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Nitric Oxide-Scavenging Activity Of In Vitro Cultured Balkan Medicinal And Aromatic Plants

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Publication date 2013
Author Mehandzhiyski A Batovska D Dimitrov D Evstatieva L Danova K,
Project PhytoBalk
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Original article (peer-reviewed)

Journal BJAS Bulgarian Journal of Agricultural Science
Volume (Issue) 19(2)
Page(s) 31 - 34
Title of proceedings BJAS Bulgarian Journal of Agricultural Science

Open Access

Type of Open Access Website


Methanolic extracts from the aerial and root parts of in vitro cultured Artemisia alba and the aerials of in vitro cultured Clinopodium vulgare, Hypericum tetrapterum, H. richeri and the endemic H. rumeliacum were evaluated for their nitric oxide scavenging capacities. Extracts of H. rumeliacum, H. richeri and H. tetrapterum exhibited remarkably higher activity (0.18, 0.17 and 0.97–1, respectively) compared to C. vulgare and A. alba (SC50 = 3.45, 2.93 and 2.62–1, respectively). Vitamin C (a reference compound), exhibited activity of 0.26–1. The presented results are indicative of the high therapeutic potential of the extracts derived from the in vitro cultured plants and are a good basis for further more detailed research.