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R'Equip - Amélioration de deux spectromètres RMN 9.4T par des consôles digitales

English title R'Equip - Upgrade of two 9.4T NMR spectrometers with fully digital consoles
Applicant Helm Lothar
Number 121262
Funding scheme R'EQUIP
Research institution Laboratoire de chimie inorganique et bioinorganique EPFL - SB - ISIC - LCIB
Institution of higher education EPF Lausanne - EPFL
Main discipline Organic Chemistry
Start/End 01.07.2008 - 30.06.2009
Approved amount 200'000.00
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All Disciplines (2)

Discipline
Organic Chemistry
Inorganic Chemistry

Keywords (7)

synthesis; structure; NMR spectrometers; multi-dimensional NMR; solvent suppression; organic synthesis; inorganic synthesis

Lay Summary (English)

Lead
Lay summary
This proposal, submitted by the NMR service of the Institute of Chemical Sciences and Engineering (ISIC) of EPFL, aims to upgrade two old NMR spectrometers by replacing their consoles (transmitters, receivers, associated hardware, and computers). The two 9.4 T standard bore superconducting magnets have characteristics still comparable to modern magnets and will therefore be kept. The pulse generation and the signal treatment of the new consoles will be fully digital leading to improved frequency and phase stability and time resolution. Both new consoles will be equipped with two equivalent fully digital frequency channels and a unit to generate z-gradients of the magnetic field. Modern NMR experiments using for example effective solvent suppression, magnetic field gradients and shaped excitation pulses will finally be possible on the new instruments. New state-of-the-art computers will use recently developed programs to pilot the spectrometer and to allow data evaluation. Organic and inorganic synthesis is relying on permanent control leading to a need of quickly available and reliable NMR measurements. To allow fully automatic measurements with high sample throughput a new multinuclear probe with automatic tuning and matching capability (together with an existing sample changer) will be installed on one of the spectrometers. The new upgraded spectrometers will allow satisfying the increasing demand on modern one and two dimensional NMR spectroscopy at Institute of Chemical Sciences and Engineering and other institutes at EPFL asking for NMR service. Furthermore, companies mainly in the surrounding of Lausanne and the in canton of Valais will also take profit of the new possibilities EPFL is offering to them.
Direct link to Lay Summary Last update: 21.02.2013

Responsible applicant and co-applicants

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Abstract

This proposal, submitted by the NMR service of the Institute of Chemical Sciences and Engineering (ISIC) of EPFL, aims to upgrade two old NMR spectrometers by replacing their consoles (transmitters, receivers, associated hardware, and computers). The two 9.4 T standard bore superconducting magnets have characteristics still comparable to modern magnets and will therefore be kept. The pulse generation and the signal treatment of the new consoles will be fully digital leading to improved frequency and phase stability and time resolution. Both new consoles will be equipped with two equivalent fully digital frequency channels and a unit to generate z-gradients of the magnetic field. Modern NMR experiments using for example effective solvent suppression, magnetic field gradients and shaped excitation pulses will finally be possible on the new instruments. New state-of-the-art computers will use recently developed programs to pilot the spectrometer and to allow data evaluation. Organic and inorganic synthesis is relying on permanent control leading to a need of quickly available and reliable NMR measurements. To allow fully automatic measurements with high sample throughput a new multinuclear probe with automatic tuning and matching capability (together with an existing sample changer) will be installed on one of the spectrometers. The new upgraded spectrometers will allow satisfying the increasing demand on modern one and two dimensional NMR spectroscopy at Institute of Chemical Sciences and Engineering and other institutes at EPFL asking for NMR service. Furthermore, companies mainly in the surrounding of Lausanne and the in canton of Valais will also take profit of the new possibilities EPFL is offering to them.
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