Capelli Paolo, Pivetta Chiara, Soledad Esposito Maria, Arber Silvia (2017), Locomotor speed control circuits in the caudal brainstem., in
Nature, 551(7680), 373-377.
Baek Myungin, Pivetta Chiara, Liu Jeh-Ping, Arber Silvia, Dasen Jeremy S (2017), Columnar-Intrinsic Cues Shape Premotor Input Specificity in Locomotor Circuits., in
Cell reports, 21(4), 867-877.
Wu Jinjin, Capelli Paolo, Bouvier Julien, Goulding Martyn, Arber Silvia, Fortin Gilles (2017), A V0 core neuronal circuit for inspiration., in
Nature communications, 8(1), 544-544.
Arber Silvia (2017), Organization and function of neuronal circuits controlling movement., in
EMBO molecular medicine, 9(3), 281-284.
Ruder Ludwig, Takeoka Aya, Arber Silvia (2016), Long-Distance Descending Spinal Neurons Ensure Quadrupedal Locomotor Stability., in
Neuron, 92(5), 1063-1078.
Fleming Michael S, Li Jian J, Ramos Daniel, Li Tong, Talmage David A, Abe Shin-Ichi, Arber Silvia, Luo Wenqin (2016), A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles., in
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(40), 10337-10355.
Tovote Philip, Esposito Maria Soledad, Botta Paolo, Chaudun Fabrice, Fadok Jonathan P, Markovic Milica, Wolff Steffen B E, Ramakrishnan Charu, Fenno Lief, Deisseroth Karl, Herry Cyril, Arber Silvia, Lüthi Andreas (2016), Midbrain circuits for defensive behaviour., in
Nature, 534(7606), 206-12.
Esposito Maria S, Arber Silvia (2016), Motor Control: Illuminating an Enigmatic Midbrain Locomotor Center., in
Current biology : CB, 26(7), 291-3.
Satoh Daisuke, Pudenz Christiane, Arber Silvia (2016), Context-Dependent Gait Choice Elicited by EphA4 Mutation in Lbx1 Spinal Interneurons., in
Neuron, 89(5), 1046-58.
Basaldella Emanuela, Takeoka Aya, Sigrist Markus, Arber Silvia (2015), Multisensory Signaling Shapes Vestibulo-Motor Circuit Specificity., in
Cell, 163(2), 301-12.
Adamantidis Antoine, Arber Silvia, Bains Jaideep S, Bamberg Ernst, Bonci Antonello, Buzsáki György, Cardin Jessica A, Costa Rui M, Dan Yang, Goda Yukiko, Graybiel Ann M, Häusser Michael, Hegemann Peter, Huguenard John R, Insel Thomas R, Janak Patricia H, Johnston Daniel, Josselyn Sheena A, Koch Christof, Kreitzer Anatol C, Lüscher Christian, Malenka Robert C, Miesenböck Gero, Nagel Georg, Roska Botond, Schnitzer Mark J, Shenoy Krishna V, Soltesz Ivan, Sternson Scott M, Tsien Richard W, Tsien Roger Y, Turrigiano Gina G, Tye Kay M, Wilson Rachel I (2015), Optogenetics: 10 years after ChR2 in neurons-views from the community., in
Nature neuroscience, 18(9), 1202-12.
Goetz Cyrill, Pivetta Chiara, Arber Silvia (2015), Distinct limb and trunk premotor circuits establish laterality in the spinal cord., in
Neuron, 85(1), 131-44.
The aim of our research is to unravel the organization and function of neuronal circuits controlling motor behavior. Movement is the common behavioral output of all CNS activity, yet how different movement patterns emerge and are regulated at the level of precisely connected neuronal circuits in an animal is currently poorly understood. In the BoE extension of my current SNF grant, we would like to exploit how motor output pathways orchestrate the precise control of motor output regulation in the spinal cord in intact animals, and how this process is influenced by sensory feedback circuits from muscles. This work lays the foundation for a research direction addressing how these identified neuronal circuit elements respond to spinal cord injury. We are convinced that together, these experiments will help to reveal general principles governing neuronal circuit organization at the level of identified neuronal subpopulations involved in motor control, as well as determine the factors influencing motor circuit reorganization after injury.