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Innovative natural fungicide to control Botrytis grey mold on fruits: new epidemiological insights.

English title Innovative natural fungicide to control Botrytis grey mold on fruits: new epidemiological insights.
Applicant Dubey Olga
Number 177280
Funding scheme Bridge - Proof of Concept
Research institution
Institution of higher education Research Institutes Agroscope - AGS
Main discipline Agricultural and Forestry Sciences
Start/End 01.09.2017 - 28.02.2019
Approved amount 95'000.00
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All Disciplines (4)

Agricultural and Forestry Sciences
Cellular Biology, Cytology
Molecular Biology

Keywords (5)

Agriculture; Natural solutions; Fungicides; Food wastage; AgroSustain

Lay Summary (French)

AgroSustain développe et met sur le marché des solutions naturelles pour arrêter et prévenir le développement de moisissures sur les fruits et légumes frais.
Lay summary

USD 60 milliards de pertes de fruits et légumes en post-récolte sont causés par des champignons pathogènes qui, en outre, peuvent produire des métabolites toxiques pour l'homme, par exemple l'aflatoxine - cancérigène toxique produit par les espèces du genre Aspergillus. A ce jour, il n'existe sur le marché aucun traitement efficace, économique et naturel contre les moisissures.


AgroSustain est une spin-off de l'Université de Lausanne qui a identifié un grand nombre de composés antifongiques d'origine végétale. AgroShelf+, le premier produit en cours de développement, est un traitement efficace, inspiré des plantes, contre une large gamme d'agents pathogènes fongiques d'importance agronomique (plus de 20 espèces de champignons pathogènes). L'objectif d'AgroShelf+ est de prolonger d'au moins une semaine la durée de conservation des cultures infectées par des moisissures.


L'application du produit AgroShelf+ générera les avantages suivants pour les détaillants et distributeurs en alimentation :

1.  Réduction des pertes alimentaires après récolte de 80%

2.  Haute qualité alimentaire sans résidus chimiques

3.  Satisfaction des consommateurs

Direct link to Lay Summary Last update: 05.05.2019

Responsible applicant and co-applicants



Group / person Country
Types of collaboration
Gaëtan Glauser at the platform of analytical chemistry at the university of Neuchatel. Switzerland (Europe)
- Research Infrastructure

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
Agroscope PhD/Postdoc Symposium Poster The next generation natural fungicides to maintain low levels of fungal pathogens in a sustainable manner 13.09.2018 Agroscope Reckenholz Reckenholzstrasse 191 8046 Zürich , Switzerland Dubey Olga;

Knowledge transfer events

Active participation

Title Type of contribution Date Place Persons involved
Climate Show Talk 13.02.2019 Lausanne, Switzerland Dubey Olga;
Fruit Logistica, Berlin Performances, exhibitions (e.g. for education institutions) 05.02.2019 Berlin, Germany Dubey Olga;
Innosuisse courese, business concept Talk 24.01.2019 Basel, Switzerland Dubey Olga;
Swiss Startup days Talk 20.09.2018 Bern, Switzerland Dubey Olga;

Communication with the public

Communication Title Media Place Year
Media relations: print media, online media Multiple articles International 2018


Title Year
Forbes 30 Under 30, Geneva Sustainability award Dalle Molle Foundation for Quality of Life IMD startup competition, 2019 >>venture>> Top 4 2019


Title Date Number Inventor Owner
Fungicides to prevent and control fungal pathogens 07.04.2018 EP18182433


Fatty acids (FA) are known to be one of the major storage forms of carbon in living organisms, which are precursors for some plant hormones such as jasmonate (JA) and major building compounds of the membrane bilayer. During my PHD, I identified a new role of fatty acids in induction of plant resistance to B. cinerea. It is a nectrotrophic fungal pathogen that affects a broad range of cultivated and ornamental plants and causes serious agricultural loss each year (Jarwis, 1977). In this work, I will develop a new biofungicide based on the fungitoxic molecule identified from the Arabidopsis plants deficient in fatty acids. Two cultivars of Vitis vinifera (wine grape), Fragaria × ananassa (strawberry) and Solanum lycopersicum (tomato), displaying different susceptibility to B. cinerea will be used as model plants for biofungicide optimisations. Product concentration will be based on the results of fungicide sensitivity assays. Pre-formulation trials will be assessed against the two other major fungal pathogens of grapevine, i.e. the ectophytic powdery mildew (Erysiphe necator) and downy mildew (Plasmopora viticola). The second part of this project will be to identify other potential fungitoxic compounds from the plants that were shown to have B. cinerea resistance and bringing them to the market by developing efficient and low energy cost biological fungicides for farmers needs. The outcome of this project will be development of the new environmental friendly fungicide that potentially can lead to strong reduction in yield lost due to B. cinerea that could be applied in the agricultural fields and launching a start up “AgroSustain” at the end of Bridge funding.