Project

Back to overview

Morbidity patterns and transmission dynamics of neglected tropical diseases in semi-arid and humid Africa

English title Morbidity patterns and transmission dynamics of neglected tropical diseases in semi-arid and humid Africa
Applicant Zinsstag Jakob
Number 123185
Funding scheme ProDoc
Research institution Swiss Tropical and Public Health Institute Medical Services and Diagnostic Universität Basel
Institution of higher education University of Basel - BS
Main discipline Methods of Epidemiology and Preventive Medicine
Start/End 01.11.2008 - 29.02.2012
Approved amount 397'750.00
Show all

All Disciplines (2)

Discipline
Methods of Epidemiology and Preventive Medicine
Public Health and Health Services

Keywords (9)

neglected tropical diseases; zoonoses; morbidity patterns; transmission dynamics; metabolic profiling; mobile nomadic populations; demographic surveillance; Chad; Côte d'Ivoire

Lay Summary (English)

Lead
Lay summary
Background: The general health of populations has been improved substantially in the last decades and child mortality could be reduced in developing countries. However, progress remains uneven and there are growing differences in mortality and illnesses in different parts of the world. For example, communicable diseases and mother and child conditions are particularly severe in the tropics and subtropics, and impair the socio-economic development. Further improving the health of these population groups could save millions of healthy life years and reduce poverty, and hence contribute to achieving the objectives set by the United Nations for 2015, the so-called Millennium Development Goals (MDGs). Certain MDGs are addressed by global alliances and partnerships; e.g. for the control of f HIV/AIDS, tuberculosis and malaria. However there exist many other parasitic and communicable diseases that are often neglected. Some of these “neglected tropical diseases” are transmissible between animals and humans. Our project aims at a better understanding of the transmission and control of NTDs in Central and West Africa.Goal and objectives: Prior to being able to propose effective ways for the control of NTDs, we need to deepen our understanding how people get ill from NTDs and how they are transmitted to them. Many of these diseases are closely linked to how people live together and to their environment.Approach: This requires following-up larger groups of women, men and children for a longer time period. This means that people are seen repeatedly by competent medical personnel to record their health. A further complication is that some of these people do not live all the time at the same place, but migrate with their animals for the search of food and water. We therefore envisage to follow-up two groups of people, a highly mobile population in Chad, and a rural sedentary population in south-central Côte d’Ivoire. Observing whole population groups on a regular basis for several years can be effectively done within a so-called “demographic surveillance system” (DSS). At any encounter people will be asked if the consent to a clinical examination and the collection of specimens for the detection of agents of disease. A tool for assessing illnesses due to NTDs (morbidity tool) will be developed and tested for its accuracy.Outcome: Once solid knowledge will be established on the most important illnesses, locally adapted interventions can be designed and implemented in accordance to the identified needs (e.g. mass treatment against worms). The established DSS can be further used for long-term monitoring of many other health- and poverty-related issues.
Direct link to Lay Summary Last update: 21.02.2013

Responsible applicant and co-applicants

Employees

Publications

Publication
Global burden of human food-borne trematodiasis: a systematic review and meta-analysis
Furst T, Keiser J, Utzinger J (2012), Global burden of human food-borne trematodiasis: a systematic review and meta-analysis, in LANCET INFECTIOUS DISEASES, 12(3), 210-221.
Prevalence and risk factors of helminths and intestinal protozoa infections among children from primary schools in western Tajikistan
Matthys B, Bobieva M, Karimova G, Mengliboeva Z, Jean-Richard V, Hoimnazarova M, Kurbonova M, Lohourignon LK, Utzinger J, Wyss K (2011), Prevalence and risk factors of helminths and intestinal protozoa infections among children from primary schools in western Tajikistan, in PARASITES & VECTORS, 4(195), epub-epub.
Effect of Schistosomiasis and Soil-Transmitted Helminth Infections on Physical Fitness of School Children in Cote d'Ivoire
Muller I, Coulibaly JT, Furst T, Knopp S, Hattendorf J, Krauth SJ, Stete K, Righetti AA, Glinz D, Yao AK, Puhse U, N'Goran EK, Utzinger J (2011), Effect of Schistosomiasis and Soil-Transmitted Helminth Infections on Physical Fitness of School Children in Cote d'Ivoire, in PLOS NEGLECTED TROPICAL DISEASES, 5(7), e1239-e1239.
Questionnaire-based approach to assess schoolchildren's physical fitness and its potential role in exploring the putative impact of helminth and Plasmodium spp. infections in Cote d'Ivoire
Furst T, Muller I, Coulibaly JT, Yao AK, Utzinger J, N'Goran EK (2011), Questionnaire-based approach to assess schoolchildren's physical fitness and its potential role in exploring the putative impact of helminth and Plasmodium spp. infections in Cote d'Ivoire, in PARASITES & VECTORS, 24(4), 116-116.
Effect of an armed conflict on relative socioeconomic position of rural households: case study from western Côte d'Ivoire.
Fürst Thomas, Tschannen Andres B, Raso Giovanna, Acka Cinthia A, de Savigny Don, Girardin Olivier, N'goran Eliézer K, Utzinger Jürg (2010), Effect of an armed conflict on relative socioeconomic position of rural households: case study from western Côte d'Ivoire., in Emerging themes in epidemiology, 7(1), 6-6.
Self-rated quality of life and school performance in relation to helminth infections: case study from Yunnan, People's Republic of China
Ziegelbauer K, Steinmann P, Zhou H, Du ZW, Jiang JY, Furst T, Jia TW, Zhou XN, Utzinger J (2010), Self-rated quality of life and school performance in relation to helminth infections: case study from Yunnan, People's Republic of China, in PARASITES & VECTORS, 3(61), epub-epub.
Dynamics of Socioeconomic Risk Factors for Neglected Tropical Diseases and Malaria in an Armed Conflict
Furst T, Raso G, Acka CA, Tschannen AB, N'Goran EK, Utzinger J (2009), Dynamics of Socioeconomic Risk Factors for Neglected Tropical Diseases and Malaria in an Armed Conflict, in PLOS NEGLECTED TROPICAL DISEASES, 3(9), e513-e513.

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
Young scientists- is Switzerland doing enough 11.11.2011 Bern, Switzerland
Health for mobile pastoralists 15.06.2011 Addis Ababa


Knowledge transfer events

Active participation

Title Type of contribution Date Place Persons involved
Forum Zoonoses et Interventions Intersectorielles. Programme d’Appui Intersectoriel aux communautés nomades en république du Tchad 17.05.2011 Dougia, Chad


Communication with the public

Communication Title Media Place Year
Media relations: print media, online media "One health" für Mensch und Tier Uni Nova German-speaking Switzerland 01.04.2012

Associated projects

Number Title Start Funding scheme
141246 Systems epidemiology of human schistosomiasis and livestock fascioliasis in sub-Saharan Africa 01.08.2012 Project funding (Div. I-III)
170113 Transmission dynamics and hybridization of human and animal trematodes in sub-Saharan Africa 01.01.2017 Project funding (Div. I-III)

-