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NCCR TransCure: From transport physiology to identification of therapeutic targets (phase I)

English title NCCR TransCure - From transport physiology to identification of therapeutic targets
Applicant Hediger Matthias A.
Number 125762
Funding scheme National Centres of Competence in Research (NCCRs)
Research institution Institut für Biochemie und Molekulare Medizin Universität Bern
Institution of higher education University of Berne - BE
Main discipline Physiology : other topics
Start/End 01.11.2010 - 31.10.2014
Approved amount 14'155'000.00
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All Disciplines (2)

Discipline
Physiology : other topics
Pharmacology, Pharmacy

Keywords (18)

structural biology; neurophysiology; endocrinology; pharmacology; gynecology; medicinal chemistry; heart; lung; kidney ; brain; liver; bone ; mammary gland; intestine ; drug design; channel ; nutrition; transport

Responsible applicant and co-applicants

Associated projects

Number Title Start Funding scheme
146363 Chemical Space as a Source for New Drugs 01.05.2013 Project funding (Div. I-III)
178998 Chemical Space Design of Small Molecules and Peptides 01.04.2018 Project funding (Div. I-III)
149958 Regulation and Role of ABCA1-mediated Cholesterol Transfer in the Human Placenta in Health and Disease: Protecting the Fetal Environment and/or Maintaining Placental Endocrine Function? 01.05.2014 Project funding (Div. I-III)
145023 Advanced Imaging System for Biomolecular Crystallization Screening 01.12.2012 R'EQUIP
160620 NCCR TransCure: From transport physiology to identification of therapeutic targets (phase II) 01.11.2014 National Centres of Competence in Research (NCCRs)
162581 Structure and supramolecular organization of membrane transport proteins 01.12.2015 Project funding (Div. I-III)
164092 Upgrade of a Titan Krios electron cryo-microscope for single particle analysis and tomography 01.12.2015 R'EQUIP
160782 Store-operated calcium channels in health and disease 01.10.2015 Sinergia
144195 Molecular Mechanisms of Canalicular Bile Formation: Role of Novel Phospholipid Flippases and Drug Uptake Mechanisms 01.05.2013 Project funding (Div. I-III)
144168 Structure and supramolecular organization of membrane transport proteins 01.11.2012 Project funding (Div. I-III)
157704 Direct electron detector and phase plate for cryo-transmission electron microscopy of biological samples 01.12.2014 R'EQUIP
156376 Elucidating the role of human zinc transporters in health and disease 01.05.2015 Project funding (Div. I-III)
150766 UV-Fluorescence microscopy based incubation and imaging platform for protein and nucleic acid crystals 01.12.2013 R'EQUIP
170808 Acquisition of a Talos Arctica transmission electron microscope for single particle analysis and cryo-tomography 01.05.2017 R'EQUIP
139231 Advancement of functional genomics research at the University of Bern by extension of LC-MS platform 01.07.2012 R'EQUIP
166563 Role of Membrane Lipid Environment on the Transport Acitivity of Hepatocellular Organic Anion Transporters 01.09.2016 Project funding (Div. I-III)
189111 Structural and mechanistic studies of liver ABC transporters 01.10.2019 Project funding (Div. I-III)
130001 The GDB approach to drug discovery 01.05.2010 Project funding (Div. I-III)
165997 Exploiting and Extending GDB for Drug Discovery 01.05.2016 Project funding (Div. I-III)

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