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SPLATCHE3: simulation of serial genetic data under spatially explicit evolutionary scenarios including long-distance dispersal

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Currat Mathias, Arenas Miguel, Quilodràn Claudio S, Excoffier Laurent, Ray Nicolas,
Project Reconstructing Europeans' genetic evolution through computer simulations and heterochronous molecular data
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Original article (peer-reviewed)

Journal Bioinformatics
Volume (Issue) 35(21)
Page(s) 4480 - 4483
Title of proceedings Bioinformatics
DOI 10.1093/bioinformatics/btz311

Open Access

URL http://doi.org/10.1093/bioinformatics/btz311
Type of Open Access Publisher (Gold Open Access)

Abstract

SPLATCHE3 simulates genetic data under a variety of spatially explicit evolutionary scenarios, extending previous versions of the framework. The new capabilities include long-distance migration, spatially and temporally heterogeneous short-scale migrations, alternative hybridization models, simulation of serial samples of genetic data and a large variety of DNA mutation models. These implementations have been applied independently to various studies, but grouped together in the current version.Availability and implementationSPLATCHE3 is written in C++ and is freely available for non-commercial use from the website http://www.splatche.com/splatche3. It includes console versions for Linux, MacOs and Windows and a user-friendly GUI for Windows, as well as detailed documentation and ready-to-use examples.
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