Project

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Functional Inorganic Materials: Synthetic Strategies and Applications

English title Functional Inorganic Materials: Synthetic Strategies and Applications
Applicant Patzke Greta Ricarda
Number 133483
Funding scheme SNSF Professorships
Research institution Institut für Chemie B Universität Zürich
Institution of higher education University of Zurich - ZH
Main discipline Inorganic Chemistry
Start/End 01.05.2011 - 30.04.2013
Approved amount 793'217.00
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All Disciplines (2)

Discipline
Inorganic Chemistry
Material Sciences

Keywords (8)

nanomaterials; oxides; polyoxometalates; composite materials; drug delivery; synthetic techniques; in situ investigations; hydrothermal synthesis

Lay Summary (English)

Lead
Lay summary

Oxide materials are indispensable tools for a future nanotechnology and for the solution of  key contemporary research issues, such as water treatment, gas sensing and new energy sources. However, the way to oxide-based nanotechnological innovations is still challenging with respect to the controlled transformation of the multitude of oxide structures onto nanoscale dimensions. The present project is therefore focused on the targeted synthesis of oxide materials with high impact on current energy, environmental and health technology.

PART 1: Polyoxometalates - Crystal Engineering and Materials Development

Polyoxometalates (POMs) are a fascinating class of oxocluster materials with transition metal elements (preferably Mo, W and V) in their high oxidation states. POMs keep attracting worldwide research interest due to the multitude of their structural architectures and their impressive range of properties, such as catalytic activity, magnetism and bio-medical features (cf. PART 2). Over the past years, we have focused on the construction of large polyoxotungstates using lanthanoid cations as versatile structural linkers. The potential of systematic approaches still remains to be explored with polyoxomolybdate components that can offer an even more flexible coordination chemistry. Mixed metal W/Mo-POMs and related materials will be synthesized to open up new functionalization pathways for catalysis and medical applications.

PART 2: Nanostructured Composites

Hybrid materials are at the forefront of current research activities, because they integrate key properties of organic and inorganic compounds in a synergistic fashion. The combination of POMs with bio-macromolecules, such as chitosan and its derivatives, is a particularly interesting field: here, the antiviral, anticancer and antibacterial activity of POMs can be implemented into a biocompatible functional matrix. Carboxymethyl chitosan (CMC), for example, offers excellent drug carrier properties and biodegradability. PART 2 is thus focused on the synthesis of nanoscale composites through the encapsulation of bio-active POMs into CMC and related biopolymers in close connection with PART 1. In order to fully tap the medical application potential of POMs and their nanocomposites, their cellular uptake mechanisms will be studied for the development of new drug delivery strategies.

PART 3: Novel Synthetic Methods

The development of flexible, tunable and straightforward synthetic methods is essential for the nanotechnological implementation of oxide materials. Simultaneous control over structure, composition and morphology is requested for the targeted nanoscale synthesis of complex oxide materials which often provide the most interesting properties. We thus work at the frontiers of oxide synthesis: the nanoscale production of new and catalytically active W- and Mo-based oxide systems as well as of versatile nanostructured spinels will be explored with a wide arsenal of state-of-the-art synthetic techniques. The emerging nanoscale functional oxides will be tuned for environmentally important applications, e.g. photocatalytic wastewater treatment and water oxidation or miniaturized sensor technology. Furthermore, we aim for innovative mechanistic in situ studies of microwave-hydrothermal processes.

 

 

Direct link to Lay Summary Last update: 21.02.2013

Responsible applicant and co-applicants

Employees

Publications

Publication
Chitosan-Thioglycolic Acid as a Versatile Antimicrobial Agent
Geisberger Georg, Gyenge Emina Besic, Hinger Doris, Kaech Andres, Maake Caroline, Patzke Greta R. (2013), Chitosan-Thioglycolic Acid as a Versatile Antimicrobial Agent, in BIOMACROMOLECULES, 14(4), 1010-1017.
One-step hydrothermal synthesis of hierarchical Ag/Bi2WO6 composites: In situ growth monitoring and photocatalytic activity studies
Antonova Elena, Bensch Wolfgang, Patzke Greta R. (2013), One-step hydrothermal synthesis of hierarchical Ag/Bi2WO6 composites: In situ growth monitoring and photocatalytic activity studies, in SCIENCE CHINA-CHEMISTRY, 56(4), 435-442.
Trilacunary Keggin-Type POMs as Versatile Building Blocks for Lanthanoid Silicotungstates
Ni Lubin, Spingler Bernhard, Weyeneth Stephen, Patzke Greta R. (2013), Trilacunary Keggin-Type POMs as Versatile Building Blocks for Lanthanoid Silicotungstates, in EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, (10-11), 1681-1692.
One-step hydrothermal synthesis of hierarchical Ag/Bi2WO6 composites: In situ growth monitoring and photocatalytic activity studies
Zhou Y., Zhang Q., Lin Y., Antonova E., Bensch W., Patzke G. R. (2013), One-step hydrothermal synthesis of hierarchical Ag/Bi2WO6 composites: In situ growth monitoring and photocatalytic activity studies, in Science China Chemistry, 56, 435-442.
Hydrazine-Assisted Formation of Indium Phosphide (InP)-Based Nanowires and Core-Shell Composites
Patzke Greta R., Kontic Roman, Shiolashvili Zeinab, Makhatadze Nino, Jishiashvili David (2013), Hydrazine-Assisted Formation of Indium Phosphide (InP)-Based Nanowires and Core-Shell Composites, in MATERIALS, 6(1), 85-100.
Trimethyl and carboxymethyl chitosan carriers for bio-active polymer-inorganic nanocomposites
Geisberger Georg, Gyenge Emina Besic, Maake Caroline, Patzke Greta R. (2013), Trimethyl and carboxymethyl chitosan carriers for bio-active polymer-inorganic nanocomposites, in CARBOHYDRATE POLYMERS, 91(1), 58-67.
Bi2O3 or Bi6S2O15 nanowires? The role of templating inorganic additives in nanomaterials formation
Zhou Y, Patzke GR (2012), Bi2O3 or Bi6S2O15 nanowires? The role of templating inorganic additives in nanomaterials formation, in CRYSTENGCOMM, 14(3), 1161-1163.
Microwave-hydrothermal synthesis and characterization of nanostructured copper substituted ZnM2O4 (M = Al, Ga) spinels as precursors for thermally stable Cu catalysts
Conrad F, Massue C, Kuhl S, Kunkes E, Girgsdies F, Kasatkin I, Zhang BS, Friedrich M, Luo Y, Armbruster M, Patzke GR, Behrens M (2012), Microwave-hydrothermal synthesis and characterization of nanostructured copper substituted ZnM2O4 (M = Al, Ga) spinels as precursors for thermally stable Cu catalysts, in NANOSCALE, 4(6), 2018-2028.
New spinel oxide catalysts for visible-light-driven water oxidation
Conrad F, Bauer M, Sheptyakov D, Weyeneth S, Jaeger D, Hametner K, Car PE, Patscheider J, Gunther D, Patzke GR (2012), New spinel oxide catalysts for visible-light-driven water oxidation, in RSC ADVANCES, 2(7), 3076-3082.
Photocatalytic Composites of Silicone Nanofilaments and TiO2 Nanoparticles
Meseck Georg R., Kontic Roman, Patzke Greta R., Seeger Stefan (2012), Photocatalytic Composites of Silicone Nanofilaments and TiO2 Nanoparticles, in ADVANCED FUNCTIONAL MATERIALS, 22(21), 4433-4438.
New Perspectives on Polyoxometalate Catalysts: Alcohol Oxidation with Zn/Sb-Polyoxotungstates
Ni Lubin, Patscheider Joerg, Baldridge Kim K., Patzke Greta R. (2012), New Perspectives on Polyoxometalate Catalysts: Alcohol Oxidation with Zn/Sb-Polyoxotungstates, in CHEMISTRY-A EUROPEAN JOURNAL, 18(42), 13293-13298.
All-inorganic 1D chain-based architecture of a novel dimanganese-substituted Keggin polyoxotungstate
Car P.-E., Spingler B., Weyeneth S., Patscheider J., Patzke G. R. (2012), All-inorganic 1D chain-based architecture of a novel dimanganese-substituted Keggin polyoxotungstate, in Polyhedron, 52, 151-158.
Morphology control of BiVO4 photocatalysts: pH optimization vs. self-organization
Ressnig Debora, Kontic Roman, Patzke Greta R. (2012), Morphology control of BiVO4 photocatalysts: pH optimization vs. self-organization, in MATERIALS CHEMISTRY AND PHYSICS, 135(2-3), 457-466.
Photodynamic Mechanisms induced by a Combination of Hypericin and a Chlorin Based-Photosensitizer in Head and Neck Squamous Cell Carcinoma Cells
Besic Gyenge E., Lüscher D., Forny P., Antoniol M., Geisberger G., Walt H., Patzke G., Maake C. (2012), Photodynamic Mechanisms induced by a Combination of Hypericin and a Chlorin Based-Photosensitizer in Head and Neck Squamous Cell Carcinoma Cells, in Photochemistry and Photobiology, 89, 150-162.
1D- and 2D-architectures via self-assembly of the novel sandwich-type polyoxometalate [Zn2Sb2(B-alpha-ZnW9O34)2]14-
Ni L., Patzke G. R. (2012), 1D- and 2D-architectures via self-assembly of the novel sandwich-type polyoxometalate [Zn2Sb2(B-alpha-ZnW9O34)2]14-, in CrystEngComm, 14, 6778-6782.
Synthetic trends for BiVO4 photocatalysts: Molybdenum substitution vs. TiO2 and SnO2 heterojunctions
Kontic R, Patzke GR (2012), Synthetic trends for BiVO4 photocatalysts: Molybdenum substitution vs. TiO2 and SnO2 heterojunctions, in JOURNAL OF SOLID STATE CHEMISTRY, 189, 38-48.
Synthesis and characterization of open and sandwich-type polyoxometalates reveals visible-light-driven water oxidation via POM-photosensitizer complexes
Car PE, Guttentag M, Baldridge KK, Alberto R, Patzke GR (2012), Synthesis and characterization of open and sandwich-type polyoxometalates reveals visible-light-driven water oxidation via POM-photosensitizer complexes, in Green Chemistry, 14, 1680-1688.
Humidity sensing of bismuth phosphates
Sheng M, Gu L, Kontic R, Zhou Y, Zheng K, Chen G, Mo X, Patzke GR (2012), Humidity sensing of bismuth phosphates, in Sensors and Actuators B, 166-167, 642-649.
In Situ X-ray Absorption Spectroscopy/Energy-Dispersive X-ray Diffraction Studies on the Hydrothermal Formation of Bi2W1-xMoxO6 Nanomaterials
Zhou Y, Antonova E, Lin YH, Grunwaldt JD, Bensch W, Patzke GR (2012), In Situ X-ray Absorption Spectroscopy/Energy-Dispersive X-ray Diffraction Studies on the Hydrothermal Formation of Bi2W1-xMoxO6 Nanomaterials, in EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, (5), 783-789.
Oxide Nanomaterials: Synthetic Developments, Mechanistic Studies, and Technological Innovations
Patzke GR, Zhou Y, Kontic R, Conrad F (2011), Oxide Nanomaterials: Synthetic Developments, Mechanistic Studies, and Technological Innovations, in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 50(4), 826-859.
Self-assembly of dilacunary building blocks into high-nuclear [Ln(16)As(16)W(164)O(576)(OH)(8)(H2O)(42)](80-) (Ln = Eu-III, Gd-III, Tb-III, Dy-III, and Ho-III) polyoxotungstates
Hussain F, Patzke GR (2011), Self-assembly of dilacunary building blocks into high-nuclear [Ln(16)As(16)W(164)O(576)(OH)(8)(H2O)(42)](80-) (Ln = Eu-III, Gd-III, Tb-III, Dy-III, and Ho-III) polyoxotungstates, in CRYSTENGCOMM, 13(2), 530-536.
Humidity sensors based on ZnO/TiO2 core/shell nanorod arrays with enhanced sensitivity
Gu L, Zheng KB, Zhou Y, Li J, Mo XL, Patzke GR, Chen GR (2011), Humidity sensors based on ZnO/TiO2 core/shell nanorod arrays with enhanced sensitivity, in SENSORS AND ACTUATORS B-CHEMICAL, 159(1), 1-7.
Targeted Delivery of Polyoxometalate Nanocomposites
Geisberger G, Paulus S, Gyenge EB, Maake C, Patzke GR (2011), Targeted Delivery of Polyoxometalate Nanocomposites, in SMALL, 7(19), 2808-2814.
Lanthanoid-Containing Open Wells Dawson Silicotungstates: Synthesis, Crystal Structures, and Properties
Ni LB, Hussain F, Spingler B, Weyeneth S, Patzke GR (2011), Lanthanoid-Containing Open Wells Dawson Silicotungstates: Synthesis, Crystal Structures, and Properties, in INORGANIC CHEMISTRY, 50(11), 4944-4955.
Morphology Control of BiVO4 Photocatalysts: pH Optimization vs. Self-Organization
Ressnig D, Kontic R, Patzke GR, Morphology Control of BiVO4 Photocatalysts: pH Optimization vs. Self-Organization, in Materials Chemistry and Physics.
Synthesis, characterization and bioimaging of fluorescent labeled polyoxometalates
Geisberger G., Besic Gyenge E., Hinger D., Bösiger P., Maake C., Patzke G. R., Synthesis, characterization and bioimaging of fluorescent labeled polyoxometalates, in Dalton Transactions.

Collaboration

Group / person Country
Types of collaboration
Southwest Petroleum University China (Asia)
- in-depth/constructive exchanges on approaches, methods or results
- Publication

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
Helmholtz-Zentrum Dresden-Rossendorf, Kolloquium 21.03.2013 Dresden/Germay
ICACC 2013 27.01.2013 Daytona Beach/Florida
The 3rd International Solvothermal and Hydrothermal Association Conference 13.01.2013 Austin, TX/USA
Frontiers in Metal-Oxide Cluster Science 2012 18.11.2012 Lanzarote/Spain
ETH Institute of Energy Technology, Colloquium 24.10.2012 Zürich/CH
16. Vortragstagung der GDCh Fachgruppe Festkörperchemie und Materialforschung, Darmstadt 17.09.2012 Darmstadt/Germany
SCS Fall Meeting 2012 13.09.2012 Zürich/Switzerland
ZFM Colloquium 09.07.2012 Hannover/Germany
SPS Annual Meeting 2012 21.06.2012 Zürich/CH
SPEA7 (7th European Meeting on Solar Chemistry and Photocatalysis) 17.06.2012 Porto/Portugal
2012 Inorganic Chemistry Gordon Research Conference 17.06.2012 Biddeford/USA
WCAM 2012: 1st World Annual Advanced Materials Conference 06.06.2012 Beijing/China
45. Jahrestreffen Deutscher Katalytiker 14.03.2012 Weimar/D
21. DECHEMA Diskussionstagung "Anorganisch-Technische Chemie", Frankfurt/Main 01.03.2012 Frankfurt/Main
2nd European Symposium on Photocatalysis JEP 2011 29.09.2011 Bordeaux/France
SCS Fall Meeting 2011 09.09.2011 Lausanne/CH
GDCh Wissenschaftsforum Chemie, Bremen 04.09.2011 Bremen/Germany
15th International Conference on Biological Inorganic Chemistry (ICBIC), Vancouver/Canada 07.08.2011 Vancouver/Canada
ICMAT 2011, International Conference on Materials for Advanced Technologies 26.06.2011 Singapore
1st Swiss Heterogeneous Catalysis Meeting 16.06.2011 Grindelwald/CH
Young Faculty Meeting 2011 16.06.2011 Bern/CH
Anorganisch-chemisches Kolloquium der Universität Bayreuth 17.05.2011 Bayreuth/Germany


Associated projects

Number Title Start Funding scheme
114711 Targeted Synthesis of Functional Inorganic Materials 01.05.2007 SNSF Professorships
144964 Upgrade of the UZH NMR Core Facility 01.12.2012 R'EQUIP

Abstract

1. SUMMARY AND GOALS OF THE PROPOSED RESEARCHOxide materials are indispensable tools for a future nanotechnology and for the solution of our most urgent environmental and energy issues: their wide range of applications encompasses catalysis, battery technology, sensors, superconducting devices, new displays and light sources or diagnostic nano-medicine - just to mention a few. However, one major roadblock remains to be overcome on the way to oxide-based nanotechnological innovations - and this is the controlled transformation of the multitude of structural oxide varieties onto nanoscale dimensions. The present project is therefore focused on the targeted synthesis of oxide materials with a high impact on current energy, environmental and health technology.PART 1: Polyoxometalates - Crystal Engineering and Materials DevelopmentPolyoxometalates (POMs) are a fascinating class of oxocluster materials with transition metal elements (preferably Mo, W and V) in their high oxidation states. POMs come along in a multitude of structural architectures that keep attracting worldwide research interest. This structural diversity leads to an impressive range of POM properties, such as catalytic activity, magnetism and bio-medical features (cf. PART 2). Over the past years, we have focused on the construction of large polyoxotungstates using high-coordinated and oxophilic lanthanoid cations as structural linkers. However, the potential of this approach still remains to be explored with polyoxomolybdate components that can offer an even more flexible coordination chemistry. Their combination with lanthanoid linkers will open up new perspectives in the chemistry of mixed metal W/Mo-POMs and their functionalization for medicinal applications.PART 2: Nanostructured CompositesHybrid materials are in the forefront of current research activities, because they integrate key properties of organic and inorganic compounds in a synergistic fashion. The combination of POMs with bio-macromolecules, such as chitosan and its derivatives, is a particularly interesting field: here, the antiviral, anticancer and antibacterial activity of POMs can be merged with a biocompatible functional matrix that offers wound-healing and tissue-engineering properties. PART 2 is thus focused on the synthesis of nanoscale composites through the encapsulation of antiviral POMs into carboxymethyl chitosan (CMC) and related biopolymers in close connection with PART 1. Our recent biochemical investigations on antiviral POMs inspired us to fully tap the medicinal potential of POMs by studying their cellular uptake mechanisms for the development of new drug delivery strategies.PART 3: Novel Synthetic MethodsThe development of flexible, tunable and straightforward synthetic methods is essential for the nanotechnological implementation of oxide materials. However, the targeted nanoscale synthesis of complex oxide materials - which often provide the most interesting properties - remains a considerable challenge that requires simultaneous control over structure, composition and morphology. We thus work at the frontiers of oxide synthesis: the nanoscale production of new and catalytically active W- and Mo-based oxide systems as well as versatile nanostructured spinels will be explored with a wide arsenal of state-of-the-art synthetic techniques (from microwave-hydrothermal over sonochemical reactions to flame syntheses). The emerging nanoscale functional oxides will be tuned for environmentally important applications, e.g. photocatalysis and miniaturized sensor technology. Furthermore, we aim for pioneering mechanistic in situ studies of microwave-hydrothermal processes.
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