanna Nina, Stuehler Claudia,
Project Relevance of different CD4+ T-cell subsets for antifungal defense. What is aberrant in immunocompromised patients?
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Book (peer-reviewed)

Publisher Springer New York, New York NY
ISBN 978-1-4939-7103-9
DOI 10.1007/978-1-4939-7104-6_20


Human invasive fungal infections are caused by different mold and yeast species. Hence, cross-reactive T cells that recognize conserved epitopes of various fungal pathogens are of special interest for vaccination protocols or adoptive T cell transfer. Here, we describe an ELISpot-based method to test cross-reactivity of T cell lines or clones to different molds and yeasts.