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The CONTIN algorithm and its application to determine the size distribution of microgel suspensions

Type of publication Peer-reviewed
Publikationsform Original article (peer-reviewed)
Author Scotti Andrea, Liu W., Hyatt J.S., Herman E.S., Choi H.S., Kim J.W., Lyon L.A., Gasser Urs, Fernandez-Nieves Alberto,
Project Heterogenous nucleation and crystal growth of colloidal model-systems on curved surfaces
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Original article (peer-reviewed)

Journal The Journal of Chemical Physics
Volume (Issue) 142
Page(s) 234905
Title of proceedings The Journal of Chemical Physics
DOI 10.1063/1.4921686


We review a powerful regularization method, known as CONTIN, for obtaining the size distribution of colloidal suspensions from dynamic light scattering data. We show that together with the so-called L-curve criterion for selecting the optimal regularization parameter, the method correctly describes the average size and size distribution of microgel suspensions independently characterized using small-angle neutron scattering. In contrast, we find that when using the default regularization process, where the regularizer is selected via the “probability to reject” method, the results are not as satisfactory.