Institute

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Name

Abteilung Strukturbiologie und Biophysik Biozentrum Universität Basel

Address Abteilung Strukturbiologie und Biophysik Biozentrum Universität Basel
Spitalstrasse 41
4056
CH-Basel
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Projects

Responsible applicant Institution of higher education Start End date Funding scheme

Protein homology modeling and bioinformatics approaches to the structural basis of inherited disease
Schwede Torsten University of Basel - BS 01.10.2002 30.09.2006 Project funding

Structural studies of insect allergens
Markovic-Housley Zora University of Basel - BS 01.04.2007 31.03.2013 Project funding

Structure, dynamics and function of CCR5-arrestin interactions
Grzesiek Stephan University of Basel - BS 01.05.2021 30.04.2024 India

Determination of the Crystal Structure of adenovirus type 2 hexon; crystallization characterizations of other proteins
Burnett Roger M. University of Basel - BS 01.10.1977 30.09.1980 Project funding

Studies on the molecular biology of the intracellular transport of immunoglobulins
Franklin Richard University of Basel - BS 01.07.1985 30.06.1988 Project funding

Purchase of a 900 MHz high-resolution NMR instrument
Grzesiek Stephan University of Basel - BS 01.12.2013 30.11.2014 R'EQUIP

Verzweigte Membranen als System zum Studium von Ionophoren
Schindler Hansgeorg University of Basel - BS 01.01.1977 31.12.1978 Project funding

Structural determinants of chaperone function
Hiller Sebastian University of Basel - BS 01.08.2016 31.07.2019 Project funding

Elucidating allosteric signal transmission in the beta1-adrenergic receptor
Isogai Shin University of Basel - BS 01.04.2017 31.08.2019 Ambizione

Isolierung und molekularbiologische Eigenschaften von Dopaminrezeptoren des Zentralnervensystems
Franklin Richard University of Basel - BS 01.10.1976 30.09.1979 Project funding

Functional dry cavities in proteins
Abiko Layara Akemi University of Basel - BS 01.10.2020 30.09.2021 Spark

Molecular mechanisms of c-di-GMP signaling
Schirmer Tilman University of Basel - BS 01.04.2016 31.03.2020 Project funding

Mechanistic dynamics of the chaperone network in the endoplasmatic reticulum
Hiller Sebastian University of Basel - BS 01.08.2022 31.07.2026 Project funding

Structure and Dynamics of the Escherichia Coli transcription termination factor Rho
Burmann Björn University of Basel - BS 01.10.2013 30.09.2016 Ambizione

Conformational dynamics of ATP-driven molecular machines: single molecule FRET studies of helicases and topoisomerases
Klostermeier Dagmar University of Basel - BS 01.07.2009 30.06.2012 Project funding

Three-dimensional structure determination of maltoporin and porin by X-ray crystallography
Jansonius Johan Nomdo University of Basel - BS 01.10.1990 30.09.1993 Project funding

Struktur und Funktion lipidhaltiger Bakteriophagen und Tumorviren (Avian Leucosis Viruses)
Franklin Richard University of Basel - BS 01.06.1979 31.05.1982 Project funding

Hyaluronidases: the atomic structures in relation to their func- tioning under normal and pathogenic conditions
Markovic-Housley Zora University of Basel - BS 01.10.2002 31.03.2006 Project funding

Crystallography of membrane proteins that enable solute trans- location
Schirmer Tilman University of Basel - BS 01.04.1999 30.09.2004 Project funding

Cristallographic investigations on three-dimensional structure and catalytic mechanism of vitamin B6-dependent enzymes
Jansonius Johan Nomdo University of Basel - BS 01.04.1993 31.03.1999 Project funding

X-ray crystallographic and microspectrophotometric studies on thecatalytic mechanism of aspartate aminotransferase
Jansonius Johan Nomdo University of Basel - BS 01.04.1989 31.03.1992 Project funding

Biomacromolecular structures, dynamics and interactions by NMR and new developments in NMR technology
Grzesiek Stephan University of Basel - BS 01.10.2005 30.09.2010 Project funding

Computer studies on the mechanism of action of Aspartate Amino- transferase
Mehler Ernest L. University of Basel - BS 01.10.1989 30.09.1993 Project funding

Three-dimensional structure and structure-function relation- ships of enzymes
Jansonius Johan Nomdo University of Basel - BS 01.10.1985 31.03.1989 Project funding

Structure-function studies of recombinant bee venom hyaluronidase
Schirmer Tilman University of Basel - BS 01.10.1997 30.09.2000 Project funding

Biomacromolecular structures, dynamics and interactions by NMR and new developments in NMR technology
Grzesiek Stephan University of Basel - BS 01.04.2017 31.03.2021 Project funding

In vivo and in vitro cellular pathology, immunopathology, and molecular pathology of tumor viruses
Franklin Richard University of Basel - BS 01.06.1982 30.06.1985 Project funding

Diseased muscle reveals cellular components vital to physiological processes
Mayans Olga University of Basel - BS 01.07.2003 30.06.2006 Project funding

Structure and function of integral membrane and dynamic enzymes using high resolution NMR
Pervushin Konstantin University of Basel - BS 01.10.2007 30.09.2010 Project funding

Biomacromolecular structures, dynamics and interactions by NMR and new developments in NMR technology
Grzesiek Stephan University of Basel - BS 01.10.2013 31.03.2017 Project funding

Principles of the oligonucleotide/oligosaccharide binding (OB) fold
Alexandrescu Andrei University of Basel - BS 01.10.1995 30.09.2000 Project funding

Structure and function of prokaryotic membrane permeases and pores and of a two-component response regulator
Schirmer Tilman University of Basel - BS 01.10.2004 31.03.2011 Project funding

Inference of combined quantitative effects of miRNAs and transcription factors on gene expression
Zavolan Mihaela University of Basel - BS 01.04.2013 30.04.2016 Project funding

Structure-activity relationship and inhibitor design of vitamin B6-dependent enzymes
Burkhard Peter University of Basel - BS 01.10.2001 31.03.2005 Project funding

Biochemistry and molecular biology of the human malaria parasite Plasmodium falciparum
Franklin Richard University of Basel - BS 01.07.1991 30.06.1994 Project funding

Three-dimensional structure and structure-function relationships of enzymes
Jansonius Johan Nomdo University of Basel - BS 01.10.1982 30.09.1985 Project funding

Three-dimensional structure and structure-function relation- ships of enzymes and regulatory proteins
Jansonius Johan Nomdo University of Basel - BS 01.04.1989 31.03.1993 Project funding

Molecular mechanisms of c-di-GMP signaling and of target AMPylation
Schirmer Tilman University of Basel - BS 01.02.2012 31.01.2016 Project funding

Conformational dynamics of ATP-driven molecular machines: single molecular FRET studies of helicases and topoisomerases
Klostermeier Dagmar University of Basel - BS 01.04.2006 30.06.2009 Project funding

Biophysical Principles of Chaperone-Client Interactions
Hiller Sebastian University of Basel - BS 01.08.2019 31.07.2022 Project funding

Regulation of mRNA translation and its relationship with disease processes
Zavolan Mihaela University of Basel - BS 01.10.2016 31.12.2019 Project funding

The molecular mechanism of outer membrane protein insertion by BamA and its role as a target for novel antibiotics
Hiller Sebastian University of Basel - BS 01.01.2017 30.06.2021 NRP 72 Antimicrobial Resistance

Die Virusfunktion in der Pathogenese der postinfektiösen Encephalitis und der Multiplen Sklerose.
Schäfer Rolf University of Basel - BS 01.04.1979 31.03.1981 Project funding

Structures, dynamics and interactions of disease-relevant proteins and new developments in NMR technology
Grzesiek Stephan University of Basel - BS 01.04.2021 31.03.2024 Project funding

Biomacromolecular structures, dynamics and interactions by NMR and new developments in NMR technology
Grzesiek Stephan University of Basel - BS 01.10.2010 30.09.2013 Project funding

Struktur und Funktion lipid-haltiger Viren
Franklin Richard University of Basel - BS 01.06.1976 31.05.1979 Project funding
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