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Dynamic Networks of Perception, Cognition and Action

Applicant Plomp Gijs
Number 157420
Funding scheme SNSF Professorships
Research institution Departement für Psychologie Universität Freiburg
Institution of higher education University of Fribourg - FR
Main discipline Psychology
Start/End 01.04.2015 - 31.03.2019
Approved amount 1'627'512.00
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All Disciplines (2)

Discipline
Psychology
Neurophysiology and Brain Research

Keywords (8)

Granger causality; Functional connectivity; Networks; Electroencephalography (EEG); Electrophysiology; Dynamics; Visual perception; Cognition

Lay Summary (German)

Lead
Die visuelle Wahrnehmung ist eine der wichtigsten Informationsquellen über unsere Umwelt. Visuelle Wahrnehmung informiert uns über den Stand der Umwelt in Bezug auf unsere aktuellen Ziele und Motivationen und dient dazu, dass wir unser Verhalten entsprechend anpassen können. Bislang ist noch wenig darüber bekannt, wie die dynamische Koordination der Aktivität in unterschiedlichen Gehirnarealen dazu führt, dass unsere visuelle Wahrnehmung unser Denken und Handeln informiert.
Lay summary

Inhalt und Ziel des Forschungsprojekts

In diesem Projekt werden in mehreren Experimenten visuelle Stimulation und Ziele des Beobachters unabhängig voneinander variiert, während die Gehirnaktivität beim Menschen nicht-invasiv mit Hilfe der Elektroenzephalographie (EEG) gemessen wird. Die zeitliche Dynamik, die der Interaktion der dabei aktiven Hirnareale zugrunde liegt, wird mit modernen Netzwerk-basierten Analysemethoden untersucht. Dies liefert Aufschluss darüber, wie dieselbe visuelle Informationen in Abhängigkeit unterschiedlicher Ziele variieren kann.

Ein weiterer Teilaspekt des Projektes beschäftigt sich mit den elementaren Mechanismen, die dem Informationsaustausch zwischen Hirnarealen zugrunde liegen. Dazu wird die elektrische Gehirnaktivität direkt im Tiermodell gemessen, was in Kollaboration mit der Abteilung für Physiologie der Universität Fribourg stattfindet.


Wissenschaftlicher und gesellschaftlicher Kontext des Forschungsprojekts

Das Ziel des Projektes ist, besser zu verstehen, wie unterschiedlichen Hirnareale miteinander kommunizieren, und wie solche Interaktionen zwischen Hirnarealen es ermöglichen, visuelle Information mit unseren Zielen und Handlungen zu vereinbaren.
Direct link to Lay Summary Last update: 16.03.2015

Responsible applicant and co-applicants

Employees

Publications

Publication
A regularized and smoothed General Linear Kalman Filter for more accurate estimation of time-varying directed connectivity *
Pagnotta Mattia F., Plomp Gijs, Pascucci David (2019), A regularized and smoothed General Linear Kalman Filter for more accurate estimation of time-varying directed connectivity *, in 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMB, Berlin, Germany2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMB, Berlin, Germany.
Time-varying effective EEG source connectivity: the optimization of model parameters *
Rubega M., Pascucci D., Queralt J. Rue, Van Mierlo P., Hagmann P., Plomp G., Michel C.M (2019), Time-varying effective EEG source connectivity: the optimization of model parameters *, in 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMB, Berlin, Germany2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMB, Berlin, Germany.
Laws of concatenated perception: Vision goes for novelty, decisions for perseverance
Pascucci David, Mancuso Giovanni, Santandrea Elisa, Della Libera Chiara, Plomp Gijs, Chelazzi Leonardo (2019), Laws of concatenated perception: Vision goes for novelty, decisions for perseverance, in PLOS Biology, 17(3), e3000144-e3000144.
Directed functional connections underlying spontaneous brain activity
Coito Ana, Michel Christoph M., Vulliemoz Serge, Plomp Gijs (2019), Directed functional connections underlying spontaneous brain activity, in Human Brain Mapping, 40(3), 879-888.
Layer 3 Dynamically Coordinates Columnar Activity According to Spatial Context
Plomp Gijs, Larderet Ivan, Fiorini Matilde, Busse Laura (2019), Layer 3 Dynamically Coordinates Columnar Activity According to Spatial Context, in The Journal of Neuroscience, 39(2), 281-294.
Estimating EEG Source Dipole Orientation Based on Singular-value Decomposition for Connectivity Analysis
Rubega M., Carboni M., Seeber M., Pascucci D., Tourbier S., Toscano G., Van Mierlo P., Hagmann P., Plomp G., Vulliemoz S., Michel C. M. (2018), Estimating EEG Source Dipole Orientation Based on Singular-value Decomposition for Connectivity Analysis, in Brain Topography, 1.
Assessing the performance of Granger–Geweke causality: Benchmark dataset and simulation framework
Pagnotta Mattia F., Dhamala Mukesh, Plomp Gijs (2018), Assessing the performance of Granger–Geweke causality: Benchmark dataset and simulation framework, in Data in Brief, 21, 833-851.
Directed functional connections underlying spontaneous brain activity
Coito Ana, Michel Christoph M., Vulliemoz Serge, Plomp Gijs (2018), Directed functional connections underlying spontaneous brain activity, in Human Brain Mapping, 40(3), 879-888.
Benchmarking nonparametric Granger causality: Robustness against downsampling and influence of spectral decomposition parameters
Pagnotta Mattia F., Dhamala Mukesh, Plomp Gijs (2018), Benchmarking nonparametric Granger causality: Robustness against downsampling and influence of spectral decomposition parameters, in NeuroImage.
Time-varying MVAR algorithms for directed connectivity analysis: Critical comparison in simulations and benchmark EEG data
Pagnotta Mattia F., Plomp Gijs (2018), Time-varying MVAR algorithms for directed connectivity analysis: Critical comparison in simulations and benchmark EEG data, in PLOS ONE, 13(6), e0198846-e0198846.
Gating by induced Α-Γ asynchrony in selective attention
Pascucci David, Hervais-Adelman Alexis, Plomp Gijs (2018), Gating by induced Α-Γ asynchrony in selective attention, in Human Brain Mapping.
Early alterations of social brain networks in young children with autism
Sperdin Holger Franz, Coito Ana, Kojovic Nada, Rihs Tonia Anahi, Jan Reem Kais, Franchini Martina, Plomp Gijs, Vulliemoz Serge, Eliez Stephan, Michel Christoph Martin, Schaer Marie (2018), Early alterations of social brain networks in young children with autism, in eLife, 7, 1-23.
Automated diagnosis of temporal lobe epilepsy in the absence of interictal spikes
Verhoeven Thibault, Coito Ana, Plomp Gijs, Thomschewski Aljoscha, Pittau Francesca, Trinka Eugen, Wiest Roland, Schaller Karl, Michel Christoph, Seeck Margitta, Dambre Joni, Vulliemoz Serge, van Mierlo Pieter (2018), Automated diagnosis of temporal lobe epilepsy in the absence of interictal spikes, in NeuroImage: Clinical, 17, 10-15.
Systematic population spike delays across cortical layers within and between primary sensory areas
Plomp Gijs, Michel Christoph M., Quairiaux Charles (2017), Systematic population spike delays across cortical layers within and between primary sensory areas, in Scientific Reports, 7(1), 15267-15267.
Comparison of Neuroplastic Responses to Cathodal Transcranial Direct Current Stimulation and Continuous Theta Burst Stimulation in Subacute Stroke
Nicolo Pierre, Magnin Cécile, Pedrazzini Elena, Plomp Gijs, Mottaz Anaïs, Schnider Armin, Guggisberg Adrian G. (2017), Comparison of Neuroplastic Responses to Cathodal Transcranial Direct Current Stimulation and Continuous Theta Burst Stimulation in Subacute Stroke, in Archives of Physical Medicine and Rehabilitation, 1.
Directed Functional Brain Connectivity Based on EEG Source Imaging: Methodology and Application to Temporal Lobe Epilepsy
Coito Ana, Michel Christoph M., van Mierlo Pieter, Vulliemoz Serge, Plomp Gijs (2016), Directed Functional Brain Connectivity Based on EEG Source Imaging: Methodology and Application to Temporal Lobe Epilepsy, in IEEE Transactions on Biomedical Engineering, 63(12), 2619-2628.
Altered directed functional connectivity in temporal lobe epilepsy in the absence of interictal spikes: A high density EEG study
Coito Ana, Genetti Melanie, Pittau Francesca, Iannotti Giannina R., Thomschewski Aljoscha, Höller Yvonne, Trinka Eugen, Wiest Roland, Seeck Margitta, Michel Christoph M., Plomp Gijs, Vulliemoz Serge (2016), Altered directed functional connectivity in temporal lobe epilepsy in the absence of interictal spikes: A high density EEG study, in Epilepsia, 57(3), 402-411.
Early recurrence and ongoing parietal driving during elementary visual processing
Plomp Gijs, Hervais-Adelman Alexis, Astolfi Laura, Michel Christoph M. (2015), Early recurrence and ongoing parietal driving during elementary visual processing, in Scientific Reports, 5, 18733-18733.
Spectrally weighted Granger-causal modeling: Motivation and applications to data from animal models and epileptic patients
Plomp Gijs, Astolfi Laura, Coito Ana, Michel Christoph M. (2015), Spectrally weighted Granger-causal modeling: Motivation and applications to data from animal models and epileptic patients, in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (E, MilanEMBS, Milan.

Collaboration

Group / person Country
Types of collaboration
Prof. Patric Hagmann, CHUV, Lausanne Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
Prof. Gregor Rainer, Visual Cognition Laboratory, University of Fribourg Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Exchange of personnel
Prof. Laura Busse, Division of Neurobiology, Ludwig-Maximilians-Universität Münch Germany (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Exchange of personnel
Prof. Eric Rouiller, lab of Neurophysiology of Action and Hearing, University of Fribourg Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Exchange of personnel
Dr. Charles Quairiaux, Prof. Christoph Michel, Functional Brain Mpaping lab, University of Geneva Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Prof. Laura Astolfi, Dept. of Computer, Control, and Management Engineering, University of Rome Italy (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
SSN 2019 Poster Dynamic interactions between cortical layers of M1 and S1 in fine grasping behavior 01.02.2019 Geneva, Switzerland Mancuso Giovanni; Plomp Gijs;
LNAM 2018 Talk given at a conference Dynamics of directed interactions in visuo-cognitive processing 03.09.2018 Les Diablerets, Switzerland Plomp Gijs;
LNAM 2018 Poster Functional mechanisms of feature-based attentional control as revealed by fMRI and EEG 03.09.2018 Les Diablerets, Switzerland Pagnotta Mattia Federico;
CSAIL 2018 Talk given at a conference Dynamics of directed interactions in visuo-cognitive processing 26.07.2018 Hood River OR, United States of America Plomp Gijs;
OCNS 2018 Talk given at a conference Fast directed interactions between brain areas and cortical layers 13.07.2018 Seattle , United States of America Plomp Gijs;
Vision Science Society meeting 2018 Talk given at a conference Laws of concatenated perception: vision goes for novelty, decisions for perseverance 22.05.2018 Florida, United States of America Pascucci David;
Alpine Brain Imaging Meeting 2018 Poster Dynamic neural mechanisms of feature-based attentional control as revealed by fMRI and EEG 07.01.2018 Champery, Switzerland Pagnotta Mattia Federico; Plomp Gijs; Pascucci David;
Alpine Brain Imaging Meeting 2018 Talk given at a conference A constrained Kalman filter approach to inform dynamic functional connectivity with anatomical priors 07.01.2018 Champery, Switzerland Plomp Gijs; Pascucci David;
Society for Neuroscience Meeting 2017 Poster Laminar functional connectivity in mouse V1 is tuned to stimulus size at early latencies 11.11.2017 Chicago, United States of America Plomp Gijs;
LN Annual Meeting (LNAM) - Lemanic Neuroscience 2017 Poster Investigation of visual selective attention mechanisms in humans 01.09.2017 Les Diablerets, Switzerland Pagnotta Mattia Federico; Plomp Gijs;
3rd International Conference on Basic and Clinical Multimodal Imaging Poster Dynamic Granger-causality: methods comparison in numerical simulations and benchmark EEG data 29.08.2017 bern, Switzerland Pagnotta Mattia Federico; Plomp Gijs;
3rd International Conference on Basic and Clinical Multimodal Imaging Talk given at a conference Gating by induced α-γ asynchrony in selective attention 29.08.2017 Bern, Switzerland Pascucci David; Plomp Gijs;
13th International Conference for Cognitive Neuroscience Poster Gating by induced α-γ asynchrony in selective attention 05.08.2017 Amsterdam, Netherlands Plomp Gijs; Pascucci David;
13th International Conference for Cognitive Neuroscience Poster Dynamic Granger-causality: methods comparison in numerical simulations and benchmark EEG data 05.08.2017 Amsterdam, Netherlands Pagnotta Mattia Federico; Plomp Gijs;
BrainModes 2016 Poster Directed interactions from parietal cortex orchestrate the selective processing of visual stimuli 01.12.2016 Brussels, Belgium Plomp Gijs; Pascucci David;
LN Annual Meeting (LNAM) - Lemanic Neuroscience 2016 Poster Comparison of different estimators for time-varying directed connectivity using benchmark EEG data 02.09.2016 Les Diablerets, Switzerland Pagnotta Mattia Federico;
OHBM 2016 - Organization for Human Brain Mapping Poster Top-down influences on perceptual networks: EEG-based Granger causality and fMRI results 26.06.2016 Geneva, Switzerland Pascucci David;
Alpine Brain Imaging Meeting Poster Bayes Factors for Electrical Neuroimaging: Hello evidence, goodbey p-values? 10.01.2016 Champery, Switzerland Plomp Gijs;
BrainModes Talk given at a conference Local and large-scale interactions between cortical layers in sensory processes 10.12.2015 Atlanta, United States of America Plomp Gijs;
Society for Neuroscience Meeting 2015 Poster Upward propagation of spiking activity across cortical layers 17.10.2015 Chicago, United States of America Plomp Gijs;
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society Talk given at a conference Spectrally weighted Granger-causal modeling: Motivation and applications to data from animal models and epileptic patients 25.08.2015 Milan, Italy Plomp Gijs;


Communication with the public

Communication Title Media Place Year
Talks/events/exhibitions Science slam German-speaking Switzerland 2018

Associated projects

Number Title Start Funding scheme
131731 Functional brain networks: dynamics of directed information transfer in visual processes 01.01.2011 Ambizione
183714 Dynamic Networks of Perception, Cognition and Action 01.04.2019 SNSF Professorships
190065 Dynamic Networks of Perception, Cognition and Action 01.04.2020 SNSF Professorships

Abstract

The primary function of visual perception is to inform cognition and action. But how vision and its interrelated aspects arise from quickly coordinated activity in multiple brain areas is not well understood. This project uses a recently developed dynamic network approach that combines EEG source-imaging, fMRI and Granger-causal modeling to study directed interactions between brain areas in vision with high temporal resolution. Three lines of research are proposed: one for investigating the dynamic interactions underlying visual function in humans, a second for the systematic evaluation of connectivity methods, and a third for identifying the elementary cortical mechanisms underlying visual processing in animal models. The cross-disciplinary approach is expected to link psychological theories to elementary mechanisms and to provide a better understanding of vision and its function for the organism.
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