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Elucidation of the molecular regulation mechanisms of auxin flow by KANADI, Class III HD-Zip, and YABBY class patterning genes and their impact on auxin response factor action during early embryo development of Arabidopsis thaliana

English title Elucidation of the molecular regulation mechanisms of auxin flow by KANADI, Class III HD-Zip, and YABBY class patterning genes and their impact on auxin response factor action during early embryo development of Arabidopsis thaliana
Applicant Brand Lukas
Number 118806
Funding scheme Fellowships for prospective researchers
Research institution School of Biological Sciences Monash University
Institution of higher education Institution abroad - IACH
Main discipline Embryology, Developmental Biology
Start/End 01.01.2008 - 30.06.2009
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All Disciplines (5)

Discipline
Embryology, Developmental Biology
Molecular Biology
Cellular Biology, Cytology
Genetics
Biochemistry

Keywords (6)

Arabidopsis; embryo development; auxin; patterning genes; auxin response factors (ARF); whole genome tiling-array

Lay Summary (English)

Lead
Lay summary
Plant shape is an important trait for plant breeding and agriculture. In the past few years, three families of genes have been found to be crucial for plant organ development in terms of polarity. Thus, those genes mark different domains within the developing organ such as a leave or flower to determine cell identities that eventually turn into the visible, distinct architecture of plant organs in later development. Plants produce all major organs from small populations of cells contained within two meristems located at the root and shoot tip, respectively. Sites of organ emergence have been found to coincide with local concentration maxima of the actively transported plant hormone auxin in the meristem. Plants are growing by iterative development from meristems after germination.
Despite the significant progress made recently on auxin transport mediators, understanding the process of the flux itself, it remains largely unknown what molecular mechanisms determine the overall auxin distribution pattern.
My work aims to link the action between the distribution and flux of auxin and the activity of the polarity gene families during embryo development in Arabidopsis thaliana. Using inducible lines of patterning genes and assessing the genome wide transcription profiles, my research is uncovering linking elements involved in the crosstalk between polarity transcription factors and proteins known to direct the flux of auxin. The transcriptional profiling has been done successfully. Currently I am performing further experiments to confirm the identified candidate genes and describe their implication in the cross-talk of patterning genes and auxin-flux mediators.


Direct link to Lay Summary Last update: 21.02.2013

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