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Computer-assisted cognitive remediation program for adolescents with mental disorders. Measure of cognitive and clinical efficacy

English title Computer-assisted cognitive remediation program for adolescents at high risk of psychosis or with psychotic disorders. Measure of cognitive and clinical efficacy
Applicant Holzer Laurent
Number 112160
Funding scheme Project funding (Div. I-III)
Research institution Centre Thérapeutique de Jour pour Adolescents
Institution of higher education University of Lausanne - LA
Main discipline Neurology, Psychiatry
Start/End 01.09.2006 - 30.11.2009
Approved amount 211'118.00
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All Disciplines (2)

Discipline
Neurology, Psychiatry
Rehabilitation

Keywords (6)

adolescence; cognitive impairment; cognitive remediation; computer assisted cognitive remediation; psychopathology; psychiatric disorders

Lay Summary (English)

Lead
Lay summary
Cognitive impairments are frequent among adolescents with psychotic disorders and are also observed among adolescents at high risk of psychosis. These deficits precede the onset of schizophrenia spectrum disorders and may worsen in the early course of the illness. Cognitive impairment hampers learning processes which may hinder school or academic achievements and account for functional outcome in major psychiatric disorders. Cognitive remediation programs are available in computerized versions. In psychiatry, such programs have proved to be an effective complement to usual treatments for children with attention deficit hyperactivity disorder (ADHD) and for adults with severe psychiatric disorders (e.g. chronic schizophrenia). Given a greater cerebral plasticity, adolescents are likely to benefit all the more from cognitive remediation and computerized programs suit this population well. The efficacy of computer-assisted cognitive remediation (CACR) in adolescents has not yet been established. Although frequently assumed, it is unclear whether improvement in basic cognitive functions is likely to alleviate or cure clinical symptoms.The aim of the present study is to ascertain the efficacy of a CACR program for adolescents at high risk of psychosis or with psychotic disorders and cognitive impairments, and to measure the impact of CACR on clinical symptomatology, self-esteem and global functioning. It will also allow assessing the attractiveness and observance of a CACR program in a clinical adolescent population.
Direct link to Lay Summary Last update: 21.02.2013

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