plant-pathogen interaction; barley; Lr34; sorghum; rice; broad-spectrum disease resistance
Singla J, Luethi L, Wicker T, Bansal U, Krattinger SG, Keller B (2017), Characterization of Lr75: a partial, broad-spectrum leaf rust resistance gene, in Theoretical and Applied Genetics
, 130, 1-12.
Bucher R., Veyel D., Willmitzer L., Krattinger S.G., Keller B, Bigler L. (2017), Combined GC- and UHPLC-HR-MS based metabolomics to analyze durable anti-fungal resistance processes in cereals, in Chimia
, 71, 156-159.
Keller B., Krattinger S.G. (2017), Genomic compartments in barley, in Nature
, 544, 424-425.
Yang P., Herren G., Krattinger S.G., Keller B. (2017), Large-scale maize seedling infection with Exserohilum turcicum in the greenhouse, in Bio-Protocol
, 7, e2567.
Boni R., Chauhan H., Hensel G., Roulin A., Sucher J., Kumlehn J., Brunner S., Krattinger S.G., Keller B. (2017), Pathogen-inducible Ta-Lr34res expression in heterologous barley confers disease resistance without negative pleiotropic effects, in Plant Biotechnology Journal
, DOI: 10.11.
Thind A.K., Wicker T., Simkova H., Fossati D., Moullet O., Brabant C., Vrana J., Dolezel J., Krattinger S.G. (2017), Rapid cloning of genes in hexaploid wheat using cultivar-specific long-range chromosome assembly, in Nature Biotechnology
, 35, 793-796.
Thind A.K., Wicker T., Krattinger S.G. (2017), Rapid identification of rust resistance genes through cultivar-specific de novo chromosome assemblies, in Periyannan S. (ed.), 245-255.
Krattinger S.G., Keller B. (2017), Resistance: Double gain with one gene, in Nature Plants
, 3, 17019.
Sucher J, Boni R, Yang P, Rogowsky P, Buechner H., Kastner C., Kumlehn J., Krattinger SG, Keller B (2017), The durable wheat disease resistance gene Lr34 confers common rust and northern corn leaf blight resistance in maize, in Plant Biotechnology Journal
, 15, 489-496.
Rinaldo A., Gilbert B., Boni R., Krattinger S.G., Singh D., Park R.F., Lagudah E.S., Ayliffe M. (2017), The Lr34 adult plant rust resistance gene provides seedling resistance in durum wheat without senescence, in Plant Biotechnology Journal
, 15, 894-905.
Schnippenkoetter W., Lo C., Liu G., Dibley K., Chan W.L., White J., Milne R., Zwart A., Kwong E., Keller B., Godwin I., Krattinger S.G., Lagudah E.G. (2017), The wheat Lr34 multi-pathogen resistance gene confers resistance to anthracnose and rust in sorghum, in Plant Biotechnology Journal
, 15, 1387-1396.
Sucher J., Menardo F., Praz C., Boni R., Krattinger S.G., Keller B. (2017), Transcriptional profiling reveals no response of fungal pathogens to the durable, quantitative Lr34 disease resistance gene of wheat, in Plant Pathology
, DOI: 10.11.
Muller T., Schierscher-Viret B., Fossati D., Brabant C., Schori A., Keller B., Krattinger S.G. (2017), Unlocking the diversity of genebanks: whole-genome marker analysis of Swiss bread wheat and spelt, in Theoretical and Applied Genetics
, DOI 10.100.
Singla J, Krattinger SG (2016), Biotic stress resistance genes in wheat, in Wrigley CW (ed.), Academic Press, Oxford, UK, 388-392.
Krattinger SG, Keller B (2016), Molecular genetics and evolution of disease resistance in cereals, in New Phytologist
, 212, 320-332.
Sanchez-Martin. J, Steuernagel B, Ghosh S, Herren G, Hurni S, Adamski N, Vran J, Kubalakova M, Krattinger SG, Wicker T, Dolezel J, Keller B, Wulff BBH (2016), Rapid gene isolation in barley and wheat by mutant chromosome sequencing, in Genome Biology
, 17, 221.
Krattinger Simon, Sucher Justine, Selter Liselotte, Chauhan Harsh, Zhou Bo, Tang Mingzhi, Upadhyaya Narayana, Mieulet Delphine, Guiderdoni Emmanuel, Weidenbach Denise, Schaffrath Ulrich, Lagudah Evans, Keller Beat (2016), The wheat durable, multi-pathogen resistance gene Lr34 confers partial blast resistance in rice, in Plant Biotechnology Journal
, 14, 1261-1268.
Krattinger Simon, Keller Beat (2016), Trapping the intruder – Immune receptor domain fusions provide new molecular leads for improving disease resistance in plants, in Genome Biology
Chauhan H., Boni R., Bucher R., Kuhn B., Buchmann G., Sucher J., Selter L.L., Hensel G., Kumlehn J., Bigler L., Glauser G., Wicker T., Krattinger S.G., Keller B. (2015), The wheat resistance gene Lr34 results in the constitutive induction of multiple defense pathways in transgenic barley, in Plant Journal
, 84, 202-214.
Fungal plant diseases are a threat to crop production worldwide. Epidemics caused by fungal pathogens frequently result in crop failure. Plants on the other hand have evolved sophisticated strategies to cope with pathogen attacks. In wheat, more than 300 genes that confer resistance against pathogenic fungi have been described. Most of these genes however provide only short-lived protection and they are frequently overcome in the field due to rapid pathogen evolution. Only a few resistance genes have been identified so far that provide durable and broad-spectrum resistance. Although an indispensable source for breeding, this type of disease resistance is only poorly understood on the molecular level and only very few broad-spectrum disease resistance genes have been cloned in cereals until today. This project aims to understand durable and broad-spectrum disease resistance in cereals. The work focuses on two genes of wheat, Lr34 and Lr22a, that confer race non-specific resistance against fungal diseases in wheat.