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Transportation noise, annoyance, sleep and cardiometabolic risk: an integrated approach on short- and long-term effects

English title Transportation noise, annoyance, sleep and cardiometabolic risk: an integrated approach on short- and long-term effects
Applicant Röösli Martin
Number 147635
Funding scheme Sinergia
Research institution Swiss Tropical and Public Health Institute Medical Services and Diagnostic Universität Basel
Institution of higher education University of Basel - BS
Main discipline Methods of Epidemiology and Preventive Medicine
Start/End 01.01.2014 - 31.12.2017
Approved amount 1'500'000.00
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All Disciplines (2)

Discipline
Methods of Epidemiology and Preventive Medicine
Environmental Research

Keywords (12)

noise annoyance; human experiment; aircraft noise; epidemiology; sleep; transportation noise; cardiovascular diseases; railway noise; noise modeling; road traffic noise; metabolic syndrome; acoustics

Lay Summary (German)

Lead
Das Hauptziel dieser interdisziplinären Studie ist die Untersuchung von akuten, kurz- und langfristigen Auswirkungen von Strassen-, Schienen- und Flugverkehrslärm auf die Belästigung, den Schlaf und die kardiometabolische Gesundheit. Dabei wird im Schlaflabor, mittels Befragungen und in epidemiologischen Studien vertieft evaluiert, welche Rolle dabei die Lärmcharakteristika und Persönlichkeitsmerkmale wie Lärmsensitivität oder genetische Prädisposition spielen.
Lay summary

Ziele: Das Hauptziel der Studie ist die Untersuchung von akuten, kurz- und langfristigen Auswirkungen von Strassen-, Schienen- und Flugverkehrslärm auf die Belästigung, den Schlaf und die kardiometabolische Gesundheit. Insbesondere wird evaluiert welche Lärmcharakteristika für Schlafstörungen und langfristige gesundheitliche Auswirkungen bedeutsam sind. Weiter wird auch erforscht, welche Rollen die Lärmsensitivität, genetische Prädispositionen und andere Persönlichkeitsmerkmale spielen.

Methode: Die Lärmbelastung durch Strassen-, Schienen und Luftverkehr wird für die gesamte Schweizer Bevölkerung modelliert. Neben der Höhe der Belastung werden dabei auch andere Charakteristika berücksichtigt wie die tageszeitliche Verteilung oder die Ereignishaftigkeit der Lärmbelastung. Im Schlaflabor werden Probanden während einer Woche zufällig verschiedenen Lärmszenarien ausgesetzt und Effekte auf den Schlaf, kardiometabolische Parameter und kognitive Leistungsfähigkeit am Folgetag analysiert. In einer repräsentativen Bevölkerungserhebung wird evaluiert, wie stark die Verkehrslärmbelästigung im Alltag ist und wie damit umgegangen wird. In zwei grossen laufenden epidemiologischen Studien (SAPALDIA Biobank und Schweizer Nationale Kohortenstudie) wird unter Berücksichtigung von Biomarkern und anderen Faktoren wie Luftbelastung untersucht wie sich die Lärmbelastung zu Hause langfristig auf die kardiometabolische Gesundheit auswirkt.

Signifikanz: Eine besondere Stärke dieser interdisziplinären Studie ist die Kombination von experimentellen und epidemiologischen Forschungsmethoden, zur Erforschung der Wechselwirkungen von akuten, kurz- und langfristigen Auswirkungen. Für Strassen-, Schienen- und Luftverkehrslärm werden Expositions-Wirkungsbeziehungen hergeleitet und dabei verschiedene Charakteristika des Lärms mitberücksichtig. Damit kann das Gesundheitsrisiko der Lärmbelastung besser verstanden werden, was für eine adäquate Regulierung der Lärmbelastung relevant ist.

Direct link to Lay Summary Last update: 11.11.2013

Lay Summary (English)

Lead
The overall goal of this interdisciplinary study is to investigate acute, short- and long-term effects of road, railway and aircraft noise exposure on annoyance, sleep disturbances and cardiometabolic risk. Noise exposure patterns that most strongly affect individuals are identified by means of sleep experiments, surveys and epidemiological research. In addition, the role of individual characteristics such as age and gender, noise sensitivity and genetic predispositions will be elucidated.
Lay summary

Aims: The overall goal of this project is to investigate acute, short- and long-term effects of road, railway and aircraft noise exposure on annoyance, sleep disturbances and cardiometabolic risk. The project aims at identifying noise exposure patterns that most strongly affect individuals during sleep and thus may ultimately result in long-term health consequences.

Methods: A nationwide assessment of road, railway and aircraft noise exposure will be conducted. In addition to average exposure, exposure modelling will be considerably refined to reflect additional exposure characteristics such as the degree of intermittence of noise events or the diurnal distribution of noise. During a one-week period in the sleep-laboratory, volunteers will be randomly exposed to different noise scenarios and effects on sleep as well as cardiometabolic parameters and subsequent cognitive performance will be investigated. Noise annoyance and coping responses in the Swiss population will be evaluated via a representative survey. Taking into account biomarkers and other factors including air pollution, data from two large on-going epidemiological studies (SAPALDIA Biobank and Swiss National Cohort) will be used to explore the exposure-response association for the various traffic noise sources and cardiometabolic morbidity and mortality.

Significance: A key asset of this interdisciplinary study is the mutual combination of human experimental and epidemiological research to address acute, short- and long-term noise effects on sleep and cardiometabolic outcomes. Source-specific exposure-response functions will be determined giving due consideration to the acoustical characteristics of noise, such as the distribution of noise events during the night. This contribution to the understanding of health risks, especially for urban dwellers, and is highly relevant for regulating environmental noise.

Direct link to Lay Summary Last update: 11.11.2013

Responsible applicant and co-applicants

Employees

Publications

Publication
Differences between Outdoor and Indoor Sound Levels for Open, Tilted, and Closed Windows.
Locher Barbara, Piquerez André, Habermacher Manuel, Ragettli Martina, Röösli Martin, Brink Mark, Cajochen Christian, Vienneau Danielle, Foraster Maria, Müller Uwe, Wunderli Jean Marc (2018), Differences between Outdoor and Indoor Sound Levels for Open, Tilted, and Closed Windows., in International journal of environmental research and public health, 15(1), 149.
Exposure to Night-Time Traffic Noise, Melatonin-Regulating Gene Variants and Change in Glycemia in Adults.
Eze Ikenna C, Imboden Medea, Foraster Maria, Schaffner Emmanuel, Kumar Ashish, Vienneau Danielle, Héritier Harris, Rudzik Franziska, Thiesse Laurie, Pieren Reto, von Eckardstein Arnold, Schindler Christian, Brink Mark, Wunderli Jean-Marc, Cajochen Christian, Röösli Martin, Probst-Hensch Nicole (2017), Exposure to Night-Time Traffic Noise, Melatonin-Regulating Gene Variants and Change in Glycemia in Adults., in International journal of environmental research and public health, 14(12), 1492.
More than clean air and tranquillity: Residential green is independently associated with decreasing mortality.
Vienneau Danielle, de Hoogh Kees, Faeh David, Kaufmann Marco, Wunderli Jean Marc, Röösli Martin, Röösli Martin (2017), More than clean air and tranquillity: Residential green is independently associated with decreasing mortality., in Environment international, 108, 176-184.
Land Use Regression Modeling of Outdoor Noise Exposure in Informal Settlements in Western Cape, South Africa.
Sieber Chloé, Ragettli Martina S, Brink Mark, Toyib Olaniyan, Baatjies Roslyn, Saucy Apolline, Probst-Hensch Nicole, Dalvie Mohamed Aqiel, Röösli Martin (2017), Land Use Regression Modeling of Outdoor Noise Exposure in Informal Settlements in Western Cape, South Africa., in International journal of environmental research and public health, 14(10), 1262.
Exposure to Road, Railway, and Aircraft Noise and Arterial Stiffness in the SAPALDIA Study: Annual Average Noise Levels and Temporal Noise Characteristics.
Foraster Maria, Eze Ikenna C, Schaffner Emmanuel, Vienneau Danielle, Héritier Harris, Endes Simon, Rudzik Franziska, Thiesse Laurie, Pieren Reto, Schindler Christian, Schmidt-Trucksäss Arno, Brink Mark, Cajochen Christian, Marc Wunderli Jean, Röösli Martin, Probst-Hensch Nicole (2017), Exposure to Road, Railway, and Aircraft Noise and Arterial Stiffness in the SAPALDIA Study: Annual Average Noise Levels and Temporal Noise Characteristics., in Environmental health perspectives, 125(9), 097004-097004.
Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study
Eze I.C., Foraster M., Schaffner E., Vienneau D., Héritier H., Rudzik F., Thiesse L., Pieren R, Imboden M., von Eckardstein A., Schindler C., Brink M., Cajochen C., Wunderli J.M., Röösli M., Probst-Hensch N. (2017), Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study, in International Journal of Epidemiology, 46(4), 1115-1125.
Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland.
Héritier H., Vienneau D., Foraster M., Eze I.C., Schaffner E., Thiesse L., Rudzik F., Habermacher M., Köpfli M., Pieren R., Brink M., Cajochen C., Wunderli J.M., Probst-Hensch N., Röösli M. for the SNC study group (2017), Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland., in European Journal of Epidemiology, 32, 307-315.
Validation of large scale noise exposure modeling by long-term measurements
Felix Schlatter, André Piquerez, Manuel Habermacher, Martina S. Ragettli, Martin Röösli, Mark Brink, Christian Cajochen, Nicole Probst-Hensch, Maria Foraster, Jean Marc Wunderli (2017), Validation of large scale noise exposure modeling by long-term measurements, in Noise Mapping, 4, 75-86.
Effects of Scale, Question Location, Order of Response Alternatives, and Season on Self-Reported Noise Annoyance Using ICBEN Scales: A Field Experiment.
Brink Mark, Schreckenberg Dirk, Vienneau Danielle, Cajochen Christian, Wunderli Jean-Marc, Probst-Hensch Nicole, Röösli Martin (2016), Effects of Scale, Question Location, Order of Response Alternatives, and Season on Self-Reported Noise Annoyance Using ICBEN Scales: A Field Experiment., in International journal of environmental research and public health, 13(11), 1-19.
Intermittency ratio: A metric reflecting short-term temporal variations of transportation noise exposure
Wunderli Jean Marc, Pieren Reto, Habermacher Manuel, Vienneau Danielle, Cajochen Christian, Probst-Hensch Nicole, Röösli Martin, Brink Mark (2016), Intermittency ratio: A metric reflecting short-term temporal variations of transportation noise exposure, in Journal of Exposure Science and Environmental Epidemiology, 26, 575-585.
Long-term transportation noise annoyance is associated with subsequent lower levels of physical activity.
Foraster Maria, Eze Ikenna C, Vienneau Danielle, Brink Mark, Cajochen Christian, Caviezel Seraina, Héritier Harris, Schaffner Emmanuel, Schindler Christian, Wanner Miriam, Wunderli Jean-Marc, Röösli Martin, Probst-Hensch Nicole (2016), Long-term transportation noise annoyance is associated with subsequent lower levels of physical activity., in Environment international, 91, 341-9.
The relationship between transportation noise exposure and ischemic heart disease: A meta-analysis
Vienneau Danielle, Schindler Christian, Perez Laura, Probst-Hensch Nicole, Röösli Martin (2015), The relationship between transportation noise exposure and ischemic heart disease: A meta-analysis, in Environmental Research, 138, 372-380.
Reconstruction of historical noise exposure data for environmental epidemiology in Switzerland within the SiRENE project
Karipidis Ioannis, Vienneau Danielle, Habermacher Manuel, Köpfli Mischa, Brink Mark, Probst-Hensch Nicole, Röösli Martin, Wunderlin Jean-Marc (2014), Reconstruction of historical noise exposure data for environmental epidemiology in Switzerland within the SiRENE project, in Noise Mapping, 1, 3-14.
SiRENE - an interdisciplinary study on the health effects of transportation noise exposure: noise calculation solutions on the example of air traffic
Karipidis Ioannis, Köpfli Mischa, Vienneau Danielle, Brink Mark, Cajochen Christian, Probst-Hensch Nicole, Röösli Martin, Schäffer Beat, Wunderli Jean-Marc (2014), SiRENE - an interdisciplinary study on the health effects of transportation noise exposure: noise calculation solutions on the example of air traffic.
The association between road traffic noise exposure, annoyance and health-related quality of life (HRQOL)
Héritier Harris, Vienneau Danielle, Frei Patricia, Eze Ikenna, Brink Mark, Probst-Hensch Nicole, Röösli Martin (2014), The association between road traffic noise exposure, annoyance and health-related quality of life (HRQOL), in International Journal of Environmental Research and Public Health, 11, 12652-12667.
Years of life lost and morbidity cases attributable to transportation noise and air pollution: A comparative health risk assessment for Switzerland in 2010
Vienneau Danielle, Perez Laura, Schindler Christian, Lieb Christoph, Sommer Heini, Probst-Hensch Nicole, Künzli Nino, Röösli Martin (2014), Years of life lost and morbidity cases attributable to transportation noise and air pollution: A comparative health risk assessment for Switzerland in 2010, in International Journal of Hygiene and Environmental Health, 218(6), 514-521.
Diurnal variability of transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland
Héritier Harris, Danielle Vienneau, Maria Foraster, Ikenna C. Eze, Emanuel Schaffner, Laurie Thiesse, Fanziska Rudzik, Manuel Habermacher, Micha Kopfli, Reto Pieren, Arno Schmidt-Trucksäss, Mark Brink, Christian Cajochen, Jean Marc Wunderli, Nicole Probst-Hensch, Martin Röösli, Diurnal variability of transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland, in International Journal of Hygiene and Environmental Health.

Collaboration

Group / person Country
Types of collaboration
Université Libre, Brussels, Belgium (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Fachhochschule St. Gallen Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
SBB Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Research Infrastructure
Institut für Sozial- und Präventivmedizin, Bern Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Research Infrastructure
University of Lyon France (Europe)
- in-depth/constructive exchanges on approaches, methods or results
Colaus Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure
Maersk Mc-Kinney Moller Institute, Odense Denmark (Europe)
- Publication
- Exchange of personnel
Division des Maladies Chroniques, IUSMP, CHUV Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
International Society for Environmental Epidemiology Talk given at a conference Dirunal variation of transportation no Oral at ISEE Sydney, Australia, ise exposure and cardiovascular mortality in Switzerland 24.09.2017 Sidney, Australia Vienneau Danielle;
International Society for Environmental Epidemiology Poster Exposure, annoyance, and sensitivity to noise in informal settlements in the Western Cape province, South Africa 24.09.2017 Sidney, Australia Vienneau Danielle;
Jahrestagung der Schweizerischen Gesellschaft für Schlafforschung, Schlafmedizin und Chronobiologie (SGSSC) Talk given at a conference Deleterious effect of nocturnal transportation noise on sleep, glucose tolerance and insulin sensitivity 06.09.2017 Lugano, Switzerland Thiesse Laurie;
31st Annual Meeting of the Associated Professional Sleep Societies (APSS) Poster Spindle density and arousability from acoustic stimulation during sleep 03.06.2017 Boston, United States of America Rudzik Franziska;
31st Annual Meeting of the Associated Professional Sleep Societies (APSS) Poster Temporal variation of transportation noise during sleep impacts on glucose metabolism 03.06.2017 Boston, United States of America Thiesse Laurie;
European Sleep Research Society (ESRS) Talk given at a conference Short-term effect of nocturnal transportation noise on glucose metabolism. 13.09.2016 Bologna, Italy Thiesse Laurie;
ISEE Conference Poster Relationship between long-term residential noise characteristics and incident diabetes in the SAPALDIA study 01.09.2016 Rome, Italy Eze Ikenna;
ISEE Conference Talk given at a conference Source-specific transportation noise mortality from heart failure and myocardial infarction in Switzerland. 01.09.2016 Rome, Italy Vienneau Danielle;
INTER-NOISE 2016 Talk given at a conference Source-specific transportation noise mortality from heart failure and myocardial infarction in Switzerland. 21.08.2016 Hamburg, Germany Héritier Harris;
INTER-NOISE 2016 Talk given at a conference Parameter study on IR, a metric reflecting short-term temporal variations of transportation noise exposure 21.08.2016 Hamburg, Germany Wunderli Jean Marc;
INTER-NOISE 2016 Talk given at a conference Do short-term temporal variations of noise exposure explain variance of noise annoyance? 21.08.2016 Hamburg, Germany Wunderli Jean Marc;
INTER-NOISE 2016 Talk given at a conference Effects of continuous and intermittent transportation noise on sleep fragmentation. 21.08.2016 Hamburg, Germany Rudzik Franziska;
INTER-NOISE 2016 Talk given at a conference Short-term effect of nocturnal transportation noise on glucose metabolism. 21.08.2016 Hamburg, Germany Thiesse Laurie;
Society for Research on Biological Rhythms (SRBR). Tampa Poster Short-term effect of nocturnal transportation noise on glucose metabolism. 21.05.2016 Tampa, United States of America Thiesse Laurie;
Jahrestagung der Schweizerischen Gesellschaft für Schlafforschung, Schlafmedizin und Chronobiologie (SSSSC). Poster Short-term effect of nocturnal transportation noise on glucose metabolism. 28.04.2016 Basel, Switzerland Thiesse Laurie;
Jahrestagung der Schweizerischen Gesellschaft für Schlafforschung, Schlafmedizin und Chronobiologie (SSSSC). Poster Effects of continuous and intermittent transportation noise on sleep fragmentation. 28.04.2016 Basel, Switzerland Rudzik Franziska;
ISEE Young Researcher’s Conference 2015 Talk given at a conference Source-specific traffic noise exposure and cardiovascular mortality in Switzerland 02.11.2015 Utrecht, Netherlands Vienneau Danielle; Héritier Harris;
Swiss Public Health Conference 2015 Talk given at a conference Source-specific traffic noise exposure and cardiovascular mortality in Switzerland 17.09.2015 Geneva, Switzerland Röösli Martin; Héritier Harris;
ISEE conference: International Society for Environmental Epidemiology Poster Source-specific traffic noise exposure and cardiovascular mortality in Switzerland 31.08.2015 Sao Paolo, Brazil Vienneau Danielle;
Euronoise Conference 2015 Talk given at a conference Annoyance to transportation noise and risk of physical inactivity 31.05.2015 Maastricht, Netherlands Foraster Pulido Maria; Vienneau Danielle; Héritier Harris;
Euronoise Conference 2015 Talk given at a conference Source-specific traffic noise exposure and cardiovascular mortality in Switzerland 31.05.2015 Maastricht NL, Netherlands Héritier Harris; Foraster Pulido Maria; Wunderli Jean Marc; Vienneau Danielle;
ISEE Europe Young Researchers Conference Poster The association between road traffic noise exposure, annoyance and health-related quality of life (HRQOL 20.10.2014 Barcelona, Spain Vienneau Danielle; Röösli Martin; Héritier Harris;
ISEE Europe Young Researchers Conference Poster Association between long-term transportation noise annoyance and physical activity. 20.10.2014 Barcelona, Spain Probst-Hensch Nicole; Eze Ikenna;
ISEE Europe YR Conference Talk given at a conference Noise annoyance - exposure relationship as a validation criterion for evaluating exposure assessment quality 20.10.2014 Barcelona, Spain Vienneau Danielle;
22nd Congress of the European Sleep Research Society Poster Inter-individual differences in the effects of night-time noise exposure on sleep and cognitive performance during daytime 16.09.2014 Tallinn, Estonia Wunderli Jean Marc; Röösli Martin; Cajochen Christian;
ISEE Poster Exposure to road traffic noise, cardiometabolic risk and mental health: a prospective cohort study 24.08.2014 Seattle, United States of America Héritier Harris; Vienneau Danielle; Röösli Martin;
ISEE 2014 Talk given at a conference Years of life lost due to transportation noise and air pollution: a comparative risk assessment for Switzerland in 2010 24.08.2014 Seattle, United States of America Röösli Martin;
Swiss Public Health Conference Talk given at a conference Years of life lost due to transportation noise and air pollution: a comparative risk assessment for Switzerland in 2010 21.08.2014 Olten, Switzerland Vienneau Danielle;
Public Health Schweiz Poster The association between road traffic noise exposure, annoyance and health-related quality of life (HRQOL) 21.08.2014 Olten, Switzerland Röösli Martin; Vienneau Danielle; Héritier Harris;
Swiss Public Health Conference Individual talk Exposure to road traffic noise, cardiometabolic risk and mental health: a prospective cohort study 21.08.2014 Olten, Switzerland Vienneau Danielle;
Public Health Schweiz Poster SiRENE - an interdisciplinary study on the health effects of transportation noise exposure: a study protocol 21.08.2014 Olten, Switzerland Röösli Martin; Héritier Harris; Vienneau Danielle;
ICBEN Talk given at a conference Years of life lost due to transportation noise and air pollution: a comparative risk assessment for Switzerland in 2010 01.06.2014 Nara, Japan Vienneau Danielle;


Self-organised

Title Date Place
Symposium "The broadening noise phenome and its biological links" at ISEE Conference 2016, 01.09.2016 Rome, Italy

Knowledge transfer events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
Big Data, Small Area: An international symposium in celebration of 30 years of the Small Area Health Statistics Unit Talk 14.11.2017 London, Great Britain and Northern Ireland
Public Seminar Wissenschaftsforum in Kooperation mit Zukunft Rhein-Main (ZRM) Talk 11.07.2016 Frankfurt, Germany
Delegate Meeting Aefu (Ärztinnen und Ärzte für Umweltschutz), Basel. Talk 16.06.2016 Basel, Switzerland
3rd International Conference on Active Noise Abatement (ICANA) Talk 12.11.2015 Frankfurt, Germany
Quarterly meetings of the EKLB (Eidg. Kommission für Lärmbekämpfung) Talk 08.03.2015 Bern, Switzerland
Jährliche Sitzung des Schutzverbandes der Bevölkerung um den Flughafen Zürich Talk 19.11.2014 Oberglatt, Switzerland


Self-organised

Title Date Place
Herbsttagung SGA-SSA, Lärmwirkungen/Les effets du bruit Donnerstag 09.11.2017 Solothurn, Switzerland
Colloquim at Bafu: Update on the SiRENE study for the Division Noise and NIR in the Federal office for the environment (BAFU). 22.08.2015 Bern, Switzerland
Swiss TPH Monday Seminars 03.11.2014 Basel, Switzerland

Communication with the public

Communication Title Media Place Year
Media relations: print media, online media Die Gesundheit der Bevölkerung leidet unter dem Verkehrslärm BaZ German-speaking Switzerland 2017
Media relations: radio, television Lärm SRF1 10vor10 German-speaking Switzerland 2017
Talks/events/exhibitions Resultate der Lärmwirkungsstudie SiRENE, Gesundheitsrisiken durch Fluglärm, Informationsveranstaltun International 2017
Talks/events/exhibitions Workshop „SiRENE“, Tagung Tempo weg! Lärmliga, Bern German-speaking Switzerland Western Switzerland 2017
Talks/events/exhibitions Welcher Lärm ist besonders schädlich für das Herz-/Kreislaufsystem? Robert Müller Lecture, Mainz International 2016
Talks/events/exhibitions Viel Lärm um nichts German-speaking Switzerland 2015
Talks/events/exhibitions 50-jähriges Jubiläum EPMA Western Switzerland German-speaking Switzerland Italian-speaking Switzerland 2014
Talks/events/exhibitions 70-jähriges Jubiläum des Swiss TPH Western Switzerland Italian-speaking Switzerland German-speaking Switzerland 2014
Talks/events/exhibitions Gesundheitliche Auswirkungen von Fluglärm: neuste wissenschaftliche Erkenntnisse International 2014
Media relations: print media, online media Noise and Health Schweizer Illustrierte German-speaking Switzerland Italian-speaking Switzerland Western Switzerland 2014

Awards

Title Year
SSPH+ Award for the best published PhD article in Public Health, Harris Héritier et al. Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland, Europ J Epi, 2017, 32(4):307-315. 2017

Associated projects

Number Title Start Funding scheme
172026 Acute and short-term effects of night-time transportation noise exposure on sleep, cognition and cardio-metabolic measures 01.03.2017 Doc.Mobility
134273 The Swiss National Cohort: a platform for longitudinal research in Switzerland 01.07.2011 Cohort Studies Large
134276 Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA) 01.04.2011 Cohort Studies Large
173582 12th ICBEN Congress on Noise as a Public Health Problem 01.06.2017 Scientific Conferences
148470 SAPALDIA Cohort on Healthy Aging 01.04.2014 Cohort Studies Large
177506 SAPALDIA 5 - Cohort on Healthy Aging 01.04.2018 Cohort Studies Large
173330 Novel methods for investigating acute and long term effects of transportation noise on health 01.08.2017 Project funding (special)

Abstract

Background: Little is known about how acute and short-term noise effects, especially those that are observed during sleep, translate into long-term health consequences. In particular, it is unclear which acoustical characteristics of noise from different sources are most detrimental for human health and wellbeing.Aims: The overall goal of this project is to investigate the acute, short- and long-term effects of road, railway and aircraft noise exposure on annoyance and coping responses, sleep disturbances and cardiometabolic risk by mutually combining human experimental research in the laboratory with population-based epidemiological methods. The project specifically aims at identifying the noise exposure patterns that most strongly affect individuals during sleep and that may result in long-term health consequences, in particular, in cardiovascular diseases and metabolic syndrome. Besides the effect of noise exposure, the role of individual characteristics such as age and gender, noise sensitivity and genetic predispositions will be elucidated.Methods: This interdisciplinary study consists of three sub-projects. Sub-project 1 focuses on the modelling of road, railway and aircraft noise exposure and its effects on annoyance and coping responses in the Swiss population. Exposure modelling will be considerably refined to reflect not only average exposure, but additional exposure characteristics such as the degree of intermittence of noise events that we hypothesise to be a relevant predictor of detrimental effects of noise during sleep. Furthermore, realistic transportation noise exposure scenarios will be compiled in Sub-project 1 and played back in sleep laboratory experiments in Sub-project 2. In Sub-project 2 acute (e.g. awakening reactions) and short-term (e.g. cardiometabolic and cognitive effects on the subsequent day) consequences of nocturnal noise exposure scenarios will be investigated in a well controlled environment by employing a counterbalanced randomised cross-over design with 48 volunteers constantly monitored during 6 nights and 5 days. In Sub-project 3 data of two on-going large SNF-funded population-based epidemiological studies (SAPALDIA biobank and Swiss National Cohort) will be used to investigate long-term cardiometabolic risk with high statistical power and by considering relevant co-factors. The three Sub-projects are designed to closely interact in an interdisciplinary manner. Sub-project 1 will provide the noise exposure scenarios and exposure set-up for Sub-project 2 and the exposure modelling for Sub-project 3. The same cardiometabolic outcomes of Sub-project 3 available from several thousand SAPALDIA study participants will also be collected in Sub-project 2 with high time resolution under controlled experimental conditions. Significance: Mutually combining human experimental and epidemiological research to systematically address acute, short- and long-term noise effects on sleep and cardiometabolic outcomes is an asset of this study and has rarely been done in noise effect research before. Experimental research allows for evaluating the effects of well defined acoustical noise exposure scenarios in a controlled environment on carefully selected, representative individuals. The use of ongoing large-scale population-based epidemiologic studies enables cost-efficiently addressing the full range of variability in the population and in exposure circumstances that occur in our environment. This will be the first study on transportation noise effects that considers genetic variations, which will provide a better understanding of relevant biological pathways. Systematic consideration of transportation noise exposure levels as well as other noise characteristics, such as the distribution of noise events during the night, is a unique feature of this project and is highly relevant for adequate regulation of noise emissions of different transportation modes. It is estimated that Switzerland, by about 2020, will have invested a substantial >5 billion Swiss francs in noise abatement measures. Thus, beyond scientific there is a high policy interest in our research questions and the results of this project are expected to have a broad impact by revealing evidence-based measures of action in order to most effectively invest these resources.
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