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X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Roethlisberger P, Istrate A., Marcaida Lopez M. J., Visini R., Stocker A., Reymond J.-L., Leumann C. J.,
Project A Chemical Space Approach to Bioactive Peptides
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Original article (peer-reviewed)

Journal Chemical Communications
Volume (Issue) 52(26)
Page(s) 4749 - 4752
Title of proceedings Chemical Communications
DOI 10.1039/c6cc00374e

Open Access


DNA duplexes containing unnatural base-pair surrogates are attractive biomolecular nanomaterials with potentially beneficial photophysical or electronic properties. Herein we report the first X-ray structure of a duplex containing a phen-pair in the center of the double helix in a zipper like stacking arrangement.