criticaly ill patients; sepsis; phagocytosis; opsonins; alarmins; toll-like receptors; Innate immunity
Tissières Pierre, Ochoda Agnieszka, Dunn-Siegrist Irène, Drifte Geneviève, Morales Michel, Pfister Riccardo, Berner Michel, Pugin Jérôme (2012), Innate immune deficiency of extremely premature neonates can be reversed by interferon-γ., in PloS one
, 7(3), 32863-32863.
Charles Pierre-Emmanuel, Tissières Pierre, Barbar Saber Davide, Croisier Delphine, Dufour Julien, Dunn-Siegrist Irène, Chavanet Pascal, Pugin Jérôme (2011), Mild-stretch mechanical ventilation upregulates toll-like receptor 2 and sensitizes the lung to bacterial lipopeptide., in Critical care (London, England)
, 15(4), 181-181.
Tissières Pierre, Araud Tanguy, Ochoda Agnieszka, Drifte Geneviève, Dunn-Siegrist Irène, Pugin Jérôme (2009), Cooperation between PU.1 and CAAT/enhancer-binding protein beta is necessary to induce the expression of the MD-2 gene., in The Journal of biological chemistry
, 284(39), 26261-72.
Tissières Pierre, Pugin Jérôme (2009), The role of MD-2 in the opsonophagocytosis of Gram-negative bacteria., in Current opinion in infectious diseases
, 22(3), 286-91.
Brégeon Fabienne, Papazian Laurent, Delpierre Stéphane, Kajikawa Osamu, Payan Marie-José, Martin Thomas R, Kipson Nathalie, Pugin Jérôme (2008), Role of proinflammatory activity contained in gastric juice from intensive care unit patients to induce lung injury in a rabbit aspiration model., in Critical care medicine
, 36(12), 3205-12.
Pugin Jérôme, How tissue injury alarms the immune system and causes a systemic inflammatory response syndrome, in Annals of Intensive Care
, in press.
Dunn-Siegrist Irène, Tissières Pierre, Drifte Geneviève, Bauer Jacques, Moutel Stéphane, Pugin Jérôme, Toll-like receptor activation of human cells by synthetic triacylated lipid A-like molecules., in The Journal of biological chemistry
, in press.