Project

Back to overview

Biology Needs Ultra High Throughput DNA Sequencing

English title Biology Needs Ultra High Throughput DNA Sequencing
Applicant Cole Stewart
Number 133797
Funding scheme R'EQUIP
Research institution Global Health Institute EPFL SV-DO
Institution of higher education EPF Lausanne - EPFL
Main discipline Molecular Biology
Start/End 01.06.2011 - 31.05.2012
Approved amount 252'265.00
Show all

All Disciplines (2)

Discipline
Molecular Biology
Genetics

Keywords (18)

Evolutionary genomics; Genetics; Chromatin immunoprecipitation; Transcriptomics; Social organisation; Cell cycle; Gene expression; Insulin response; Nutrient cycle; ChIP-Seq; Epigenetics; KAP1; Embryonic stem cells; Human disease; Viral infections; Disease predisposition; Drug discovery; Pluripotentiality

Responsible applicant and co-applicants

Publications

Publication
Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein.
Blasco Benjamin (2012), Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein., in PLoS Pathog , 8(3), 1-12.
Combining RT-PCR-seq and RNA-seq to catalog all genic elements encoded in the human genome
Howald C., Combining RT-PCR-seq and RNA-seq to catalog all genic elements encoded in the human genome, in Genome Research, 22(9), 1698-1710.
Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during circadian cycles
LeMartelot G., Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during circadian cycles, in Plos Biology, 10(11).
The KRAB-ZFP/KAP1 system is responsible for the early embryonic establishment of site-specific DNA methylation patterns maintained during development
Quenneville S, The KRAB-ZFP/KAP1 system is responsible for the early embryonic establishment of site-specific DNA methylation patterns maintained during development, in Cell Reports, 2(4), 766-773.

Associated projects

Number Title Start Funding scheme
125230 Revealing RNA polymerase II and III transcriptional programs in human cells 01.08.2009 Sinergia
140778 Structure-function analysis of the protein secretion system ESX-1 of Mycobacterium tuberculosis 01.01.2013 Project funding (Div. I-III)
162641 Integrated investigation of the ESX-1 protein secretion system of Mycobacterium tuberculosis 01.01.2016 Project funding (Div. I-III)
133703 Host genomics of extreme phenotypes caused by common viral diseases: genome sequencing in children with severe respiratory infections 01.04.2011 SNSF Professorships
164174 From genome-derived knowledge to diagnostics for leprosy 01.01.2016 Brazil
135713 Innate defenses against retroelements 01.04.2011 Project funding (Div. I-III)
120035 Innate defenses against retroelements 01.04.2008 Project funding (Div. I-III)
118194 Determinants of social organisation in ant colonies 01.10.2007 Project funding (Div. I-III)
130287 The evolution of mammalian tissue transcriptomes 01.05.2010 Project funding (Div. I-III)
130326 The effect of sequence variation on chromatin structure and transcription 01.04.2010 Sinergia
122691 KRAB/KAP1 epigenetic regulation in the control of memory and emotional traits: from mice to humans. 01.12.2008 Sinergia
138346 Molecular genetics of retinitis pigmentosa: identification and functional analysis of new disease genes 01.10.2011 Project funding (Div. I-III)
128157 KRAB/KAP1 epigenetic regulation and pluripotent stem cell homeostasis 01.03.2010 NRP 63 Stem cells and regenerative medicine
125061 Structure-function analysis of the protein secretion system ESX-1 of Mycobacterium tuberculosis 01.04.2009 Project funding (Div. I-III)

-