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Viral eco-evolutionary dynamics of wild and domestic pollinators under global change (VOODOO)

English title Viral eco-evolutionary dynamics of wild and domestic pollinators under global change (VOODOO)
Applicant Neumann Peter
Number 186532
Funding scheme BiodivERsA
Research institution Institut für Sozial- und Präventivmedizin Universität Bern
Institution of higher education University of Berne - BE
Main discipline Ecology
Start/End 01.03.2020 - 28.02.2023
Approved amount 533'681.00
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All Disciplines (3)

Discipline
Ecology
Zoology
Environmental Research

Keywords (9)

evolution; host shift; local adaptation ; pollinators ; invasive species; tripartite network; virus ; global change; bees

Lay Summary (German)

Lead
1. LeadDie Veränderung der Landschaft durch Landnutzung und invasive Arten kann Bestäuber beeinflussen und das Krankheitsrisiko erhöhen, insbesondere für sich anpassende RNA-Viren. Es bestehen aber erhebliche Wissenslücken für das Potenzial globaler Veränderungen, das Risiko für Änderungen der Viren zu erhöhen, welche zu Verlusten von domestizierten und wilden Bestäubern führen könnte. Neueste Beweise deuten darauf hin, dass viele Insekten von viralen Koinfektionen betroffen sind. Wie die verschiedenen globalen Veränderungen das Krankheitsrisiko beeinflussen bleiben unklar, ebenso ob bestimmte Arten oder Lebensräume als Übertragungsknotenpunkte wirken.
Lay summary

2. Inhalt und Ziel des Forschungsprojekts

Wir werden herauszufinden, wie die ökoepidemiologische Dynamik der Wechselwirkungen zwischen Pflanzen, Bienen und Viren von Individuum zu Gemeinschaftsebene durch Änderungen in der Verfügbarkeit und Qualität der Ressourcen beeinflusst wird, die durch Landnutzung, exotische Pflanzen und Verstädterung verursacht werden. Mithilfe Probenahmen und molekularer Analysen werden dreigliedrige Netzwerke (Pflanze-Bestäuber-Virus) in verschiedenen Landschaften quantifiziert und mithilfe von Modellen analysiert. Wir werden dies mit Halb-Freiland- und Laborexperimenten bei bekannten und alternativen Wirten der Viren verbinden.

3. Wissenschaftlicher und gesellschaftlicher Kontext des Forschungsprojekts

Wir werden mit verschiedenen gesellschaftlichen Akteuren zusammenarbeiten, um komplementäres Wissen uber die Entscheidungsfindung für Risikomanagement und dessen Umsetzung zu integrieren, um nachhaltige gesellschaftliche Ergebnisse zu gewährleisten.

Direct link to Lay Summary Last update: 20.12.2019

Lay Summary (English)

Lead
Pollinators face multiple threats from global change, which may magnify disease risk especially from rapidly adapting RNA viruses shifting hosts. However, the role of global change in driving virus host shifts remains a substantial knowledge gap. Recent evidence points to viral coinfections across pollinators; however, their roles in causing disease and driving losses of managed and wild pollinators is poorly understood.
Lay summary

2. We aim to discover how the eco-epidemiological dynamics of plant-pollinator-virus interactions from individual to community levels are modulated by global change pressures (conventional intensive agriculture, alien plant species, and urbanisation). We will quantify tripartite networks in different landscape contexts through ecological sampling, high-resolution molecular analysis (NGS) and models to reveal pollinator disease hubs and dynamics across organisms and habitats. We will couple this with semi-field and laboratory experiments to test viral fitness and adaptation in known and cryptic host species under nutritional stress.

3. Scientific and societal context of the research project

We will engage with diverse societal actors to integrate complementary knowledge on decision-making, risk management and implementation to ensure sustainable societal outcomes.


Direct link to Lay Summary Last update: 20.12.2019

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Abstract

Pollinators underpin ecosystem and human health, but face multiple threats from global change. Anthropogenic modification of landscape floral resources by land-use and alien species may magnify disease risk by producing nutritional stress in pollinators or re-organising their abundance and community interactions. Emerging infectious diseases (e.g. RNA viruses) often arise through high mutation rates and frequent novel pathogen shifts across species barriers. Close phylogenetic relatives of the original host are typically more susceptible, but viral adaptation can enable replication in novel hosts and following spillback altered virulence in the original host due to the genetic changes. However, why pathogens jump between some species, but not others, and the role of global change in driving host shifts remains a substantial knowledge gap. Recent evidence points to potential viral coinfection across a spectrum of flower-visiting insects; however, their roles in causing disease and the potential for emergent pandemic viruses that drive losses of both managed and wild pollinators is poorly understood. VOODOO aims to discover how the eco-epidemiological dynamics of plant-pollinator-virus interactions from individual to community levels are modulated by changes to the availability and quality of nutritional (floral) resources driven by global change pressures (conventional intensive agriculture, alien plant species, and urbanisation). We will quantify tripartite networks in different landscape contexts through ecological sampling, high-resolution molecular analysis (NGS) and network and eco-epidemiological models to reveal pollinator disease hubs and dynamics across organisms and habitats. We will couple this with laboratory selection experiments testing viral fitness and adaptation in known and cryptic host species under nutritional stress treatments calibrated to field-realistic levels. We will engage with diverse societal actors to integrate complementary knowledge on decision-making, risk management and implementation to ensure sustainable societal outcomes.
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