Institute

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Name

Biochemisches Institut Universität Zürich

Address Biochemisches Institut Universität Zürich
Winterthurerstrasse 190
8057
CH-Zürich
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Projects

Responsible applicant Institution of higher education Start End date Funding scheme

Signal evolution: A primary sequence investigation of the precursor extensions of preproalbumins
Wilson Kenneth J. University of Zurich - ZH 01.04.1980 31.03.1982 Project funding (Div. I-III)

Katalytische Mechanismen und zellbiologische Aspekte von Enzymen
Christen Philipp University of Zurich - ZH 01.04.1982 31.03.1984 Project funding (Div. I-III)

VIIIth european symposium of the protein society
Plückthun Andreas University of Zurich - ZH 01.06.2009 30.11.2009 Scientific Conferences

The role of arginine methylation of Ewing sarcoma (EWS) protein
Gehring Heinz University of Zurich - ZH 01.10.2002 31.03.2007 Project funding (Div. I-III)

Polyelectrolyte Interactions of Disordered Proteins: Probing a new Paradigm of Biomolecular Recognition
Schuler Benjamin University of Zurich - ZH 01.03.2021 28.02.2025 Project funding (Div. I-III)

Molekulare Studien axonaler Funktionen während Axonwachstum und Synapsenbildung
Sonderegger Peter University of Zurich - ZH 01.10.1985 30.09.1989 Project funding (Div. I-III)

NCCR Structural Biology: Molecular Life sciences: Three Dimensional Structure, Folding and Interactions (phase II)
Grütter Markus Gerhard University of Zurich - ZH 01.05.2005 30.04.2009 National Centres of Competence in Research (NCCRs)

Probing transition paths: An integrated single-molecule approach
Schuler Benjamin University of Zurich - ZH 01.01.2020 31.12.2022 Project funding (Div. I-III)

Katalytische Mechanismen und zellbiologische Aspekte von Enzymen
Christen Philipp University of Zurich - ZH 01.04.1984 31.03.1987 Project funding (Div. I-III)

The Evolution and Ecology of Mobile DNA
Rankin Daniel University of Zurich - ZH 01.03.2009 31.12.2011 Ambizione

Axonal sezernierte Proteine: mögliche Regulatoren von Axonwachs- tum und Synapsenbildung
Sonderegger Peter University of Zurich - ZH 01.10.1989 30.09.1992 Project funding (Div. I-III)

Protein folding and aggregation investigated by single molecule fluorescence spectroscopy
Schuler Benjamin University of Zurich - ZH 01.04.2005 31.03.2008 Project funding (Div. I-III)

Struktur und Funktion von Proteinen
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1985 30.09.1988 Project funding (Div. I-III)

Reinigung und Charakterisierung eines klein-molekularen Zellwachstumsinhibitors aus Kulturen von Hühnerembryo- fibroblasten
Gehring Heinz University of Zurich - ZH 01.10.1987 30.09.1990 Project funding (Div. I-III)

G protein-coupled receptors: from evolving stable receptors to structure and function
Plückthun Andreas University of Zurich - ZH 01.04.2019 31.03.2023 Project funding (Div. I-III)

Horizontal gene transfer and the evolutionary dynamics of infectious plasmids
Wagner Andreas University of Zurich - ZH 01.10.2009 30.09.2012 Project funding (Div. I-III)

Proteinwechselwirkungen in Elektronentransportketten von Membranen
Bosshard Hans Rudolf University of Zurich - ZH 01.10.1980 30.09.1982 Project funding (Div. I-III)

Enzyme engineering, protein folding, and molecular chaperones
Christen Philipp University of Zurich - ZH 01.04.2001 31.03.2004 Project funding (Div. I-III)

Thermodynamic and kinetic dissection of protein-protein and protein-DNA interactions
Bosshard Hans Rudolf University of Zurich - ZH 01.08.1999 31.07.2003 Project funding (Div. I-III)

Structure-function studies of heterodimeric ABC transporters
Seeger Markus University of Zurich - ZH 01.10.2012 31.05.2013 Ambizione

Roles of metallothionein in oxidative stress
Vasak Milan University of Zurich - ZH 01.04.1986 31.03.1989 Project funding (Div. I-III)

Molecular chaperones
Christen Philipp University of Zurich - ZH 01.10.2003 31.03.2005 Project funding (Div. I-III)

Axonin-1, an axonally secreted cell adhesion molecule with a rolein the control of axon growth and guidance during neurogenesis
Sonderegger Peter University of Zurich - ZH 01.10.1992 30.09.1997 Project funding (Div. I-III)

Struktur und Funktion von Proteinen
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1975 30.09.1977 Project funding (Div. I-III)

Specificity, Kinetics and Thermodynamics of Macromolecular Recognition A: Antigen-Antibody Recognition B: Folding and DNA-Binding of bZIP Factors
Bosshard Hans Rudolf University of Zurich - ZH 01.05.1996 31.07.1999 Project funding (Div. I-III)

Computational Studies of Protein Folding and Aggregation
Caflisch Amedeo University of Zurich - ZH 01.10.2007 30.09.2010 Project funding (Div. I-III)

Struktur und Funktion von Proteinen
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1977 30.09.1979 Project funding (Div. I-III)

Protein-Protein Interactions in Electron Transport Chains of Membranes
Bosshard Hans Rudolf University of Zurich - ZH 01.10.1982 30.09.1985 Project funding (Div. I-III)

Structure-function relationships of brain metalloproteins
Vasak Milan University of Zurich - ZH 01.04.1997 31.03.2000 Project funding (Div. I-III)

Untersuchungen über Vitamin B12-Transport im Blut
Fràter-Schröder Marijke University of Zurich - ZH 01.10.1981 30.09.1984 Project funding (Div. I-III)

Probing the interaction mechanisms of intrinsically disordered proteins with single-molecule spectroscopy
Schuler Benjamin University of Zurich - ZH 01.04.2017 30.09.2020 Project funding (Div. I-III)

Protein libraries: understanding molecular stability and applications to intracellular targets
Plückthun Andreas University of Zurich - ZH 01.10.2006 30.09.2009 Project funding (Div. I-III)

Development of a targeted, adenoviral gene therapy platform for optimized delivery of SARS-CoV-2 interventions to the lung
Plückthun Andreas University of Zurich - ZH 01.08.2020 31.07.2022 NRP 78 Covid-19

Photoswitchable oligonucleotide probes for spatiotemporally controlled epitranscriptomic regulation (Photo-ONP)
Omori Elena University of Zurich - ZH 01.01.2020 31.12.2021 Spark

Molecular mechanisms of CRISPR-associated genome editor nucleases
Jinek Martin University of Zurich - ZH 01.10.2018 30.09.2022 Project funding (Div. I-III)

From molecular mechanisms to cellular organization of human anion transport proteins of the LRRC8 and SLC26 families
Dutzler Raimund University of Zurich - ZH 01.10.2021 30.09.2025 Project funding (Div. I-III)

1.) Axon guidance by interaction of axonin-1, NrCAM, and NgCAM 2.) Regulation of extracellular proteolysis at nerve terminals
Sonderegger Peter University of Zurich - ZH 01.10.1997 30.09.2002 Project funding (Div. I-III)

Structure, Function and Pharmacology of CIC Chloride Channels
Dutzler Raimund University of Zurich - ZH 01.04.2004 31.03.2009 Project funding (Div. I-III)

NCCR Structural Biology: Molecular Life sciences: Three Dimensional Structure, Folding and Interactions (phase III)
Grütter Markus Gerhard University of Zurich - ZH 01.05.2009 30.04.2013 National Centres of Competence in Research (NCCRs)

Studies of the structure-function relationship of metallo- thioneins and on the solution structure of rubredoxin from Desulfovibrio gigas
Vasak Milan University of Zurich - ZH 01.04.1989 31.03.1992 Project funding (Div. I-III)

Protein-protein recognition in antigen-antibody complexes and in electron transfer complexes
Bosshard Hans Rudolf University of Zurich - ZH 01.10.1991 30.09.1994 Project funding (Div. I-III)

Artificial receptors, repressors and inhibitors
Gutte Bernd University of Zurich - ZH 01.04.1990 31.12.1991 Project funding (Div. I-III)

Thermodynamic stability of recombinant antibodies: Rational en- gineering and efficient screening methods
Plückthun Andreas University of Zurich - ZH 01.10.1993 30.09.1996 Project funding (Div. I-III)

Localized Immobilization of Macromolecules with Orientational Control
Bosshard Hans Rudolf University of Zurich - ZH 01.05.1996 30.06.2000 NRP 36 Nano Sciences

The Modular Designer Detectome
Plückthun Andreas University of Zurich - ZH 01.12.2017 31.08.2021 Bridge - Discovery

Struktur und Funktion von Proteinen.
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1979 30.09.1982 Project funding (Div. I-III)

Structure-based design of Armadillo Repeat Proteins as a modular recognition system for the sequence-specific binding of peptides
Plückthun Andreas University of Zurich - ZH 01.08.2012 31.07.2015 Sinergia

Hochauflösende Kryo-Elektronentomographie von Kernporenkomplexen in funktionell aktivem und im Ruhezustand
Frangakis Achilleas University of Zurich - ZH 01.02.2016 30.04.2016 International short research visits

Antigenic determinants of proteins
Bosshard Hans Rudolf University of Zurich - ZH 01.10.1985 30.09.1988 Project funding (Div. I-III)

Protein folding and disorder investigated by single molecule fluorescence spectroscopy
Schuler Benjamin University of Zurich - ZH 01.04.2011 31.03.2014 Project funding (Div. I-III)

Antibody engineering: Improving folding and stability by rationalengineering and evolutionary techniques
Plückthun Andreas University of Zurich - ZH 01.10.1996 30.09.2001 Project funding (Div. I-III)

Design of novel biologically active polypeptides
Gutte Bernd University of Zurich - ZH 01.10.1984 30.09.1986 Project funding (Div. I-III)

Rolle von Neurotrypsin im Gehirn. (MHV-Beitrag)
Cesar Marija University of Zurich - ZH 01.01.1999 31.12.2000 Marie Heim-Voegtlin grants

Protein Libraries for intracellular applications
Plückthun Andreas University of Zurich - ZH 01.10.2009 30.09.2012 Project funding (Div. I-III)

Thermodynamics and kinetics of Macromolecular Recognition and Protein Folding
Jelezarov Ilian University of Zurich - ZH 01.06.2003 31.05.2007 Project funding (Div. I-III)

Structure-function relationships of brain metalloproteins
Vasak Milan University of Zurich - ZH 01.04.2003 31.03.2006 Project funding (Div. I-III)

Internationales Symposium: "2nd International Meeting on Metallothionein and Other Low Molecular Weight Metal-binding Proteins"
Kägi Jeremias H.R. University of Zurich - ZH 01.04.1985 30.09.1985 Scientific Conferences

Antibody specificity and conformational adaptation in the anti- gen-antibody complex
Bosshard Hans Rudolf University of Zurich - ZH 01.05.1993 30.04.1996 Project funding (Div. I-III)

Proteins in apoptotic and inflammatory signaling pathways: Structure, function and regulation
Grütter Markus Gerhard University of Zurich - ZH 01.10.2003 30.09.2008 Project funding (Div. I-III)

CHiral2: Untersuchungen zum Ursprung der chiroptischen Eigenschaften von mehrkernigen Metallthiolat-Komplexen (Cluster) in Metallothionein
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1994 30.09.1995 Project funding (special)

Design of novel biologically active polypeptides
Gutte Bernd University of Zurich - ZH 01.10.1986 31.03.1990 Project funding (Div. I-III)

UV-Fluorescence microscopy based incubation and imaging platform for protein and nucleic acid crystals
Dutzler Raimund University of Zurich - ZH 01.12.2013 31.01.2015 R'EQUIP

Disulfide-free anti-Tat and anti-Rev antibodies for efficient expression in the cytoplasm of HIV-infected cells
Plückthun Andreas University of Zurich - ZH 01.10.1996 30.09.1999 Project funding (special)

Struktur und Funktion von Proteinen
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1982 30.09.1985 Project funding (Div. I-III)

Struktur und Funktion von Enzymen
Christen Philipp University of Zurich - ZH 01.04.1976 31.03.1978 Project funding (Div. I-III)

Membrane Function and the Topography of Membrane Components
Bosshard Hans Rudolf University of Zurich - ZH 01.10.1978 30.09.1980 Project funding (Div. I-III)

Struktur und Funktion von Aldolasen
Brenner-Holzach Olga University of Zurich - ZH 01.04.1981 31.03.1986 Project funding (Div. I-III)

Inhibition of extracellular proteolysis
Baici Antonio University of Zurich - ZH 01.01.2007 30.11.2009 Project funding (Div. I-III)

Resolving the organization, assembly and structure of nuclear lamins
Medalia Ohad University of Zurich - ZH 01.04.2018 31.03.2022 Project funding (Div. I-III)

Metabolic network analysis, design, and optimization through Metropolis sampling of network space.
Wagner Andreas University of Zurich - ZH 01.10.2010 28.02.2014 Project funding (Div. I-III)

Regulatory mechanisms in CLC proteins and pentameric ligand-gated ion channels
Dutzler Raimund University of Zurich - ZH 01.04.2012 30.09.2015 Project funding (Div. I-III)

Synthesis of novel biologically active polypeptides and of fragments of natural proteins
Gutte Bernd University of Zurich - ZH 01.10.1982 30.09.1984 Project funding (Div. I-III)

Evolutionary epidemiology of mobile DNA
Wagner Andreas University of Zurich - ZH 01.06.2007 31.05.2010 Project funding (Div. I-III)

Combining Theory and Experiment for the Investigation of Molecular Transition Paths
Makarov Dmitrii University of Zurich - ZH 01.05.2017 30.06.2017 International short research visits

Regulation of gene expression by growth factors via mRNA turnover
Zumstein Peter University of Zurich - ZH 01.04.1989 31.03.1994 Project funding (Div. I-III)

Studies on the structure-function relationship of metallo- thioneins
Vasak Milan University of Zurich - ZH 01.04.1995 31.03.1997 Project funding (Div. I-III)

Struktur und Funktion von Aldolasen
Brenner-Holzach Olga University of Zurich - ZH 01.04.1978 31.03.1981 Project funding (Div. I-III)

Evolution, catalytic mechanisms and cell biological aspects of vitamin B6-dependent enzymes
Christen Philipp University of Zurich - ZH 01.04.1990 31.03.1993 Project funding (Div. I-III)

The functional architecture of lamins and the nuclear lamina
Medalia Ohad University of Zurich - ZH 01.04.2012 31.03.2015 Project funding (Div. I-III)

Design and synthesis of novel biologically active popypeptides
Gutte Bernd University of Zurich - ZH 01.10.1980 30.09.1982 Project funding (Div. I-III)

Probing interaction mechanisms of intrinsically disordered proteins with single-molecule spectroscopy
Schuler Benjamin University of Zurich - ZH 01.04.2014 31.03.2017 Project funding (Div. I-III)

Computational Studies of Protein Folding and Aggregation
Caflisch Amedeo University of Zurich - ZH 01.10.2004 30.09.2007 Project funding (Div. I-III)

Studies on the structure-function relationship of metallo- thioneins and on the solution structure of rubredoxin from Desulfovibrio gigas
Vasak Milan University of Zurich - ZH 01.04.1992 31.03.1995 Project funding (Div. I-III)

Structure and function of the Na+ (or H+) -translocating complex I (NADH: quinone oxidoreductase) and related primary redox pumps
Fritz-Steuber Julia Marlene University of Zurich - ZH 01.05.2004 30.04.2008 SNSF Professorships

Structure and Function of Metallothionein
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1994 28.02.1999 Project funding (Div. I-III)

Protein folding, misfolding and stability
Caflisch Amedeo University of Zurich - ZH 01.10.2001 30.09.2004 Project funding (Div. I-III)

Structural and functional analysis of Helicobacter pylori cysteine-rich protein
Mittl Peer University of Zurich - ZH 01.04.2001 31.03.2004 Project funding (Div. I-III)

Structure and Function of Metallothionein
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1988 30.09.1991 Project funding (Div. I-III)

CHiral2: Untersuchungen zum Ursprung der chiroptischen Eigenschaften von mehrkernigen Metallthiolat-Komplexen (Cluster) in Metallothionein
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1995 30.09.1996 Project funding (special)

Mechanism of action of the molecular chaperone system DnaK/DnaJ/ GrpE
Christen Philipp University of Zurich - ZH 01.10.1994 31.03.1996 Project funding (Div. I-III)

Structural study of human lamins, from nuclear lamina organization to lamin structure
Medalia Ohad University of Zurich - ZH 01.04.2015 31.03.2018 Project funding (Div. I-III)

Design of artificial repressors of HIV replication
Gutte Bernd University of Zurich - ZH 01.01.1992 30.06.1995 Project funding (special)

Switzerland-Japan symposium on structural biology 2006
Grütter Markus Gerhard University of Zurich - ZH 01.09.2006 30.09.2006 International Exploratory Workshops

Methods for probing rapid nonequilibrium dynamics of biomolecules with advanced single-molecule fluorescence spectroscopy
Schuler Benjamin University of Zurich - ZH 01.01.2014 31.12.2017 Project funding (Div. I-III)

Cloning and sequencing of a high molecular weight immunophilin localized on the outer surface of T cells
Gehring Heinz University of Zurich - ZH 01.10.1997 30.09.2001 NRP 38 Diseases of the Nervous System

Computational studies of ligand binding and allostery
Caflisch Amedeo University of Zurich - ZH 01.10.2013 31.12.2016 Project funding (Div. I-III)

CHiral2: Untersuchungen zum Ursprung der chiroptischen Eigenschaften von mehrkernigen Metallthiolat-Komplexen (Cluster) in Metallothionein
Kägi Jeremias H.R. University of Zurich - ZH 01.04.1993 30.09.1994 Project funding (special)

Posttranslational changes in the covalent structure of the prion protein
Christen Philipp University of Zurich - ZH 01.07.1997 30.09.2000 NRP 38 Diseases of the Nervous System

Thermodynamic and kinetic dissection of coiled coil stability.
Bosshard Hans Rudolf University of Zurich - ZH 01.08.2003 31.12.2005 Project funding (Div. I-III)

Protein-protein interactions in electron transport chains
Bosshard Hans Rudolf University of Zurich - ZH 01.10.1985 30.09.1988 Project funding (Div. I-III)

Structure and function of neuronal growth inhibitory factor (GIF)
Vasak Milan University of Zurich - ZH 01.04.1995 31.03.1997 Project funding (Div. I-III)

INPEC 2004 (International Network of Protein Engineering Centre)
Plückthun Andreas University of Zurich - ZH 01.09.2004 28.02.2005 Scientific Conferences

Protein-Protein Interactions
Bosshard Hans Rudolf University of Zurich - ZH 01.10.1988 30.09.1991 Project funding (Div. I-III)

Mechanism of action of Hsp70 molecular chaperone systems. Molecular evolution and engineering of pyridoxal-5'-phosphate- dependent enzymes.
Christen Philipp University of Zurich - ZH 01.04.1996 31.03.2001 Project funding (Div. I-III)

Probing transition paths: From basic principles to biomolecular interactions
Schuler Benjamin University of Zurich - ZH 01.01.2017 31.12.2019 Project funding (Div. I-III)

Beitrag im Rahmen des MD/PhD-Programmes
Koller Michael University of Zurich - ZH 01.10.1997 30.09.2000 MD-PhD fellowships (funded by SNSF)

Analysis of protein simulations and neural activity data
Caflisch Amedeo University of Zurich - ZH 01.01.2020 31.12.2022 Project funding (Div. I-III)

Protein libraries: Designing binding proteins with advanced functionality for cellular studies
Plückthun Andreas University of Zurich - ZH 01.04.2016 31.03.2019 Project funding (Div. I-III)

The structure and function of SLC26 transporters and volume regulated anion channels
Dutzler Raimund University of Zurich - ZH 01.10.2018 30.09.2021 Project funding (Div. I-III)

G protein-coupled receptors: from evolving stable receptors to structure and function
Plückthun Andreas University of Zurich - ZH 01.06.2014 31.05.2017 Project funding (Div. I-III)

The structure and function of SLC26 transporters and pentameric ligand-gated ion channels
Dutzler Raimund University of Zurich - ZH 01.10.2015 30.09.2018 Project funding (Div. I-III)

Protein folding and aggregation investigated by single molecule fluorescence spectroscopy
Schuler Benjamin University of Zurich - ZH 01.04.2008 31.03.2011 Project funding (Div. I-III)

Evolution and catalytic mechanisms of vitamin B6-dependent en- zymes
Christen Philipp University of Zurich - ZH 01.04.1993 31.03.1996 Project funding (Div. I-III)

Molecular modelling of antibody-ligand recognition: methodolo- gical improvements and applications
Caflisch Amedeo University of Zurich - ZH 01.10.1995 30.09.1998 Project funding (Div. I-III)

Energetics of receptor response to ligand binding and structure-function relationships within the +TIP interaction network
Jelezarov Ilian University of Zurich - ZH 01.06.2007 31.05.2010 Project funding (Div. I-III)

Struktur und Funktion von Enzymen
Christen Philipp University of Zurich - ZH 01.04.1980 31.03.1982 Project funding (Div. I-III)

Phenotypic innovation, robustness, and recombination in genome-scale metabolic networks
Wagner Andreas University of Zurich - ZH 01.03.2014 30.09.2017 Project funding (Div. I-III)

A state-of-the-art detector for cryo-electron microscopy
Dutzler Raimund University of Zurich - ZH 01.06.2019 31.05.2020 R'EQUIP

Structure, function and regulation of proteases and inhibitors involved in apoptosis
Grütter Markus Gerhard University of Zurich - ZH 01.10.1998 30.09.2003 Project funding (Div. I-III)

Membrane Fonction and the Topography of Membrane Components
Bosshard Hans Rudolf University of Zurich - ZH 01.10.1976 30.09.1978 Project funding (Div. I-III)

Raumstruktur einer FDP-Aldolase der Klasse I
Brenner-Holzach Olga University of Zurich - ZH 01.04.1983 31.03.1986 Project funding (Div. I-III)

Catalytic Mechanisms and Cell-Biological Aspects of Enzymes
Christen Philipp University of Zurich - ZH 01.04.1987 31.03.1990 Project funding (Div. I-III)

Struktur der gegenseitigen Erkennungsstellen der neuralen Zell- oberflächenmoleküle Axonin-1, NgCAM und NrCAM
Sonderegger Peter University of Zurich - ZH 01.12.1999 30.11.2001 Project funding (Div. I-III)

Aeromonas Aminopeptidase: Structural-Functional Aspects
Wilson Kenneth J. University of Zurich - ZH 01.04.1977 31.03.1980 Project funding (Div. I-III)

Growth factors for vascular endothelial cells.
Böhlen Peter University of Zurich - ZH 01.01.1985 30.06.1988 Project funding (Div. I-III)

Computer simulations of photosynthetic proteins and chromphores
Nonella Marco University of Zurich - ZH 01.10.1997 31.12.1999 Project funding (Div. I-III)

Mono- and multivalent single-chain-antibody-enzyme fusions as immunotoxins and bifunctional antibody constructs
Plückthun Andreas University of Zurich - ZH 01.09.2005 31.12.2008 SCOPES

Nuclear fragmentation and cell death through misrouted trafficking of cathepsin B
Baici Antonio University of Zurich - ZH 01.10.2003 31.12.2006 Project funding (Div. I-III)

Protein libraries: Designing binding proteins with advanced functionality for cellular studies
Plückthun Andreas University of Zurich - ZH 01.04.2013 31.03.2016 Project funding (Div. I-III)

Electrogenic reactions of respiratory NADH: quinone oxidoreductases
Fritz-Steuber Julia Marlene University of Zurich - ZH 01.05.2008 30.04.2010 SNSF Professorships

Targeting multidrug efflux proteins: Studying transport processes across the membrane using designed ankyrin repeat proteins and antibody fragments
Seeger Markus University of Zurich - ZH 01.10.2009 30.09.2012 Ambizione

Neurotrypsin-dependent cleavage of agrin at the synapse: a Hebbian mechanism of CNS circuitry reorganization?
Sonderegger Peter University of Zurich - ZH 01.10.2008 30.09.2013 Project funding (Div. I-III)

Developing a novel intracellular sensor concept for drug screening and diagnostics
Plückthun Andreas University of Zurich - ZH 01.04.2015 31.03.2018 India

Evolutionary epidemiology of mobile DNA
Wagner Andreas University of Zurich - ZH 01.06.2008 31.12.2010 Project funding (Div. I-III)

Structural investigation of chaperone-substrate complexes
Plückthun Andreas University of Zurich - ZH 01.10.1993 30.09.1996 Project funding (Div. I-III)

Mechanisms of ion transport: ClC channels and transporters and pentameric ligand gated ion channels
Dutzler Raimund University of Zurich - ZH 01.04.2009 31.03.2012 Project funding (Div. I-III)

Structure and Function of Metallothionein
Kägi Jeremias H.R. University of Zurich - ZH 01.10.1991 30.09.1994 Project funding (Div. I-III)

Computational Studies of Protein Folding and Aggregation
Caflisch Amedeo University of Zurich - ZH 01.10.2010 30.09.2013 Project funding (Div. I-III)

Extracellular proteolysis at nerve terminals: role in synaptic structure, function and plasticity
Sonderegger Peter University of Zurich - ZH 01.10.2002 30.09.2008 Project funding (Div. I-III)

Analysis of protein simulations and neural activity data
Caflisch Amedeo University of Zurich - ZH 01.01.2017 31.12.2019 Project funding (Div. I-III)

Molecular mechanisms of RNA-guided DNases from prokaryotic adaptive immune systems
Jinek Martin University of Zurich - ZH 01.03.2014 28.02.2018 Project funding (Div. I-III)

Functional analysis of calsyntenin-1, a novel calcium-binding protein of the postsynaptic membrane
Gloor Sergio M. University of Zurich - ZH 01.10.2001 30.09.2004 Project funding (Div. I-III)

Structure-based design of Armadillo Repeat Proteins as a modular recognition system for the sequence-specific binding of peptides
Plückthun Andreas University of Zurich - ZH 01.04.2009 31.07.2012 Sinergia

Ligand design and docking: methodological developments and appli-cations
Caflisch Amedeo University of Zurich - ZH 01.10.1998 30.09.2001 Project funding (Div. I-III)

NCCR Structural Biology: Molecular Life sciences: Three Dimensional Structure, Folding and Interactions (phase I)
Grütter Markus Gerhard University of Zurich - ZH 01.05.2001 30.04.2005 National Centres of Competence in Research (NCCRs)

Paracrine delivery of therapeutic biologicals: developing a new technology for personalized cancer immunotherapy
Plückthun Andreas University of Zurich - ZH 01.01.2017 30.06.2021 Sinergia

Antibody engineering: Improving folding and stability by rationalengineering and evolutionary techniques
Plückthun Andreas University of Zurich - ZH 01.10.2001 30.09.2006 Project funding (Div. I-III)

Role of metallothioneins in Alzheimer's disease and cancer chemotherapy
Vasak Milan University of Zurich - ZH 01.04.2006 31.03.2009 Project funding (Div. I-III)

Struktur und Funktion von Enzymen
Christen Philipp University of Zurich - ZH 01.04.1978 31.03.1980 Project funding (Div. I-III)

Structure-function relationships of brain metalloproteins
Vasak Milan University of Zurich - ZH 01.04.2000 31.03.2003 Project funding (Div. I-III)

Next generation of protein binders and degraders by combining computational design and evolution
Plückthun Andreas University of Zurich - ZH 01.04.2020 31.03.2023 Project funding (Div. I-III)

Molekulare Studien von Mechanismus und Spezifität der Synapsenbildung
Sonderegger Peter University of Zurich - ZH 01.10.1983 30.09.1985 Project funding (Div. I-III)

Structure, function and regulation of proteins involved in apoptotic and inflammatory signalling pathways
Grütter Markus Gerhard University of Zurich - ZH 01.10.2008 30.09.2011 Project funding (Div. I-III)

Structure, function and regulation of proteins involved in apoptotic, inflammatory and innate immunity pathways
Grütter Markus Gerhard University of Zurich - ZH 01.10.2011 28.02.2013 Project funding (Div. I-III)

Structure-based design of inhibitors for HIV-1 aspartic protein- ase, integrase, and reverse transcriptase
Caflisch Amedeo University of Zurich - ZH 01.10.1995 30.09.1998 Project funding (special)

Struktur der gegenseitigen Erkennungsstellen der neuralen Zell- oberflächenmoleküle Axonin-1, NgCAM und NrCAM
Sonderegger Peter University of Zurich - ZH 01.05.1997 30.04.1999 Project funding (Div. I-III)

Role of Disordered Regions in RNA-Binding Proteins for Function and Pathology
Schuler Benjamin University of Zurich - ZH 01.01.2017 31.03.2021 Sinergia
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