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Disseminated rhinovirus C8 infection with infectious virus in blood and fatal outcome in a child with repeated episodes of bronchiolitis.

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Lupo Julien, Schuffenecker Isabelle, Morel-Baccard Christine, Bardet Julie, Payen Valérie, Kaiser Laurent, Constant Samuel, Lobrinus Johannes Alexander, Lin-Marq Nathalie, Lina Bruno, Morand Patrice, Tapparel Caroline, Lupo Julien, Schuffenecker Isabelle, Morel-Baccard Christine, Bardet Julie, Payen Valérie, Kaiser Laurent, Constant Samuel, Lobrinus Johannes Alexander, Lin-Marq Nathalie, Lina Bruno, Morand Patrice, Tapparel Caroline,
Project Rhinovirus et entérovirus: déterminants génomiques et phénotypes associés
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Original article (peer-reviewed)

Journal Journal of clinical microbiology
Volume (Issue) 53(5)
Page(s) 1775 - 7
Title of proceedings Journal of clinical microbiology
DOI 10.1128/jcm.03484-14

Abstract

We report a fatal case of acute lower respiratory tract disease with human rhinovirus C (HRV-C) as the unique cause in a 19-month-old girl with a history of repeated episodes of bronchiolitis. HRV-C type 8 nucleic acids were observed in respiratory, stool, and cerebrospinal fluid samples, and infectious virions were isolated from patient serum after inoculation onto reconstituted airway epithelia.
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