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Toward prevention of health effects from acute and chronic noise exposure

English title Toward prevention of health effects from acute and chronic noise exposure
Applicant Röösli Martin
Number 201272
Funding scheme Project funding (special)
Research institution Department of Epidemiology and Public Health Swiss Tropical and Public Health Institute Universität Basel
Institution of higher education University of Basel - BS
Main discipline Methods of Epidemiology and Preventive Medicine
Start/End 01.08.2021 - 31.07.2025
Approved amount 789'130.00
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All Disciplines (2)

Discipline
Methods of Epidemiology and Preventive Medicine
Other disciplines of Engineering Sciences

Keywords (7)

transportation noise; environmental epidemiology; noise barriers; sound insulation window; cardiovascular disease; mental health; SAPALDIA

Lay Summary (German)

Lead
Die epidemiologische Forschung hat in den letzten Jahren Zusammenhänge zwischen verschiedenen kardiometabolischen Erkrankungen und Strassen-, Eisenbahn- und Fluglärm aufgezeigt. Allerdings ist noch wenig über die Auswirkungen auf die psychische Gesundheit und die effektivsten Interventionen zur Reduzierung der lärmbedingten gesundheitlichen Auswirkungen bekannt. In dieser Studie werden mehrere wichtige Forschungsfragen in Bezug auf kurz- und langfristige gesundheitliche Auswirkungen von Verkehrslärm untersucht.
Lay summary

Inhalt und Ziel des Forschungsprojekts

Um die akuten Auswirkungen von Fluglärm auf die psychische Gesundheit von Patienten in einer psychiatrischen Klinik zu untersuchen, wird mittels einer Zeitreihenanalyse die täglich gemessene und modellierte Fluglärmbelastung von einem nahen Flugplatz mit Aggressionsereignissen, täglichem Medikamentenkonsum und der psychischen Gesundheit der Patienten verglichen. In einer anderen Stichprobe von 650 Personen im Alter von 20 bis >80 Jahren wird untersucht, ob und inwiefern körperliche Aktivität und Schlaf den Einfluss von Strassenlärm auf früh erkennbare Marker für kardiometabolische Erkrankungen beeinflussen. In den letzten 20 Jahren haben in der Schweiz schätzungsweise 350’000 bzw. 400’000 Personen von Lärmschutzwänden und Schallschutzfenstern profitiert. Welche Wirkung diese Massnahmen auf die kardiovaskuläre Sterblichkeit haben, wird mittels eines natürlichen experimentellen Ansatzes retrospektiv in der Schweizerischen Nationalen Kohorte erforscht. Dazu werden spektrale Ausbreitungsalgorithmen in aktuelle Lärmmodelle implementiert. In der Analyse werden auch Veränderungen der Lärmbelastung durch lärmarme Beläge, grosse Infrastrukturen und Umzüge berücksichtigt.

Wissenschaftlicher und gesellschaftlicher Kontext des Forschungsprojekts

Die Studie wird unser Verständnis für effektive Präventionsmassnahmen auf individueller und Bevölkerungsebene verbessern. Umfassende Analysen physiologischen Wirkungen auf das Herz-/Kreislaufsystem und den Stoffwechsel werden für die individuelle Prävention beleuchten, ob und inwieweit Lärmwirkungen frühzeitig vermeidbar sind. In Bezug auf die Verhältnisprävention wird nun zum ersten Mal empirisch untersucht, wie sich Lärmschutzmassnahmen auf die kardiovaskuläre Sterblichkeit auswirken. Zudem liefert das Projekt Erkenntnisse zur Lärmwirkung in einer möglicherweise besonders empfindlichen Bevölkerungsgruppe von psychiatrischen Patienten.

Direct link to Lay Summary Last update: 11.05.2021

Responsible applicant and co-applicants

Project partner

Associated projects

Number Title Start Funding scheme
173330 Novel methods for investigating acute and long term effects of transportation noise on health 01.08.2017 Project funding (special)
182815 Functional Aging in Health and Disease - the COmPLETE Project 01.12.2018 Project funding (Div. I-III)
147635 Transportation noise, annoyance, sleep and cardiometabolic risk: an integrated approach on short- and long-term effects 01.01.2014 Sinergia
182871 Impact of air pollution on profibrotic and autophagy related mechanisms involved in the development of the respiratory system in infants 01.10.2018 Project funding (Div. I-III)
173043 Investigating the interplay of job exposures, ambient air pollution and living environment as drivers of the chronic lung disease epidemic The Large-scale LuftiBus-SNC Cohort 01.01.2018 Project funding (special)

Abstract

Background and rationale: Epidemiological research in the last decade has revealed associations between various cardiometabolic diseases and road, railway and aircraft noise. However, still little is known about mental health effects and most effective interventions to reduce health burden from transportation noise exposure. Overall objective: In this study, we will address several important research questions in relation to acute and long-term health effects from transportation noise to enhance our understanding of effective individual and population-level prevention measures. Specific aims: 1.To investigate acute effects of military aircraft noise on mental health in patients at a psychiatric clinic located near a military airport.2.To elucidate the interplay of long-term road traffic noise exposure and physical activity for various cardiometabolic biomarkers in a sample of healthy adults.3.To calculate burden of disease from transportation noise exposure based on most recent evidence from Switzerland and the international epidemiological literature.4.To evaluate preventive effects of noise barriers and soundproof windows on cardiovascular mortality.Methods: Acute noise exposure in a psychiatric clinic located about 5 km from a military airfield (aim 1) will be prospectively measured from 2021 onwards and retrospectively modelled for 2015-2020 based on daily number of flights, aircraft type, air route, and noise footprint. Using a time series approach, acute noise exposure will be linked to acts of aggression events collected systematically during the daily clinic routine since 2015 as well as daily hypnotic drug consumption and systematically collected mental health symptoms data of the patients.In a sample of 650 individuals in the age range of 20 to >80 years, mediation analysis will be conducted to obtain a better understanding of the preventive role of physical activity and sleep for the association of modelled road traffic noise exposure at home and early markers of cardiometabolic disease (aim 2). This rich dataset will allow for a high number of relevant covariables to be included in the analysis. Burden of disease from noise (aim 3) will be directly estimated from the nationwide Swiss National Cohort for cardiovascular diseases and by means of standard health impact assessment methods for all other relevant outcomes of interest. A natural experiment approach will be retrospectively applied to the data from the Swiss National Cohort to quantify changes in cardiovascular mortality risk ratios after implementation of noise barriers and sound insulation windows (aim 4). To do so, we will implement spectral propagation algorithms in current noise models for Swiss-wide exposure assessment to account for the highly frequency dependent diffraction around noise barriers. In the analysis, we will also consider changes in noise exposure from low noise pavements, modifications of large infrastructure and moving home. Expected results and broader impact: Extensive analysis of early markers of cardiometabolic disease in connection with physical activity will illuminate whether and to what extent noise effects are preventable at an early stage, which is relevant for individual prevention. In terms of structural prevention, an estimated 350,000 and 400,000 individuals have respectively profited from noise barriers and sound insulation windows in Switzerland the last 20 years. This study will showcase a unique analysis designed to directly evaluate the health effects of these noise prevention measures. Finally, it will also address acute effects on mental health in a vulnerable population of psychiatric patients to inform strategies for effective mitigation and adaptation measures in the daily clinical routine.
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