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Synapses let loose for a change: inhibitory synapse pruning throughout experience-dependent cortical plasticity.

Type of publication Not peer-reviewed
Publikationsform Review article (non peer-reviewed)
Publication date 2012
Author Gambino Frédéric, Holtmaat Anthony,
Project Long-term potentiation and the modification of synaptic structures in vivo
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Review article (non peer-reviewed)

Journal Neuron
Volume (Issue) 74(2)
Page(s) 214 - 7
Title of proceedings Neuron
DOI 10.1016/j.neuron.2012.04.005


In this issue of Neuron, Chen et al. (2012) and van Versendaal et al. (2012) used fluorescently tagged gephyrin to track inhibitory synapses in the mouse visual cortex in vivo. Their studies show that visual experience-dependent plasticity is associated with clustered and location-specific pruning of inhibitory synapses.