Project

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Metabolic and functional signature of senescent CD8+ T cells

Applicant Burgener Anne-Valerie
Number 158119
Funding scheme MD-PhD fellowships (funded by SNSF)
Research institution
Institution of higher education University of Basel - BS
Main discipline Immunology, Immunopathology
Start/End 01.11.2014 - 31.10.2017
Approved amount 180'000.00
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Keywords (4)

immunosenescence; CD8+ T cell metabolism; memory recall response; aerobic glycolysis

Responsible applicant and co-applicants

Publications

Publication
Vedolizumab as a successful treatment of CTLA-4 associated autoimmune enterocolitis.
Alexander A Navarini Petr Hruz Christoph T Berger Rebecca Higgins Charlotte Schwab Natalie Fred (2017), Vedolizumab as a successful treatment of CTLA-4 associated autoimmune enterocolitis., in J Allergy Clin Immunol, 1043.
Myoperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage
Nura Schürmann Pascal Forrer Olivier Casse Jiagui Li Boas Felmy Anne-Valérie Burgener Nikolaus (2017), Myoperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage, in nature microbiology, 16268.
Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function.
Balmer Maria Louisa, Hess Christoph (2016), Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function., in Immunity, 44(6), 1312-1324.
T-cell metabolism governing activation, proliferation and differentiation; a modular view
Sarah Dimeloe, Anne-Valérie Burgener, Jasmin Grählert, Christoph Hess (2016), T-cell metabolism governing activation, proliferation and differentiation; a modular view, in Immunology, 10/1111/im.
Tissue Distribution Dynamics of Human NK Cells Inferred from Peripheral Blood Depletion Kinetics after Sphingosine-1-Phosphate Receptor Blockade
Mehling Matthias, Burgener Anne-Valérie, Brinkmann Volmar, Bantug Glenn, Dimeloe Sarah, Hoenger Gideon, Kappos Ludwig, Hess Christoph (2015), Tissue Distribution Dynamics of Human NK Cells Inferred from Peripheral Blood Depletion Kinetics after Sphingosine-1-Phosphate Receptor Blockade, in Scandinavian Journal of immunology, 82(5), 460-466.

Collaboration

Group / person Country
Types of collaboration
Immunobiology Spain (Europe)
- in-depth/constructive exchanges on approaches, methods or results

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
MD PhD Retreat Talk given at a conference Immunometabolism in primary Immunodeficiency 10.11.2017 Luzern, Switzerland Burgener Anne-Valerie;
European MD PhD Retreat Talk given at a conference Immunometabolism in primary Immunodeficiency 13.10.2017 Basel, Switzerland Burgener Anne-Valerie;
UBICO Retreat Basel Poster Immunometabolism in primary Immunodeficiency 02.11.2015 Engelberg, Switzerland Burgener Anne-Valerie;


Self-organised

Title Date Place
Immuno PhD Club 05.02.2015 Basel, Switzerland

Communication with the public

Communication Title Media Place Year
Talks/events/exhibitions Uninacht Basel German-speaking Switzerland 2015

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