Institute

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Name

Département de biochimie médicale Faculté de médecine Université de Genève

Address Département de biochimie médicale Faculté de médecine Université de Genève
Rue Michel-Servet 1
1211
CH-Genève 4
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Projects

Responsible applicant Institution of higher education Start End date Funding scheme

Studies of the ubiquitination of protein substrates and sub- sequent degradation by the ubiquitin system
Jaton Jean-Claude University of Geneva - GE 01.10.1992 30.09.1995 Project funding

Genetic and biochemical analysis of transcriptional regulation inyeast
Collart Martine University of Geneva - GE 01.04.1997 31.03.2000 Project funding

Long term effests of fatty acids and of UCP2 overexpression on pancreatic beta cells: Studies on insulin secretion, mitochon- drial energy metabolism and reactive oxygen species generation
Assimacopoulos-Jeannet Françoise University of Geneva - GE 01.04.2001 31.03.2004 Project funding

Function and regulation of the universally conserved heat shock response
Georgopoulos Costa Panos University of Geneva - GE 01.10.1991 30.09.1996 Project funding

RNA helicases involved in translation initiation and ribosome biogenesis in yeast
Linder Patrick University of Geneva - GE 01.10.2001 30.09.2004 Project funding

Genetic and biochemical analysis of transcriptional regulation in yeast
Collart Martine University of Geneva - GE 01.04.2003 31.03.2008 Project funding

Genetic and biochemical analysis of transcriptional regulation inyeast
Collart Martine University of Geneva - GE 01.04.2000 31.03.2003 Project funding

Enterotoxin gene probes for detection of enterotoxic bacterial enteric pathogens by DNA: DNA hybridization
Timmis Kenneth University of Geneva - GE 01.10.1984 30.09.1987 NRP 17 Alternative Methods to Experiments on Animals

PROSITE and SWISS-PROT: identification of protein function from primary sequence through the development of computational methodsand associated databases
Bairoch Amos University of Geneva - GE 01.04.1993 30.09.1996 Swiss Priority Programmes (SPPs)

Characterization of a de-ubiquitinating enzyme belonging to a novel class of cysteinyl proteases: the 100 kDa de-ubiquitinase from human erythrocytes
Jaton Jean-Claude University of Geneva - GE 01.10.1995 30.06.1999 Project funding

Pathogenesis Mechanisms of Invasive Bacteria
Timmis Kenneth University of Geneva - GE 01.10.1981 30.09.1983 Project funding

Identification of rules governing some post-translational modifications; Classification and phylogeny of ribosomal proteins. ( MHV-Beitrag )
Veuthey Anne-Lise University of Geneva - GE 01.10.1995 31.12.1998 Marie Heim-Voegtlin grants

Molecular mechanisms of the survival of Salmonella typhimurium in murine macrophages
Pechère Jean-Claude University of Geneva - GE 01.10.1993 30.09.1995 Project funding

Function and regulation of the universally conserved heat shock response
Georgopoulos Costa Panos University of Geneva - GE 01.10.2001 30.09.2006 Project funding

Genetic and biochemical analysis of the regulation of gene expression by the Ccr4-Not and NC2 complexes in yeast
Collart Martine University of Geneva - GE 01.04.2008 31.03.2011 Project funding

The genetic determinism of rabbit Immunoglobulin lambda chains in a variant strain lackung kappa light chains
Jaton Jean-Claude University of Geneva - GE 01.10.1977 30.09.1980 Project funding

Studies on inhibition of HIV-1 infection by novel chemokine antagonists
Offord Robin Ewart University of Geneva - GE 01.10.1997 30.09.2000 Project funding (special)

Function and regulation of the universally conserved heat shock response
Georgopoulos Costa Panos University of Geneva - GE 01.10.1996 30.09.2001 Project funding

Biochemical characterization and genetic engineering of bacterialcatabolic enzymes
Kok Menno University of Geneva - GE 01.10.1992 31.12.1993 Project funding

Calalysis of protein folding in Escherichia coli's periplasmatic space
Raina Satish University of Geneva - GE 01.04.1995 31.03.2000 Project funding

Genetic manipulation of pseudomonads and its applications in biotechnology and medicine (workshop)
Timmis Kenneth University of Geneva - GE 01.04.1986 30.09.1986 Scientific Conferences

Molecular analysis and genetic manipulation of bacterial aromatic ring dioxygenases and their use to engineer novel pathways
Harayama Shigeaki University of Geneva - GE 01.10.1987 30.09.1989 Project funding

Causes of increased lipolysis and consequences of high fatty acids on insulin secretion: studies on mitochondrial energy meta-bolism, insulin signalling and gene expression
Assimacopoulos-Jeannet Françoise University of Geneva - GE 01.04.2000 31.03.2001 Project funding

Specific functions of the Beta3-adrenoceptor
Giacobino Jean-Paul University of Geneva - GE 01.10.1998 30.09.2001 Project funding

Translation initiation in the yeast Saccharomyces cerevisiae
Linder Patrick University of Geneva - GE 01.10.1995 30.09.1998 Project funding

Préparation et analyse de protéines et leurs dérivées à des fins cliniques et fondamentales.
Offord Robin Ewart University of Geneva - GE 01.10.1983 30.09.1986 Project funding

Préparation de dérivés de protéines à des fins cliniques et fondamentales
Offord Robin Ewart University of Geneva - GE 01.10.1980 30.09.1983 Project funding

Pathogenesis mechanisms of invasive bacteria
Timmis Kenneth University of Geneva - GE 01.10.1983 31.03.1986 Project funding

Functional analysis of zinc binding sites in 8 deubiquitinases ofthe UBP class; identification and cellular role of an isopepti- dase specific for the ubiquitinated histone H2A
Gabriel Jean-Marc University of Geneva - GE 01.10.2000 31.12.2003 Project funding

Molecular characterization of virulence factors in Salmonellosis
Harayama Shigeaki University of Geneva - GE 01.04.1991 30.04.1992 Project funding

Structural characterization of native and engineered secretory immunoglobulin A
Hughes Graham J. University of Geneva - GE 01.01.1994 30.09.1997 Swiss Priority Programmes (SPPs)

Brown adipose tissue beta-adrenergic receptor and obesity; smooth muscle cell and macrophage derived foam cells and atherosclerosis
Giacobino Jean-Paul University of Geneva - GE 01.01.1990 30.09.1992 Project funding

Préparation et analyse de protéines et leurs dérivés à des fins cliniques et fondamentales
Offord Robin Ewart University of Geneva - GE 01.10.1986 30.09.1989 Project funding

Protein engineering by chemical and enzymatic means: analyses of processing of polypeptide hormones and modification of tumour- specific antibodies for diagnosis and therapy
Offord Robin Ewart University of Geneva - GE 01.10.1989 30.09.1994 Project funding

Studies on inhibition of HIV-1 infection by novel chemokine antagonists
Offord Robin Ewart University of Geneva - GE 01.10.2000 30.09.2005 Project funding (special)

Core activities of the SWISS-PROT protein sequence database
Bairoch Amos University of Geneva - GE 01.01.1997 31.12.1999 Project funding

"Atypical beta-adrenergic receptor and obesity.
Giacobino Jean-Paul University of Geneva - GE 01.10.1992 30.09.1995 Project funding

New functions of the beta2-adrenoceptor
Giacobino Jean-Paul University of Geneva - GE 01.10.2001 30.09.2003 Project funding

Calalysis of protein folding in Escherichia coli's periplasmatic space
Raina Satish University of Geneva - GE 01.04.2000 31.03.2004 Project funding

Translation initiation in the yeast Saccharomyces cerevisiae
Linder Patrick University of Geneva - GE 01.10.1992 30.09.1995 Project funding

Nutrient-regulated protein kineases and cell proliferation control in yeast
De Virgilio Claudio University of Geneva - GE 01.08.2005 31.07.2007 SNSF Professorships

The overall design in the organization of living systems: structure, function, regulation and evolution of bacterial enzy- mes for catabolism of aromatic compounds
Harayama Shigeaki University of Geneva - GE 01.10.1989 30.09.1992 Project funding

Recherches sur le métabolisme des acides gras et le mécanisme de leur synthèse
Favarger Pierre University of Geneva - GE 01.04.1976 31.03.1979 Project funding

Studies of mouse and rabbit immunoglobulin V and C genes and of domain-domain interactions between rabbit secretory components and IgA dimers
Jaton Jean-Claude University of Geneva - GE 01.10.1986 30.09.1989 Project funding

Protein engineering by chemical and enzymatic means
Rose Keith University of Geneva - GE 01.10.1997 30.09.2000 Project funding

Studies of the rabbit immunoglobulin (Ig) locus and of domain- domain interactions between secretory component and polymeric Ig.
Jaton Jean-Claude University of Geneva - GE 01.10.1989 30.09.1992 Project funding

Biological role of the uncoupling protein 3
Muzzin Patrick University of Geneva - GE 01.10.1998 31.03.2002 Project funding

Brown adipose tissue beta-adrenergic receptor and obesity; smooth muscle cell and macrophage derived foam cells and arteriosclerosis
Giacobino Jean-Paul University of Geneva - GE 01.01.1988 31.12.1989 Project funding

Interactions between GroES and GroEL heat shock proteins and their interactions with their substrates (MHV)
Schmeissner-Papazian Ursula University of Geneva - GE 01.01.1992 31.12.1994 Marie Heim-Voegtlin grants

Beta3-adrenoceptor biology
Giacobino Jean-Paul University of Geneva - GE 01.10.1995 30.09.1998 Project funding

Protein engineering by chemical and enzymatic means
Rose Keith University of Geneva - GE 01.10.2000 30.09.2003 Project funding

Pathogenesis Mechanisms of Invasive Bacteria
Timmis Kenneth University of Geneva - GE 01.04.1986 30.09.1989 Project funding

Mechanisms of fatty acid and steroid-induced insulin-resistance: effects on metabolism, insulin signaling and gene expression.
Assimacopoulos-Jeannet Françoise University of Geneva - GE 01.04.1996 30.11.1999 Project funding

Analyse structurale des peptides et des protéines par chromatographie en phase gazeuse - spectrométrie de masse
Offord Robin Ewart University of Geneva - GE 01.10.1980 30.09.1981 Project funding

Structural and serological studies of the immunoglobulin chains of rabbits and mice
Jaton Jean-Claude University of Geneva - GE 01.10.1980 30.09.1983 Project funding

Structural studies of immunoglobulin light chains and of the secretory component of IgA dimers in rabbits
Jaton Jean-Claude University of Geneva - GE 01.10.1983 30.09.1986 Project funding

Protein engineering by chemical and enzymatic means
Rose Keith University of Geneva - GE 01.10.1994 30.09.1997 Project funding

Genetic analysis of transcriptional regulation in yeast
Collart Martine University of Geneva - GE 01.04.1994 31.03.1997 Project funding

The Anâtaxis project: reconstructing the Tree of Life with a new computerised parallel approach
Bairoch Amos University of Geneva - GE 01.04.1999 31.03.2004 Project funding

RNA helicases involved in translation initiation and ribosome biogenesis in yeast
Linder Patrick University of Geneva - GE 01.10.1998 30.09.2001 Project funding
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