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A re-examination of the time constant of the oculomotor neural integrator in human.

Type of publication Not peer-reviewed
Publikationsform Original article (non peer-reviewed)
Publication date 2012
Author Khojasteh Elham, Bockisch Christopher J, Straumann Dominik, Hegemann Stefan C A,
Project Three-dimensional kinematical analysis of ocular motor disorders in humans
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Original article (non peer-reviewed)

Journal Conf Proc IEEE Eng Med Biol Soc
Page(s) 4780 - 3
Title of proceedings Conf Proc IEEE Eng Med Biol Soc


We studied the horizontal oculomotor neural integrator in healthy human subjects during gaze holding in darkness. We found large variability among subjects with respect to the estimated time constants and the integrator's null position. We also found that individual subjects could demonstrate significantly nonlinear drift velocities as a function of eye position. Nevertheless, a consistent trend did not emerge. Consequently, cross subject averaging eliminates idiosyncratic nonlinear patterns and the average can be approximated by a linear function inside the range that was tested