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Planar Block Copolymer Membranes by Vesicle Spreading

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Publication date 2011
Author Dorn J., Belegrinou S., Kreiter M., Sinner E. K., Meier W.,
Project Nanostructured Polymers
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Original article (peer-reviewed)

Journal Macromolecular Bioscience
Volume (Issue) 11(5)
Page(s) 514 - 525
Title of proceedings Macromolecular Bioscience
DOI 10.1002/mabi.201000396

Open Access

Abstract

An easy route to planar solid-supported polymer membranes by vesicle spreading is described. Pre-organized PB-PEO assemblies were spread on two different supports, i.e. strongly hydrophilic glass surfaces and ultrasmooth gold substrates. Polymer membranes were produced on a hydrophilic support by spreading hydroxyl-functionalized polymer vesicles, while covalently immobilized polymer membranes were obtained by spreading LA-functionalized polymer vesicles on gold substrates. Covalently bound membranes were further incubated with the peptide polymyxin B. Interactions with the polymer membrane were detected by EIS. These systems are of great interest to fundamental membrane science and have potential in technological applications, such as drug screening and (bio)sensing.
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