Project

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Elastography: Imaging Soft Tissue Elasticity

Applicant Goksel Orcun
Number 150620
Funding scheme SNSF Professorships
Research institution Computer Vision Laboratory ETH Zürich
Institution of higher education ETH Zurich - ETHZ
Main discipline Information Technology
Start/End 01.08.2014 - 31.07.2018
Approved amount 1'635'798.00
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All Disciplines (3)

Discipline
Information Technology
Mechanical Engineering
Cancer

Keywords (10)

medical imaging; elastography; ultrasound; biomechanics; viscoelasticity; elastic modulus; finite element method; inverse problem; cancer; tumor

Lay Summary (German)

Lead
Seit Jahrhunderten wird Gewebeelastizität in der Medizin als ein Hinweis von Gewebeanomalien verwendet. Noch heute ist die Abtastung von Brust oder Prostata die häufigste klinische Untersuchungsmethode die in der Krebsvorsorge für diese anatomischen Strukturen angewendet wird. Elastographie ist eine aufstrebende Technik zur Ermittlung der Gewebeelastizität. Dieses Projekt zielt darauf ab, einige der noch offenen Fragen bei der Erzeugung von Ultraschallelastographiebildern zu klären. Gleichzeitig wird die Entwicklung von neuartigen Datenerfassung- und Analysetechniken für fortgeschrittene Bildgebungsanwendungen vorangetrieben werden.
Lay summary
Inhalt und Ziel des Forschungsprojekts

Elastographie ist eine aufstrebende Technik zur Ermittlung der Gewebeelastizität, die auf die Beobachtung und Analyse der Verformung von inneren Geweben in Ultraschall- oder Magnetresonanztomographie Bildreihen beruht. Die Ultraschallelastographie hat sich als besonders wichtige und weitverbreitete Technik erwiesen, da Ultraschalldaten in Echtzeit erfasst werden, die Technik auf nichtionisierender Strahlung basiert und die Anwendung kostengünstig ist.  Die Elastographie hat grosses Potential bei der Diagnose und Therapieplanung, da Pathologien wie Tumore oder Leberzirrhosen oft härter sind als das umgebende Gewebe.  Die Technik kann ferner auch zur Charakterisierung und Segmentierung von anatomischen Strukturen mit unterschiedlichen mechanischen Eigenschaften, z.B. Analyse von arteriellen Plaques, angewendet werden.  Trotz aller dieser Vorteile, hat die Elastographie noch nicht ihr volles Potential in der klinischen Anwendung erreicht.  Mehrere verschiedene methodische Ansätze auf diesem Gebiet sind noch nicht voll ausgereift und es besteht die Notwendigkeit zur Weiterentwicklung von robusteren Methoden zur Bestimmung der Gewebeelastizität in einer präziesen, schnellen und reproduzierbaren Weise. Dieses Projekt zielt darauf ab, einige der noch offenen Fragen bei der Erzeugung von Ultraschallelastographiebildern zu klären. Gleichzeitig wird die Entwicklung von neuartigen Datenerfassung- und Analysetechniken für fortgeschrittene Bildgebungsanwendungen vorangetrieben werden.

Wissenschaftlicher und gesellschaftlicher Kontext des Forschungsprojekts

Verschiedene bildgebende Verfahren und Modalitäten, wie z.B. die Gewebeelastizität, liefern Ärzten zusätzliche Informationen die eine bessere Diagnose und Vorsorge ermöglichen.  Die Ergebnisse unserer Forschung werden die aktuellen klinischen Methoden verbessern, indem die Gewebeelastizitätsermittlung in das Arsenal der täglichen Medizin gebracht wird.

Direct link to Lay Summary Last update: 15.07.2014

Lay Summary (English)

Lead
Tissue elasticity has been used in medicine as an indication of tissue anomalies for centuries. Palpation of breast and prostate are still the most common clinical procedures in cancer screening for those corresponding anatomical structures. Elastography is an emerging technique for imaging tissue viscoelasticity. This project aims to address some of the pending issues in generating ultrasound elastography images, while also investigating novel acquisition and analysis techniques for advanced imaging applications.
Lay summary
Aims of the research project

Elastography is an emerging technique for imaging tissue viscoelasticity from internal tissue displacements observed often in magnetic resonance or ultrasound time sequences.  Elastography based on ultrasound is particularly important, as ultrasound is real-time, cost-effective, non-ionizing, and thus a widely-used imaging modality.  Elastography has great potential in diagnosis and treatment planning because pathologies, e.g. tumors and cirrhosis, are often stiffer than their surrounding tissue.  It can furthermore be beneficial as an indication of tissue composition for robust characterization and segmentation of anatomical structures with different mechanical properties, e.g. for arterial plaque characterization.   Despite all these benefits, elastography is still not fully exploited in clinics.  Several different methodological approaches proposed in this field are still not fully mature and there is a clear need for robust methods for imaging tissue elasticity in an accurate, fast, and reproducible way.  This project aims to address some of the pending issues in generating ultrasound elastography images, while also investigating novel acquisition and analysis techniques for advanced imaging applications.

Scientific and societal context of the research project

Different imaging techniques and modalities provide additional information to physicians for better diagnosis and screening, and tissue elasticity is one such information that clinicians can exploit in their decision making. Results of our research will improve current clinical practices by helping to bring tissue elasticity imaging into the arsenal of everyday medicine.
Direct link to Lay Summary Last update: 15.07.2014

Responsible applicant and co-applicants

Employees

Publications

Publication
Simulation and Synthesis in Medical Imaging
Ninon Burgos, Gooya Ali, Oguz Ipek, Goksel Orcun (ed.) (2018), Simulation and Synthesis in Medical Imaging, Springer, Granada.
Breast-Density Assessment with Handheld Ultrasound: A Novel Biomarker to Assess Breast Cancer Risk and to Tailor Screening?
Sanabria Sergio J, Goksel Orcun, Martini Katharina, Forte Serafino, Frauenfelder Thomas, Kubik-Huch Rahel A, Rominger Marga B (2018), Breast-Density Assessment with Handheld Ultrasound: A Novel Biomarker to Assess Breast Cancer Risk and to Tailor Screening?, in European Radiology, 28(8), 3165-3175.
FEM Based Elasticity Reconstruction Using Ultrasound For Imaging Tissue Ablation
Otesteanu Corin F, Vishnevskiy Valeriy, Goksel Orcun (2018), FEM Based Elasticity Reconstruction Using Ultrasound For Imaging Tissue Ablation, in Int J Computer Assisted Radiology and Surgery, 13(6), 885-894.
A musculoskeletal model of the shoulder combining multibody dynamics and FEM using B-Spline elements
Pean Fabien, Fuernstahl Philipp, Goksel Orcun (2018), A musculoskeletal model of the shoulder combining multibody dynamics and FEM using B-Spline elements, in Int Symp Computer Methods in Biomechanics and Biomedical Engineering (CMBBE), Lisbon, PortugalCMBBE, Portugal.
Image-based Reconstruction of Tissue Scatterers using Beam Steering for Ultrasound Simulation
Mattausch Oliver, Goksel Orcun (2018), Image-based Reconstruction of Tissue Scatterers using Beam Steering for Ultrasound Simulation, in IEEE Trans Medical Imaging, 37(3), 767-780.
Breast cancer assessment with hand-held ultrasound based Speed of Sound: preliminary results
Sanabria Sergio, Martini Katharina, Rominger Marga, Dedes Konstantin, Vorburger D., Frauenfelder Thomas, Goksel Orcun (2018), Breast cancer assessment with hand-held ultrasound based Speed of Sound: preliminary results, in European Conference on Radiology (ECR), Vienna, AustriaEuropean Conference on Radiology, Austria.
Hand-held speed-of-sound ultrasound -- a novel cost-efficient biomarker for breast density assessment
Martini Katharina, Sanabria Sergio J, Forte Serafino, Kubik-Huch Rahel A, Frauenfelder Thomas, Goksel Orcun, Rominger Marga B. (2018), Hand-held speed-of-sound ultrasound -- a novel cost-efficient biomarker for breast density assessment, in European Conference on Radiology (ECR), Vienna, AustriaEuropean Conference on Radiology, Austria.
Realistic Ultrasound Simulation of Complex Surface Models Using Interactive Monte-Carlo Path Tracing
Mattausch Oliver, Makhinya Maxim, Goksel Orcun (2018), Realistic Ultrasound Simulation of Complex Surface Models Using Interactive Monte-Carlo Path Tracing, in Computer Graphics Forum, 37(1), 202-213.
Compliance Boundary Conditions for Patient-Specific Deformation Simulation Using the Finite Element Method
Ozkan Ece, Goksel Orcun (2018), Compliance Boundary Conditions for Patient-Specific Deformation Simulation Using the Finite Element Method, in Biomedical Physics & Engineering Express, 4(2), 025003-025003.
Inverse Problem of Ultrasound Beamforming with Sparsity Constraints and Regularization
Ozkan Ece, Vishnevsky Valeriy, Goksel Orcun (2018), Inverse Problem of Ultrasound Beamforming with Sparsity Constraints and Regularization, in IEEE Trans Ultrasonics, Ferroelectrics, and Frequency Control, 65(3), 356-365.
Can speed of sound be better than conventional elastography for breast characterization?
Sanabria Sergio J, Rominger Marga B, Otesteanu Corin F, Sheikh Farrukh I, Klingmueller Volker, Goksel Orcun (2017), Can speed of sound be better than conventional elastography for breast characterization?, in Annual Meeting of Radiological Society of North America (RSNA), Chicago, IL, USARadiological Society of North America, Chicago.
Quantification of nonlinear elastic constants using polynomials in quasi-incompressible soft solids
Otesteanu Corin F., Chintada Bhaskara R., Mazza Edoardo, Sanabria Sergio J., Goksel Orcun (2017), Quantification of nonlinear elastic constants using polynomials in quasi-incompressible soft solids, in IEEE Int Ultrasonics Symp (IUS), Washington, DC, USAIEEE, --.
Reflector-Based 3D Tomographic Ultrasound Reconstruction: Simulation Study
Chintada Bhaskara R., Sanabria Sergio J., Bost Wolfgang, Goksel Orcun (2017), Reflector-Based 3D Tomographic Ultrasound Reconstruction: Simulation Study, in IEEE Int Ultrasonics Symp (IUS), Washington, DC, USAIEEE, --.
Consistent Reconstruction of 4D Fetal Heart Ultrasound Images to Cope with Fetal Motion
Tanner Christine, Flach Barbara, Eggenberger Céline, Mattausch Oliver, Bajka Michael, Goksel Orcun (2017), Consistent Reconstruction of 4D Fetal Heart Ultrasound Images to Cope with Fetal Motion, in Int J Computer Assisted Radiology and Surgery, 12(8), 1307-1317.
Robust Motion Tracking in Liver from 2D Ultrasound Images Using Supporters
Ozkan Ece, Tanner Christine, Kastelic Matej, Mattausch Oliver, Makhinya Maxim, Goksel Orcun (2017), Robust Motion Tracking in Liver from 2D Ultrasound Images Using Supporters, in Int J Computer Assisted Radiology and Surgery, 12(6), 941-950.
Abdominal Motion Tracking and Prediction in 2D Ultrasound
Goksel Orcun, DeLuca Valeria, Makhinya Maxim, Tanner Christine (2016), Abdominal Motion Tracking and Prediction in 2D Ultrasound, in 4D Treatment Planning (4DTP) Workshop, Groningen, NetherlandsN/A, N/A.
4D Reconstruction of Fetal Heart Ultrasound Images in Presence of Fetal Motion
Christine Tanner, Celine Eggenberger, Barbara Flach, Oliver Mattausch, Michael Bajka, Orcun Goksel (2016), 4D Reconstruction of Fetal Heart Ultrasound Images in Presence of Fetal Motion, in Medical Image Computing and Computer Assisted Intervention (MICCAI), Athens, GreeceSpringer, Heidelberg.
Compliance Boundary Conditions for Elasticity Reconstruction Using FEM Inverse Problem
Ece Ozkan, Orcun Goksel (2016), Compliance Boundary Conditions for Elasticity Reconstruction Using FEM Inverse Problem, in International Tissue Elasticity Conference, Vermont, NE, USAN/A, N/A.
Graphical Modeling of Ultrasound Propagation in Tissue for Automatic Bone Segmentation
Firat Ozdemir, Ece Ozkan, Orcun Goksel (2016), Graphical Modeling of Ultrasound Propagation in Tissue for Automatic Bone Segmentation, in Medical Image Computing and Computer Assisted Intervention (MICCAI), Athens, GreeceSpringer, Heidelberg.
Hand-held Sound-Speed Mammography Based on Ultrasound Reflector Tracking
Sergio J. Sanabria, Orcun Goksel (2016), Hand-held Sound-Speed Mammography Based on Ultrasound Reflector Tracking, in Medical Image Computing and Computer Assisted Intervention (MICCAI), Athens, GreeceSpringer, Heidelberg.
Image-based PSF Estimation for Ultrasound Training Simulation
Mattausch Oliver, Goksel Orcun (2016), Image-based PSF Estimation for Ultrasound Training Simulation, in MICCAI W Simulation and Synthesis in Medical Imaging ({SASHIMI}), Athens, Greece23-33, Springer, Cham23-33.
Low Cost Alternative for Ultrasound Harmonic Elastography
Corin F. Otesteanu, Sergio J. Sanabria, Orcun Goksel (2016), Low Cost Alternative for Ultrasound Harmonic Elastography, in International Tissue Elasticity Conference, Vermont, NE, USAN/A, N/A.
Mobile Ultrasound Imaging on Heterogeneous Multi-Core Platform
Andreas Kurth, Andreas Tretter, Pascal A. Hager, Sergio Sanabria, Orcun Goksel, Lothar Thiele, Luca Benini (2016), Mobile Ultrasound Imaging on Heterogeneous Multi-Core Platform, in ACM/IEEE Symp on Embedded Systems for Real-time Multimedia (ESTIMedia), Pittsburgh, USAIEEE, IEEE.
Non-Linear Characterization of the Liver by Combining Shear and Longitudinal Wave Speed With Strain Observations
Sergio J Sanabria, Marga Rominger, Corin F. Otesteanu, Edoardo Mazza, Orcun Goksel (2016), Non-Linear Characterization of the Liver by Combining Shear and Longitudinal Wave Speed With Strain Observations, in International Tissue Elasticity Conference, Vermont, NE, USAN/A, N/A.
PURE: Panoramic Ultrasound Reconstruction by Seamless Stitching of Volumes
Barbara Flach, Maxim Makhinya, Orcun Goksel (2016), PURE: Panoramic Ultrasound Reconstruction by Seamless Stitching of Volumes, in MICCAI Workshop on Simulation and Synthesis in Medical Imaging, Athens, GreeceSpringer, Heidelberg.
Inverse Problem of Ultrasound Beamforming Using Sparsifying Bases
Ece Ozkan, Orcun Goksel (2016), Inverse Problem of Ultrasound Beamforming Using Sparsifying Bases, in IEEE Int Ultrasonics Symposium (IUS), Tours, FranceIEEE, IEEE.
Monte-Carlo Ray-Tracing for Realistic Interactive Ultrasound Simulation
Mattausch Oliver, Goksel Orcun (2016), Monte-Carlo Ray-Tracing for Realistic Interactive Ultrasound Simulation, in Eurographics W Visual Computing for Biology and Medicine ({VCBM}), Bergen, Norway1-9, The Eurographics Association, --1-9.
Analysis of Excitation Frequency in Elasticity Reconstruction Using the FEM Inverse-Problem
Corin Felix Otesteanu, Sergio J Sanabria, Orcun Goksel (2016), Analysis of Excitation Frequency in Elasticity Reconstruction Using the FEM Inverse-Problem, in IEEE International Symposium on Biomedical Imaging (ISBI), Prague, Czech RepublicIEEE, IEEE.
Compliance Boundary Conditions for Simulating Deformations in a Limited Region of Interest
Ozkan Ece, Goksel Orcun (2015), Compliance Boundary Conditions for Simulating Deformations in a Limited Region of Interest, in IEEE Engineering in Medicine and Biology Conference, Milano, ItalyIEEE, IEEE.
Hand-held Sound-speed Imaging for the Reconstruction of Bulk Modulus and Poisson Ratio in a Commercial Tissue-Mimicking Phantom
Sanabria Sergio J, Otesteanu Corin F, Goksel Orcun (2015), Hand-held Sound-speed Imaging for the Reconstruction of Bulk Modulus and Poisson Ratio in a Commercial Tissue-Mimicking Phantom, in International Tissue Elasticity Conference, Verona, ItalyN/A, N/A.
Thermal expansion imaging for monitoring lesion depth using M-mode ultrasound during cardiac RF ablation: in vitro study
Baki Peter, Sanabria Sergio J., Kosa Gabor, Szekely Gabor, Goksel Orcun (2015), Thermal expansion imaging for monitoring lesion depth using M-mode ultrasound during cardiac RF ablation: in vitro study, in International Journal of Computer Assisted Radiology and Surgery, 10(6), 681-693.
Total-Variation Regularization of Hand-held Limited-Angle Sound-Speed Tomography Based on Coherent Reflector for Breast Cancer Detection
Sanabria Sergio J, Goksel Orcun (2015), Total-Variation Regularization of Hand-held Limited-Angle Sound-Speed Tomography Based on Coherent Reflector for Breast Cancer Detection, in International Tissue Elasticity Conference, Verona, ItalyN/A, N/A.

Collaboration

Group / person Country
Types of collaboration
Prof. Edoardo Mazza, Institute of Mechanical Systems, D-MAVT, ETH Zurich Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure
Prof. Luca Benini, Integrated Systems Laboratory, D-ITET, ETH Zurich Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure
Prof. Jürg Hodler, Dept of Diagnostic and Interventional Radiology, Unispital Zürich Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
International Conference on Information Processing in Computer-Assisted Interventions Talk given at a conference FEM Based Elasticity Reconstruction Using Ultrasound For Imaging Tissue Ablation 20.06.2018 Berlin, Germany Vishnevskiy Valery; Otesteanu Corin Felix; Goksel Orcun;
European Conference on Radiology Poster Breast cancer assessment with hand-held ultrasound based Speed of Sound: preliminary results 28.02.2018 Vienna, Austria Sanabria Martin Sergio José;
Annual Meeting of Radiological Society of North America (RSNA) Talk given at a conference Can speed of sound be better than conventional elastography for breast characterization? 01.11.2017 Chicago, IL, United States of America Sanabria Martin Sergio José;
IEEE International Ultrasonics Symposium (IUS) 2017 Poster Quantification of nonlinear elastic constants using polynomials in quasi-incompressible soft solids 05.09.2017 Washington, DC, United States of America Otesteanu Corin Felix; Goksel Orcun;
IEEE International Ultrasonics Symposium (IUS) 2017 Poster Reflector-based 3d tomographic ultrasound reconstruction: Simulation study 05.09.2017 Washington, DC, United States of America Goksel Orcun;
EXCITE Zurich Summer School 2017 Talk given at a conference Lecture: Ultrasound and Optoacoustic Imaging 04.09.2017 Zurich, Switzerland Özkan Ece; Goksel Orcun;
IEEE Int Ultrasonics Symp (IUS) Poster Quantification of nonlinear elastic constants using polynomials in quasi-incompressible soft solids 01.09.2017 Washington, DC, United States of America Otesteanu Corin Felix; Chintada Bhaskara Rao;
IEEE Int Ultrasonics Symp (IUS) Poster Reflector-Based 3D Tomographic Ultrasound Reconstruction: Simulation Study 01.09.2017 Washington, DC, United States of America Chintada Bhaskara Rao;
Information Processing in Computer-Assisted Interventions (IPCAI) Conference 2017 Talk given at a conference Robust Motion Tracking in Liver from 2D Ultrasound Images Using Supporters 20.06.2017 Barcelona, Spain Özkan Ece; Goksel Orcun;
Fraunhofer Institute, MEVIS Lab Individual talk Ultrasound imaging and biomechanical tissue characterization 27.05.2017 Bremen, Germany Goksel Orcun;
University of British Columbia, Dept of Electrical and Computer Eng Individual talk Computer-assisted Applications in Medicine 09.01.2017 Vancouver, BC, Canada Goksel Orcun;
4D Treatment Planning (4DTP) Workshop 2016 Poster Abdominal motion tracking and prediction in 2d ultrasound 01.11.2016 Groningen, Netherlands Goksel Orcun;
Medical Image Analysis and Computer Assisted Intervention (MICCAI) Conf 2016 Talk given at a conference Hand-held sound-speed mammography based on ultrasound reflector tracking 17.10.2016 Athens, Greece Goksel Orcun; Sanabria Martin Sergio José;
Medical Image Analysis and Computer Assisted Intervention (MICCAI) Conf 2016 Poster 4D reconstruction of fetal heart ultrasound images in presence of fetal motion 17.10.2016 Athens, Greece Goksel Orcun;
MICCAI SASHIMI Workshop 2016 Talk given at a conference Image-based PSF estimation for ultrasound training simulation 17.10.2016 Athens, Greece Goksel Orcun;
Medical Image Analysis and Computer Assisted Intervention (MICCAI) Conf 2016 Poster Graphical modeling of ultrasound propagation in tissue for automatic bone segmentation. 17.10.2016 Athens, Greece Goksel Orcun; Özkan Ece;
International Tissue Elasticity Conference (ITEC) 2016 Talk given at a conference Compliance boundary conditions for elasticity reconstruction using FEM inverse problem 16.10.2016 Lake Morey, Vermont, United States of America Özkan Ece;
International Tissue Elasticity Conference (ITEC) 2016 Talk given at a conference Low cost alternative for ultrasound harmonic elastography 16.10.2016 Lake Morey, Vermont, United States of America Otesteanu Corin Felix;
International Tissue Elasticity Conference (ITEC) 2016 Talk given at a conference Nonlinear characterization of the liver by combining shear and longitudinal wave speed with strain observations 16.10.2016 Lake Morey, Vermont, United States of America Goksel Orcun; Sanabria Martin Sergio José; Otesteanu Corin Felix;
IEEE International Ultrasonics Symposium (IUS) 2016 Poster Inverse Problem of Ultrasound Beamforming with Sparsity in Time and Frequency Domain 06.09.2016 Tours, France Goksel Orcun; Özkan Ece;
Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM) 2017 Talk given at a conference Monte-Carlo Ray-Tracing for Realistic Interactive Ultrasound Simulation 05.09.2016 Bergen, Norway Goksel Orcun;
EXCITE Zurich Summer School 2016 Talk given at a conference Medical ultrasound imaging workshop: lecture + hands-on 05.09.2016 Zurich, Switzerland Goksel Orcun; Sanabria Martin Sergio José; Otesteanu Corin Felix;
IEEE International Symposium on Biomedical Imaging (ISBI) 2016 Poster Analysis of Excitation Frequency in Elasticity Reconstruction Using the FEM Inverse-Problem 13.04.2016 Prague, Czech Republic Goksel Orcun; Otesteanu Corin Felix; Sanabria Martin Sergio José;
IEEE International Symposium on Biomedical Imaging (ISBI) 2016 Poster Imaging of Sliding Visceral Interfaces During Breathing 13.04.2016 Prague, Czech Republic Goksel Orcun;
4D Treatment Planning (4DTP) Workshop 2015 Poster Real-time Tracking of Liver Landmarks in 2D Ultrasound Sequences 26.11.2015 Dresden, Germany Goksel Orcun;
International Tissue Elasticity Conference (ITEC) 2015 Talk given at a conference Total-Variation Regularization of Hand-held Limited-Angle Sound-Speed Tomography Based on Coherent Reflector for Breast Cancer Detection 21.09.2015 Verona, Italy Goksel Orcun; Sanabria Martin Sergio José;
International Tissue Elasticity Conference (ITEC) 2015 Talk given at a conference Hand-held Sound-speed Imaging for the Reconstruction of Bulk Modulus and Poisson Ratio in a Commercial Tissue-Mimicking Phantom 21.09.2015 Verona, Italy Otesteanu Corin Felix; Sanabria Martin Sergio José; Goksel Orcun;
EXCITE Zurich Summer School 2015 Talk given at a conference Medical ultrasound imaging workshop: lecture + hands-on 31.08.2015 Zurich, Switzerland Sanabria Martin Sergio José; Goksel Orcun; Otesteanu Corin Felix;
IEEE Engineering in Medicine and Biology Conference (EMBC) 2015 Poster Compliance Boundary Conditions for Simulating Deformations in a Limited Region of Interest 25.08.2015 Milan, Italy Goksel Orcun; Özkan Ece;
Information Processing in Computer-Assisted Interventions (IPCAI) Conference 2015 Talk given at a conference Thermal expansion imaging for monitoring lesion depth using M-mode ultrasound during cardiac RF ablation: in vitro study 24.06.2015 Barcelona, Spain Goksel Orcun; Sanabria Martin Sergio José;
IEEE International Symposium on Biomedical Imaging 2015 Talk given at a conference Unsupervised Detection of Local Errors in Image Registration 16.05.2015 New York, NY, United States of America Goksel Orcun;
4D Treatment Planning (4DTP) Workshop 2014 Poster Total Variation Regularization of Displacements in Parametric Image Registration 28.11.2014 London, UK (UK is not in the country list above!), British Virgin Islands Goksel Orcun;


Self-organised

Title Date Place

Knowledge transfer events

Active participation

Title Type of contribution Date Place Persons involved
Swiss Venture Kick-off event Talk 31.01.2018 Zurich, Switzerland Goksel Orcun;


Communication with the public

Communication Title Media Place Year
Media relations: print media, online media CARS Daily News: Ece Ozkan "Best Paper Runnerup at IPCAI" and interview Online Magazine: "Computer-Vision News" International 2017
Media relations: radio, television Reflector-based ultrasound ReflectUS winning 2017 Swiss Venture Best Idea Award SRF, RTS, Netzwoche,ETH Foundation, Echo der Zeit, ... German-speaking Switzerland Western Switzerland 2017
Talks/events/exhibitions Scientifica (ETH public outreach event) German-speaking Switzerland 2017
Media relations: print media, online media "Best of MICCAI" for Sanabria&Goksel paper oral presentation Online Magazine: "Computer-Vision News" International 2016
Media relations: print media, online media "Brustkrebs erkennen" local newspapers (e.g. "der Landbote") German-speaking Switzerland 2016
Media relations: print media, online media ETH Zurich Spark Award 2016: Hand-held Ultrasound Imaging of Speed-of-Sound for Breast Examination ETH webpage + magazine German-speaking Switzerland 2016
Media relations: radio, television Spark Award on breast-cancer detection SRF German-speaking Switzerland 2016
Talks/events/exhibitions Einführungsforlesung @ ETH Zürich German-speaking Switzerland International 2015

Awards

Title Year
NDI Young Investigator Travel Award 2018
Information Processing in Computer-assisted Interventions (IPCAI) PHILIPS Best Paper Runnerup, Barcelona, Spain, Jun 2017
MICCAI IJCARS Best Paper Runnerup, Sep 2017
Swiss MedTech Science Slam Finalist, Jun 2017
Swiss Venture Best Idea Award, Jun 2017
Best Paper Award, at Eurographics VCBM, Bergen, Norway, Sep 2016
ETH Zurich Spark Award for the best invention of the year 2016
3rd place in Best Paper Award (of 100 submissions) at Information Processing in Computer-Assisted Interventions (IPCAI) Conference Barcelona, Spain, Jun 2015
Best Poster Award at 4D Treatment Planning Workshop, Dresden, Germany, Nov 2015
Best Poster Award at 4D Treatment Planning Workshop London, UK, Nov 2014

Associated projects

Number Title Start Funding scheme
179116 Imaging Soft Tissue Elasticity 01.08.2018 SNSF Professorships
179116 Imaging Soft Tissue Elasticity 01.08.2018 SNSF Professorships

Abstract

Elastography is an emerging technique for imaging tissue viscoelasticity from observed tissue displacements, often tracked in magnetic resonance or ultrasound time sequences. Elastography based on ultrasound is particularly important, as ultrasound is real-time, cost-effective, non-ionizing, and thus a widely-used imaging modality. Elastography has great potential in diagnosis and treatment planning because pathologies, e.g. tumors and cirrhosis, are often stiffer than their surrounding tissue. Elasticity is furthermore an indication of tissue composition, as used in characterization of arterial plaques, and hence may facilitate robust segmentation of anatomical structures that have different mechanical properties. Despite all such benefits, this technology is still not fully exploited in clinics. Several different methodological approaches in this field are still not fully mature, and thus very few of those been commercialized and clinically utilized. Accordingly, there is substantial need for robust methods for imaging tissue elasticity in an accurate, fast, and repeatable way. This proposed project aims to address some of the current issues in elastography, in particular regarding the methods based on finite element (FE) inverse problem (IP) formulations, by investigating novel acquisition and analysis techniques.
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