tautomeric signalling; metal-organic complexes; spectroscopy; molecular design; bioactive compounds; supramolecular chemistry
Georgiev Anton, Yordanov Dancho, Ivanova Nikoleta, Deneva Vera, Vassilev Nikolay, Kamounah Fadhil S., Pittelkow Michael, Crochet Aurelien, Fromm Katharina M., Antonov Liudmil (2021), 7-OH quinoline Schiff bases: are they the long awaited tautomeric bistable switches?, in Dyes and Pigments
, 195, 109739-109739.
Yordanov Dancho, Deneva Vera, Georgiev Anton, Crochet Aurelien, Fromm Katharina M., Antonov Liudmil (2020), Indirect solvent assisted tautomerism in 4-substituted phthalimide 2-hydroxy-Schiff bases, in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
, 237, 118416-118416.
Hristova Silvia, Kamounah Fadhil S., Crochet Aurelien, Vassilev Nikolay, Fromm Katharina M., Antonov Liudmil (2020), OH Group Effect in the Stator of β-Diketones Arylhydrazone Rotary Switches, in Chemistry
, 2(2), 374-389.
Solea Atena B., Cornu Ivan, Deneva Vera, Crochet Aurelien, Fromm Katharina M., Antonov Liudmil, Allemann Christophe, Mamula Olimpia (2020), Tautomerism and Self-Association in the Solution of New Pinene-Bipyridine and Pinene-Phenanthroline Derivatives, in Molecules
, 25(2), 298-298.
Tzvetkov Nikolay T., Stammler Hans-Georg, Hristova Silvia, Atanasov Atanas G., Antonov Liudmil (2019), (Pyrrolo-pyridin-5-yl)benzamides: BBB permeable monoamine oxidase B inhibitors with neuroprotective effect on cortical neurons, in European Journal of Medicinal Chemistry
, 162, 793-809.
Kurteva Vanya B., Lubenov Lubomir A., Shivachev Boris L., Nikolova Rositsa P., Fromm Katharina M. (2018), Betti Bases from 4‐(3‐Pyridazo)‐1‐naphthol: Synthesis, Coordination Behaviour and Unusual Substitution Reactions, in ChemistrySelect
, 3(43), 12017-12021.
Konovalov Bata, Živković Marija D., Milovanović Jelena Z., Djordjević Dragana B., Arsenijević Aleksandar N., Vasić Ivana R., Janjić Goran V., Franich Andjela, Manojlović Dragan, Skrivanj Sandra, Milovanović Marija Z., Djuran Miloš I., Rajković Snežana (2018), Synthesis, cytotoxic activity and DNA interaction studies of new dinuclear platinum( ii ) complexes with an aromatic 1,5-naphthyridine bridging ligand: DNA binding mode of polynuclear platinum( ii ) complexes in relation to the complex structure, in Dalton Transactions
, 47(42), 15091-15102.
Hristova S., Deneva V., Pittelkow M., Crochet A., Kamounah F.S., Fromm K.M., Hansen P.E., Antonov L. (2018), A concept for stimulated proton transfer in 1-(phenyldiazenyl)naphthalen-2-ols, in Dyes and Pigments
, 156, 91-99.
Savić Nada D., Vojnovic Sandra, Glišić Biljana Đ., Crochet Aurélien, Pavic Aleksandar, Janjić Goran V., Pekmezović Marina, Opsenica Igor M., Fromm Katharina M., Nikodinovic-Runic Jasmina, Djuran Miloš I. (2018), Mononuclear silver(I) complexes with 1,7-phenanthroline as potent inhibitors of Candida growth, in European Journal of Medicinal Chemistry
, 156, 760-773.
Glišić Biljana Đ., Nikodinovic-Runic Jasmina, Ilic-Tomic Tatjana, Wadepohl Hubert, Veselinović Aleksandar, Opsenica Igor M., Djuran Miloš I. (2018), Synthesis, cytotoxic activity and DNA-binding properties of copper(II) complexes with terpyridine, in Polyhedron
, 139, 313-322.
Nedeltcheva-Antonova Daniela, Stoicheva Petya, Antonov Liudmil (2017), Chemical profiling of Bulgarian rose absolute (Rosa damascena Mill.) using gas chromatography–mass spectrometry and trimethylsilyl derivatives, in Industrial Crops and Products
, 108, 36-43.
Tzvetkov Nikolay T., Stammler Hans-Georg, Antonov Liudmil (2017), Tautomerism of N -(3,4-dichlorophenyl)-1 H -indazole-5-carboxamide – A new selective, highly potent and reversible MAO-B inhibitor, in Journal of Molecular Structure
, 1149, 273-281.
Pavic Aleksandar, Glišić Biljana Đ., Vojnovic Sandra, Warżajtis Beata, Savić Nada D., Antić Marija, Radenković Slavko, Janjić Goran V., Nikodinovic-Runic Jasmina, Rychlewska Urszula, Djuran Miloš I. (2017), Mononuclear gold(III) complexes with phenanthroline ligands as efficient inhibitors of angiogenesis: A comparative study with auranofin and sunitinib, in Journal of Inorganic Biochemistry
, 174, 156-168.
Živković Marija D., Rajković Snežana, Glišić Biljana Đ., Drašković Nenad S., Djuran Miloš I. (2017), Hydrolysis of the amide bond in histidine- and methionine-containing dipeptides promoted by pyrazine and pyridazine palladium(II)-aqua dimers: Comparative study with platinum(II) analogues, in Bioorganic Chemistry
, 72, 190-198.
Tzvetkov Nikolay T., Stammler Hans-Georg, Neumann Beate, Hristova Silvia, Antonov Liudmil, Gastreich Marcus (2017), Crystal structures, binding interactions, and ADME evaluation of brain penetrant N -substituted indazole-5-carboxamides as subnanomolar, selective monoamine oxidase B and dual MAO-A/B inhibitors, in European Journal of Medicinal Chemistry
, 127, 470-492.
Tzvetkov Nikolay T., Antonov Liudmil (2017), Subnanomolar indazole-5-carboxamide inhibitors of monoamine oxidase B (MAO-B) continued: indications of iron binding, experimental evidence for optimised solubility and brain penetration, in Journal of Enzyme Inhibition and Medicinal Chemistry
, 32(1), 960-967.
Manolova Y., Nedeltcheva D., Antonov L. (2017), 4-Carboxyl-2,6-dinitrophenylazohydroxynaphthalenes tautomerism theoretically re-explained, in Dyes and Pigments
, 136, 663-668.
Marciniak H., Hristova S., Deneva V., Kamounah F. S., Hansen P. E., Lochbrunner S., Antonov L. (2017), Dynamics of excited state proton transfer in nitro substituted 10-hydroxybenzo[h]quinolines, in Phys. Chem. Chem. Phys.
, 19(39), 26621-26629.
Manolova Y., Marciniak H., Tschierlei S., Fennel F., Kamounah F.S., Lochbrunner S., Antonov L. (2017), Solvent control of intramolecular proton transfer: is 4-hydroxy-3-(piperidin-1-ylmethyl)-1- naphthaldehyde a proton crane?, in Physical Chemistry Chemical Physics
, 19, 7316-7325.
Tzvetkov Nikolay T., Neumann Beate, Stammler Hans-Georg, Antonov Liudmil (2016), A simple approach to multifunctionalized N1-alkylated 7-amino-6-azaoxindole derivatives using their in situ stabilized tautomer form, in Tetrahedron
, 72, 6455-6466.
Nedeltcheva Daniela, Antonov Liudmil (2016), Controlled Tautomerism: Is It Possible?, in Antonov Liudmil (ed.), Wiley-VCH, Weinheim, 273-294.
Hristova S., Dobrikov G., Kamounah F.S., Kawauchi S., Hansen P.E., Deneva V., Nedeltcheva D., Antonov L. (2015), 10-Hydroxybenzo[h]quinoline: switching between single- and double-well proton transfer through structural modifications, in RSC Advances
, 5, 102495-102507.
Supramolecular chemistry offers the design of molecular information-controlled, "programmed," and functional self-organizing systems, and provides an original approach to nanoscience, as well as a powerful alternative/complement to nanofabrication, nanomanipulation and drug delivery. All this makes supramolecular chemistry a truly multidisciplinary research subject with great potential for the future development -and logically brings the need for suitable teaching. This training at the level of young researchers and students cannot possibly encompass all biomedical aspects of the supramolecular idea, but must concentrate on the achievements reached with synthetic ligands interacting with biological systems. Following this concept it is clear that the teaching cannot give illustration of all aspects of non-covalent assemblies in the biomedical field. And there is no need to do that! It is enough to make visible, for the young people, the unlimited possibilities of using intermolecular interactions in living systems and to inspire them. The inspiration is the building stone of the current proposal. In this Institutional Partnership we unite the efforts of the Department of Chemistry and the Adolphe Merkle Institute (AMI) (University of Fribourg), the Faculty of Science (University of Kragujevac) and the Institute of Organic Chemistry (Bulgarian Academy of Sciences) in creating of suitable educational background for teaching in supramolecular chemistry and its biomedical applications in the Balkan area. This geographic area, for long time a synonym of violence and instability, is now in a process of transition, success of which crucially depends on the availability of well-educated, motivated, beyond geographical borders minded young people. With SupraMedChem@Balkans.Net we plan to create a solid background in the modern teaching in supramolecular chemistry and to implement the best Swiss educational and research standards. This will be achieved by a three layers approach:- Teaching activities (basic layer), which aim to develop new curricula for teaching in supramolecular chemistry and to provide conditions for training in the general concepts of supramolecular chemistry by organizing Summer/Winter schools;- Training initiatives (upgrade layer), which are directed to increase the capacity of the staff of the partner institutions to do research and education in biomedical supramolecular chemistry through personnel exchange and organizing workshops;- Strengthening the research and renewal of the infrastructure (sustainable development layer) in order to strengthen the training and research capacity of the participating Balkan institutions.Number of important outcomes is expected in respect of the institutional capacity building, but the most substantial benefits are expected for the young people (high school and university students, PhD students and young researchers). This IP provides a unique opportunity to build up an educational profile and research career. We will provide basic (Summer schools) and advanced (Workshops and exchange scheme) teaching by using the complementary expertise (solid state - solution - gas phase; theory - experimental studies) of the partner groups. Through the exchange schemes the trainees will have the opportunity to work in different scientific and cultural environment, to establish new contacts and friendships and to acquire new skills in the research and management. The proposal unites 3 successful research teams, working actively in experimental supramolecular chemistry, and gives a clear perspective for strengthening their research and teaching by creating condition for expansion in the biomedical direction and for collaborative networking in future.