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Early Neolithic genomes from the eastern Fertile Crescent

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Broushaki Farnaz, Thomas Mark G., Link Vivian, Lopez Saioa, van Dorp Lucy, Kirsanow Karola, Hofmanova Zuzana, Diekmann Yoan, Cassidy Lara M., Diez-del-Molino David, Kousathanas Athanasios, Sell Christian, Robson Harry K., Martiniano Rui, Bloecher Jens, Scheu Amelie, Kreutzer Susanne, Bollongino Ruth, Bobo Dean, Davoudi Hossein, Munoz Olivia, Currat Mathias, Abdi Kamyar, Biglari Fereidoun, Craig Oliver E., Bradley Daniel G., Shennan Stephen, Veeramah Krishna R., Mashkour Marjan, Wegmann Daniel, Hellenthal Garrett, Burger Joachim,
Project Reconstructing Europeans' genetic evolution through computer simulations and heterochronous molecular data
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Original article (peer-reviewed)

Page(s) 499 - 503
Title of proceedings SCIENCE
DOI 10.1126/science.aaf7943

Open Access

Type of Open Access Publisher (Gold Open Access)


We sequenced Early Neolithic genomes from the Zagros region of Iran (eastern Fertile Crescent), where some of the earliest evidence for farming is found, and identify a previously uncharacterized population that is neither ancestral to the first European farmers nor has contributed significantly to the ancestry of modern Europeans. These people are estimated to have separated from Early Neolithic farmers in Anatolia some 46-77,000 years ago and show affinities to modern day Pakistani and Afghan populations, but particularly to Iranian Zoroastrians. We conclude that multiple, genetically differentiated hunter-gatherer populations adopted farming in SW-Asia, that components of pre-Neolithic population structure were preserved as farming spread into neighboring regions, and that the Zagros region was the cradle of eastward expansion.