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A mechanism for eye position effects on spontaneous nystagmus.

Type of publication Not peer-reviewed
Publikationsform Original article (non peer-reviewed)
Publication date 2012
Author Khojasteh Elham, Bockisch Christopher J, Straumann Dominik, Hegemann Stefan C A,
Project Three-dimensional kinematical analysis of ocular motor disorders in humans
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Original article (non peer-reviewed)

Journal Conf Proc IEEE Eng Med Biol Soc
Page(s) 3572 - 5
Title of proceedings Conf Proc IEEE Eng Med Biol Soc

Abstract

In acute stages of unilateral vestibular deficit, the imbalanced tonic activity on vestibular afferents evokes spontaneous nystagmus. The slow-phase velocity of this nystagmus varies with eye position, such that it is smaller when looking in the direction of slow-phases. The neural mechanism for this behavior is still not understood. Here, using a simple control system model, we show that plausible changes in the neural responses within the central vestibulo-ocular reflex pathway are adequate to cause eye position dependent effects in the nystagmus pattern. The proposed transformations in population response functions could happen immediately following a lesion and can be useful to stabilize gaze in part of the gaze field
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