Institute

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Name

Institut für Pharmakologie Medizinische Fakultät Universität Bern

Address Institut für Pharmakologie Medizinische Fakultät Universität Bern
Inselspital, INO-F
3010
CH-Bern
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Projects

Responsible applicant Institution of higher education Start End date Funding scheme

Structural and pharmacological properties of neuronal nicotinic acetylcholine receptors of mammalian autonomic ganglion neurones
Cachelin Armand University of Berne - BE 01.10.1991 31.12.1994 Project funding (Div. I-III)

Ion channel and receptor expression, distribution and func- tion during cell development
Reuter Harald University of Berne - BE 01.04.1988 31.03.1991 Project funding (Div. I-III)

Molecular mechanisms of neutrophil extracellular trap (NET) formation
Yousefi Shida University of Berne - BE 01.05.2017 30.04.2022 Project funding (Div. I-III)

Effects of drugs on anion permeability in erythrocytes
Fuhrmann Günter-Fred University of Berne - BE 01.10.1976 30.09.1977 Project funding (Div. I-III)

Regulation, Molecular Functions and Pathophysiological Relevance of BOK
Kaufmann Thomas University of Berne - BE 01.11.2021 31.10.2025 Project funding (Div. I-III)

Molecular basis and pharmacological modulation of calmodulin- mediated gating in voltage-dependent L-type calcium channels
Zühlke Roger D. University of Berne - BE 01.10.1999 30.09.2001 Project funding (Div. I-III)

Molecular mechanisms of neutrophil activation
Yousefi Shida University of Berne - BE 01.10.2002 31.03.2006 Project funding (Div. I-III)

Spektroskopische Datenbank
Clerc Jean University of Berne - BE 01.04.1978 31.03.1980 Project funding (Div. I-III)

Factors governing the pharmacokinetics and distribution of lipophilic drugs and environmental pollutants
Bickel Marcel H. University of Berne - BE 01.10.1981 30.09.1984 Project funding (Div. I-III)

Immunological characterization and regulation of Ca- transport systems in exitable tissues
Porzig Hartmut University of Berne - BE 01.10.1985 30.09.1988 Project funding (Div. I-III)

Biochemie und Biophysik des mitochondrialen Energie- stoffwechsels
Stucki Jörg University of Berne - BE 01.04.1980 31.03.1982 Project funding (Div. I-III)

Siglec-9 - A Novel Immunoregulatory Receptor
von Gunten Stephan University of Berne - BE 01.04.2011 30.09.2014 Project funding (Div. I-III)

Chaotic dynamics in neurons
Stucki Jörg University of Berne - BE 01.04.1997 31.03.2002 Project funding (Div. I-III)

EpCAM-specific designed ankyrin repeat proteins as ligands for tumor-targeted therapy with rationally engineered biotoxins
Zangemeister-Wittke Uwe University of Berne - BE 01.04.2008 30.09.2011 Project funding (Div. I-III)

Characterization of human lymphocytes expressing Siglec-9 in health and disease
Jandus Camilla University of Berne - BE 01.04.2010 31.03.2012 Marie Heim-Voegtlin grants

Biochemical and immunological characterization of Ca-trans- port mechanisms in excitable membranes
Porzig Hartmut University of Berne - BE 01.10.1984 30.09.1985 Project funding (Div. I-III)

Tagung des "EUROPEAN RED CELL CLUB"
Schatzmann Hans-Jürg University of Berne - BE 01.01.1982 30.06.1982 Scientific Conferences

Engineering Designed Ankyrin Repeat Protein-drug conjugates with optimized pharmacokinetics and payload number for tumor targeting
Zangemeister-Wittke Uwe University of Berne - BE 01.01.2017 31.12.2019 Project funding (Div. I-III)

GABA-A receptor isoforms: architecture and ligand binding sites
Sigel Erwin University of Berne - BE 01.10.2001 30.09.2004 Project funding (Div. I-III)

Regulation of sphingosine kinases-1 and -2 in renal cells and contribution to chronic inflammatory kidney diseases.
Huwiler Andrea University of Berne - BE 01.10.2014 31.12.2017 Project funding (Div. I-III)

Hormonale Steuerung von Zellvorgängen in Fettzellen und Blutplättchen
Bally Peter University of Berne - BE 01.07.1976 31.03.1978 Project funding (Div. I-III)

G-alpha-16-dependent signal transduction and induction of differentiation on hematopoietic cells
Baltensperger Kurt University of Berne - BE 01.10.2000 31.03.2004 Project funding (Div. I-III)

Regulation of sphingosine kinases-1 and -2 in renal cells and contribution to inflammatory kidney diseases
Huwiler Andrea University of Berne - BE 01.06.2006 30.09.2010 Project funding (Div. I-III)

Molecular pathways regulating eosinophil numbers and functions
Simon Hans-Uwe University of Berne - BE 01.05.2019 30.04.2023 Project funding (Div. I-III)

Kinetische Untersuchungen an Trägertransporten der Erythrozytenmembran
Reuter Harald University of Berne - BE 01.04.1978 31.03.1980 Project funding (Div. I-III)

Binding Processes as Determinants of Distribution and Pharmacokinetics of Lipophilic Drugs
Bickel Marcel H. University of Berne - BE 01.10.1978 30.09.1981 Project funding (Div. I-III)

Signal transduction in neurites and growth cones during neuronal development
Reber Bernhard University of Berne - BE 01.04.1998 31.03.2001 Project funding (Div. I-III)

Effects of antidepressants and related drugs on phospholipid composition and membrane protein functions of cultured human cells
Honegger Ulrich University of Berne - BE 01.10.1985 30.09.1987 Project funding (Div. I-III)

Molecular mechanisms of granulocyte activation
Yousefi Shida University of Berne - BE 01.04.2006 30.09.2009 Project funding (Div. I-III)

Intra- und extracelluläre Bindungs- und Trans- lokationsprozesse körperfremder Verbindungen
Bickel Marcel H. University of Berne - BE 01.10.1976 30.09.1978 Project funding (Div. I-III)

Biochemie und Biophysik des mitochondrialen Energiestoff- wechsels.
Stucki Jörg University of Berne - BE 01.04.1982 31.03.1985 Project funding (Div. I-III)

Role of autophagy in granulocyte survival and differentiation
Simon Hans-Uwe University of Berne - BE 01.04.2010 31.03.2013 Project funding (Div. I-III)

Sweet control: Sialoglycans in cell-mediated anti-tumor responses
von Gunten Stephan University of Berne - BE 01.04.2019 31.03.2023 Project funding (Div. I-III)

Factors governing the pharmacokinetics and distribution of lipophilic drugs and environmental pollutants
Bickel Marcel H. University of Berne - BE 01.10.1984 30.09.1987 Project funding (Div. I-III)

Influence of vitamin E on in vivo- and in vitro-effects of cationic-amphiphilic drugs.
Honegger Ulrich University of Berne - BE 01.10.1996 30.09.2000 Project funding (Div. I-III)

Optimierung des Energiestoffwechsels
Stucki Jörg University of Berne - BE 01.04.1985 31.03.1988 Project funding (Div. I-III)

Molecular mechanisms of extracellular DNA trap formation by granulocytes
Yousefi Shida University of Berne - BE 01.04.2013 31.03.2016 Project funding (Div. I-III)

Role of neutrophil and eosinophil apoptosis in inflammatory responses
Simon Hans-Uwe University of Berne - BE 01.04.2005 31.03.2010 Project funding (Div. I-III)

Effects of antidepressants and related drugs on phospholipid composition and membrane protein functions of cultured human cells
Honegger Ulrich University of Berne - BE 01.10.1987 30.09.1990 Project funding (Div. I-III)

Role of autophagy in inflammation and cancer
Simon Hans-Uwe University of Berne - BE 01.04.2016 31.03.2019 Project funding (Div. I-III)

Exploring requirements for the maintenance of oncogenic KRAS-induced lung and pancreatic tumors
Konstantinidou Georgia University of Berne - BE 01.08.2016 31.07.2020 SNSF Professorships

Molecular mechanisms of granulocyte activation
Yousefi Shida University of Berne - BE 01.11.2009 31.03.2013 Project funding (Div. I-III)

Characterizing Biochemical Networks: Cycle Analysis, Redundancy and Input-Output Path
Wagner Clemens University of Berne - BE 01.10.2003 31.03.2005 Project funding (Div. I-III)

Einfluss der Fluidität der Erythrozytenmembran auf Trägersysteme verschiedener Transporte
Wilbrandt Walter University of Berne - BE 01.01.1976 31.03.1978 Project funding (Div. I-III)

Vitamin E reduces cumulative drug uptake and phospholipidosis in cultured human cells. Study on the mode of action
Honegger Ulrich University of Berne - BE 01.10.1991 30.09.1996 Project funding (Div. I-III)

Hormon-induzierte Ca-Oszillationen und zelluläre Bioenergetik in Hepatocyten
Stucki Jörg University of Berne - BE 01.04.1991 31.03.1994 Project funding (Div. I-III)

The role of G proteins ans second messengers in regulation the differentiation of erythroid progenitor cells
Porzig Hartmut University of Berne - BE 01.04.1991 31.03.1994 Project funding (Div. I-III)

Isolation and immunological characterization of the Na-Ca- exchange protein from myocardial membranes
Porzig Hartmut University of Berne - BE 01.10.1988 30.09.1991 Project funding (Div. I-III)

Design of modified immunoglobuin preparations with additionally induced polyspecificity for passive immunotherapy of sepsis
von Gunten Stephan University of Berne - BE 01.11.2012 30.04.2016 Bulgarian-Swiss Research Programme (BSRP)

Identifying binding partners and molecular functions of the Bcl-2 family member bok
Kaufmann Thomas University of Berne - BE 01.02.2014 31.03.2017 Project funding (Div. I-III)

Role of autophagy in inflammation and cancer
Simon Hans-Uwe University of Berne - BE 01.04.2013 31.03.2016 Project funding (Div. I-III)

Unters. über Regulationsmechanismen der Kationen- Permeabilitäten u.- Transporte v. Herz- u. Erythro- zytenmembranen
Reuter Harald University of Berne - BE 01.04.1976 31.03.1979 Project funding (Div. I-III)

Factors governing the pharmacokinetics and adipose tissue storage of lipophilic drugs and environmental pollutants.
Bickel Marcel H. University of Berne - BE 01.10.1987 30.09.1990 Project funding (Div. I-III)

Expression, localization and function of ion channels and intracellular calcium stores in neuronal cells during differentiation
Reuter Harald University of Berne - BE 01.04.1991 31.03.1996 Project funding (Div. I-III)

SSMBS Jahreskredit 2004
Schweizerische Stiftung für medizinisch-biologische Stipendien Institution abroad - IACH 01.01.2004 31.12.2004 SFGBM Fellowships for advanced researchers

Biochemie und Biophysik des mitochondrialen Energiestoff- wechsels und des Ionentransports an erregbaren Membranen
Stucki Jörg University of Berne - BE 01.04.1978 31.03.1980 Project funding (Div. I-III)

Molekulare Wirkungsmechanismen von Calcium-Antagonisten
Höltje Hans-Dieter University of Berne - BE 01.01.1986 31.03.1987 Project funding (Div. I-III)

Exploring the role of Siglec-7 and -9 in immunity
von Gunten Stephan University of Berne - BE 01.10.2015 30.09.2018 Project funding (Div. I-III)

Tumor-targeting of therapeutic oligonucleotides with DARPins (D-A-CH/LAE)
Zangemeister-Wittke Uwe University of Berne - BE 01.09.2010 31.08.2014 Project funding (Div. I-III)

The GABA-A receptors: Application of subunit concatenation and benzodiazepine binding site
Sigel Erwin University of Berne - BE 01.10.2004 30.09.2010 Project funding (Div. I-III)

Outer mitochondrial membrane and chloroplast envelope
Stucki Jörg University of Berne - BE 01.11.1985 30.04.1986 Scientific Conferences

Molecular Functions and Pathophysiological Relevance of BOK
Kaufmann Thomas University of Berne - BE 01.05.2017 31.10.2021 Project funding (Div. I-III)

Effects of desipramine on beta-adrenergic receptors and phospholipid metabolism in cultured human fibroblasts
Honegger Ulrich University of Berne - BE 01.10.1981 30.09.1983 Project funding (Div. I-III)

Hormonale Steuerung von Zellvorgängen
Bally Peter University of Berne - BE 01.04.1978 30.09.1982 Project funding (Div. I-III)

Mechanisms involved in the regulation of ion channels and of neurotransmitter receptors in excitable and non-excitable membranes.
Reuter Harald University of Berne - BE 01.04.1982 31.03.1985 Project funding (Div. I-III)

Optimierung des Energiestoffwechsels
Stucki Jörg University of Berne - BE 01.04.1988 31.03.1991 Project funding (Div. I-III)

The GABA-A receptor: associated proteins and human polymorphisms
Sigel Erwin University of Berne - BE 01.10.1998 30.09.2001 Project funding (Div. I-III)

Workshop of the International Study Group for Biothermokinetics
Stucki Jörg University of Berne - BE 01.07.1982 31.12.1982 Scientific Conferences

Survival and proliferation of small cell lung cancer cells by Fas and TRAIL receptor activation - Molecular mechanisms and clinical implications
Zangemeister-Wittke Uwe University of Zurich - ZH 01.04.2004 31.03.2008 Project funding (Div. I-III)

Signal transduction in neurites and growth cones in neuronal development
Reber Bernhard University of Berne - BE 01.10.1994 31.12.1998 Project funding (Div. I-III)

The GABA-A receptor channel: Functional architecture, localiza- tion at specific membrane domains, and modulation
Sigel Erwin University of Berne - BE 01.10.1990 30.09.1993 Project funding (Div. I-III)

Regulation of Cell Death and Innate Immune Signalling in Granulocytes
Kaufmann Thomas University of Berne - BE 01.02.2014 30.06.2017 Project funding (Div. I-III)

Effects of desipramine on ß-adrenergic receptors and phos- pholipid metabolism in cultured human fibroblasts.
Honegger Ulrich University of Berne - BE 01.10.1983 30.09.1985 Project funding (Div. I-III)

Factors governing the pharmacokinetics and adipose tissue storage of lipophilic drugs and environmental pollutants
Bickel Marcel H. University of Berne - BE 01.10.1990 31.03.1993 Project funding (Div. I-III)

Hormon-induzierte Ca-Oszillationen und zelluläre Bioenergetik in Hepatocyten
Stucki Jörg University of Berne - BE 01.04.1994 31.03.1997 Project funding (Div. I-III)

Exploring the Potential of the Novel Triterpenoid AMR-Me for Breast Cancer Therapy
Thangaiyan Rabi University of Berne - BE 01.05.2010 31.07.2010 International short research visits

Molecular properties and regulation of ion channels and receptors and their involvement in cell function
Reuter Harald University of Berne - BE 01.04.1985 31.03.1988 Project funding (Div. I-III)

Molecular Mechanisms and Immunopathology of Apoptotic Signalling Pathways in Liver and Innate Immune Cells
Kaufmann Thomas University of Berne - BE 01.05.2012 31.08.2013 SNSF Professorships

Regulation of sphingosine kinases-1 and -2 in renal cells and contribution to chronic inflammatory kidney diseases.
Huwiler Andrea University of Berne - BE 01.04.2011 30.09.2014 Project funding (Div. I-III)

Link between desensitization and phosphorylation of the ni- cotinic acetylcholine receptor at the frog neuromuscular junction
Cachelin Armand University of Berne - BE 01.10.1986 30.09.1988 Project funding (Div. I-III)

The role of G protein expression and function in growth factor- regulated development of normal and leukemic erythroid progenitorcells
Porzig Hartmut University of Berne - BE 01.04.1994 30.09.1999 Project funding (Div. I-III)

Role of eosinophil and neutrophil apoptosis in allergic and non- allergic inflammatory responses
Simon Hans-Uwe University of Berne - BE 01.04.2000 31.03.2005 Project funding (Div. I-III)

GABA-A receptor channels: Biosynthesis, subunit stoichiometry andarangement, and cytoskeletal anchoring
Sigel Erwin University of Berne - BE 01.10.1993 30.09.1998 Project funding (Div. I-III)
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