maternal effects; signal transduction; genomic imprinting; gametophyte; arabidopsis; epigenetics; fertilization
Kartal Önder, Schmid Marc W., Grossniklaus Ueli (2020), Cell type-specific genome scans of DNA methylation divergence indicate an important role for transposable elements, in
Genome Biology, 21(1), 172-172.
Hedhly Afif, Nestorova Anna, Herrmann Anja, Grossniklaus Ueli (2020), Acute heat stress during stamen development affects both the germline and sporophytic lineages in Arabidopsis thaliana (L.) Heynh., in
Environmental and Experimental Botany, 173, 103992-103992.
Vogler Hannes, Santos-Fernandez Gorka, Mecchia Martin A, Grossniklaus Ueli (2019), To preserve or to destroy, that is the question: the role of the cell wall integrity pathway in pollen tube growth, in
Current Opinion in Plant Biology, 52, 131-139.
Schmid Marc W., Heichinger Christian, Coman Schmid Diana, Guthörl Daniela, Gagliardini Valeria, Bruggmann Rémy, Aluri Sirisha, Aquino Catharine, Schmid Bernhard, Turnbull Lindsay A., Grossniklaus Ueli (2018), Contribution of epigenetic variation to adaptation in Arabidopsis, in
Nature Communications, 9(1), 4446-4446.
Schmid Marc W., Giraldo-Fonseca Alejandro, Rövekamp Moritz, Smetanin Dmitry, Bowman John L., Grossniklaus Ueli (2018), Extensive epigenetic reprogramming during the life cycle of Marchantia polymorpha, in
Genome Biology, 19(1), 9-9.
Kirioukhova Olga, Shah Jubin N., Larsen Danaé S., Tayyab Muhammad, Mueller Nora E., Govind Geetha, Baroux Célia, Federer Michael, Gheyselinck Jacqueline, Barrell Philippa J., Ma Hong, Sprunck Stefanie, Huettel Bruno, Wallace Helen, Grossniklaus Ueli, Johnston Amal J. (2018), Aberrant imprinting may underlie evolution of parthenogenesis, in
Scientific Reports, 8(1), 10626-10626.
Kirioukhova Olga, Shah Jubin N., Larsen Danaé S., Tayyab Muhammad, Mueller Nora E., Govind Geetha, Baroux Célia, Federer Michael, Gheyselinck Jacqueline, Barrell Philippa J., Ma Hong, Sprunck Stefanie, Huettel Bruno, Wallace Helen, Grossniklaus Ueli, Johnston Amal J. (2018), Aberrant imprinting may underlie evolution of parthenogenesis, in
Scientific Reports, 8(1), 10626-10626.
Pires Nuno D., Grossniklaus Ueli (2018),
Identification of Parent-of-Origin-Dependent QTLs Using Bulk-Segregant Sequencing (Bulk-Seq), Springer New York, New York, NY.
Franck Christina, Westermann Jens, Bürssner Simon, Lentz Roswitha, Lituiev Dmytro S, Boisson-Dernier Aurélien (2018), The protein phosphatases ATUNIS1 and ATUNIS2 regulated cell wall integrity in tip-growing cells., in
The Plant Cell.
Mecchia Martin A., Santos-Fernandez Gorka, Duss Nadine N., Somoza Sofía C., Boisson-Dernier Aurélien, Gagliardini Valeria, Martínez-Bernardini Andrea, Fabrice Tohnyui Ndinyanka, Ringli Christoph, Muschietti Jorge P., Grossniklaus Ueli (2017), RALF4/19 peptides interact with LRX proteins to control pollen tube growth in Arabidopsis, in
Science, 358(6370), 1600-1603.
Bowman John L., Kohchi Takayuki, Yamato Katsuyuki T., Jenkins Jerry, Shu Shengqiang, Ishizaki Kimitsune, Yamaoka Shohei, Nishihama Ryuichi, Nakamura Yasukazu, Berger Frédéric, Adam Catherine, Aki Shiori Sugamata, Althoff Felix, Araki Takashi, Arteaga-Vazquez Mario A., Balasubrmanian Sureshkumar, Barry Kerrie, Bauer Diane, Boehm Christian R., Briginshaw Liam, Caballero-Perez Juan, Catarino Bruno, Chen Feng, Chiyoda Shota, et al. (2017), Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome, in
Cell, 171(2), 287-304.e15.
Vogler Hannes, Grossniklaus Ueli, Hedhly Afif (2017),
Plant Germline Development, Springer New York, New York, NY.
Zhao Xin’Ai, Bramsiepe Jonathan, Van Durme Matthias, Komaki Shinichiro, Prusicki Maria Ada, Maruyama Daisuke, Forner Joachim, Medzihradszky Anna, Wijnker Erik, Harashima Hirofumi, Lu You, Schmidt Anja, Guthörl Daniela, Logroño Rosa Sahún, Guan Yonsheng, Pochon Gaetan, Grossniklaus Ueli, Laux Thomas, Higashiyama Tetsuya, Lohmann Jan U., Nowack Moritz K., Schnittger Arp (2017), RETINOBLASTOMA RELATED1 mediates germline entry in Arabidopsis, in
Science, 356(6336), eaaf6532-eaaf6532.
Vogler Hannes, Martinez-Bernardini Andrea, Grossniklaus Ueli (2016), Maybe she's NOT the boss: male–female crosstalk during sexual plant reproduction, in
Genome Biology, 17(1), 96-96.
Vogler Hannes, Martinez-Bernardini Andrea, Grossniklaus Ueli (2016), Maybe she's NOT the boss: male–female crosstalk during sexual plant reproduction, in
Genome Biology, 17(1), 96-96.
Hedhly Afif, Vogler Hannes, Schmid Marc W., Pazmino Diana, Gagliardini Valeria, Santelia Diana, Grossniklaus Ueli (2016), Starch Turnover and Metabolism during Flower and Early Embryo Development, in
Plant Physiology, 172(4), 2388-2402.
Rövekamp Moritz, Bowman John L., Grossniklaus Ueli (2016), Marchantia Mp RKD Regulates the Gametophyte-Sporophyte Transition by Keeping Egg Cells Quiescent in the Absence of Fertilization, in
Current Biology, 26(13), 1782-1789.
Rövekamp Moritz, Bowman John L., Grossniklaus Ueli (2016), Marchantia Mp RKD Regulates the Gametophyte-Sporophyte Transition by Keeping Egg Cells Quiescent in the Absence of Fertilization, in
Current Biology, 26(13), 1782-1789.
Sedeek Khalid E.M., Whittle Edward, Guthörl Daniela, Grossniklaus Ueli, Shanklin John, Schlüter Philipp M. (2016), Amino Acid Change in an Orchid Desaturase Enables Mimicry of the Pollinator’s Sex Pheromone, in
Current Biology, 26(11), 1505-1511.
Florez Rueda Ana Marcela, Grossniklaus Ueli, Schmidt Anja (2016), Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types, in
Journal of Visualized Experiments, (111), 53916.
Wuest Samuel Elias, Philipp Matthias Anton, Guthörl Daniela, Schmid Bernhard, Grossniklaus Ueli (2016), Seed Production Affects Maternal Growth and Senescence in Arabidopsis, in
Plant Physiology, 171(1), 392-404.
Müller Lena M., Lindner Heike, Pires Nuno D., Gagliardini Valeria, Grossniklaus Ueli (2016), A subunit of the oligosaccharyltransferase complex is required for interspecific gametophyte recognition in Arabidopsis, in
Nature Communications, 7, 10826-10826.
Pires Nuno D., Bemer Marian, Müller Lena M., Baroux Célia, Spillane Charles, Grossniklaus Ueli (2016), Quantitative Genetics Identifies Cryptic Genetic Variation Involved in the Paternal Regulation of Seed Development, in
PLOS Genetics, 12(1), e1005806-e1005806.
Schmid Marc W., Schmidt Anja, Grossniklaus Ueli (2015), The female gametophyte: an emerging model for cell type-specific systems biology in plant development, in
Frontiers in Plant Science, 6, 907.
Boisson-Dernier Aurélien, Franck Christina Maria, Lituiev Dmytro S., Grossniklaus Ueli (2015), Receptor-like cytoplasmic kinase MARIS functions downstream of Cr RLK1L-dependent signaling during tip growth, in
Proceedings of the National Academy of Sciences, 112(39), 12211-12216.
Lindner Heike, Kessler Sharon A., Müller Lena M., Shimosato-Asano Hiroko, Boisson-Dernier Aurélien, Grossniklaus Ueli (2015), TURAN and EVAN Mediate Pollen Tube Reception in Arabidopsis Synergids through Protein Glycosylation, in
PLOS Biology, 13(4), e1002139-e1002139.
Schmidt A., Schmid M. W., Grossniklaus U. (2015), Plant germline formation: common concepts and developmental flexibility in sexual and asexual reproduction, in
Development, 142(2), 229-241.
Kessler S. A., Lindner H., Jones D. S., Grossniklaus U. (2015), Functional analysis of related CrRLK1L receptor-like kinases in pollen tube reception, in
EMBO reports, 16(1), 107-115.
Baroux Célia, Grossniklaus Ueli (2015), The Maternal-to-Zygotic Transition in Flowering Plants, Elsevier, New York, 351-371.
We are using genetic and molecular approaches to identify genes required for the development and function of the female gametophyte in Arabidopsis thaliana focusing on two intimately related areas: (i) the isolation and characterisation of genes involved in female gametophyte development, and (ii) the elucidation of mechanisms involved in the maternal control of the seed development.To elucidate the mechanisms that control gametophyte development at the molecular and genetic level with an emphasis on cell specification and fertilization. Studies directed towards the elucidation of cell specification and signaling processes during plant sexual reproduction address fundamental aspects of development such as the role of positional information, cell lineage, and cell-cell communication. The female gametophyte with its small number of distinct cell types and specific interactions with neighboring cells and/or the pollen tube is ideally suited to address such questions