Institute

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Name

Centre Integratif de Genomique Faculté de Biologie et Médecine Université de Lausanne

Address Centre Integratif de Genomique Faculté de Biologie et Médecine Université de Lausanne
Chemin des Boveresses 155
1066
CH-Epalinges
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Projects

Responsible applicant Institution of higher education Start End date Funding scheme

The role of protein kinase C isoforms in cell transformation and programmed cell death
Borner Christoph University of Fribourg - FR 01.01.1994 31.12.1996 Project funding (Div. I-III)

Regulation of B cell differentiation in the peripheral lymph node
Acha-Orbea Hans University of Lausanne - LA 01.09.2000 30.09.2005 Project funding (Div. I-III)

Antigen presentation by macrophages: study with defined peptides and in an experimental model of infection.
Mauël Jacques University of Lausanne - LA 01.10.1979 30.09.1982 Project funding (Div. I-III)

Etudes sur le complément et les antigenes tumoraux
Isliker Henri University of Lausanne - LA 01.10.1977 30.09.1979 Project funding (Div. I-III)

Prevention of systemic spread of a retrovirus after systemic mucosal or sexual infection: the mouse mammary tumor virus model
Krähenbühl Jean-Pierre University of Lausanne - LA 01.01.1994 31.12.1996 Project funding (special)

Study of the functional and structural membrane polarity of epithelial cells involved in mucosal immunity or sodium trans- port
Krähenbühl Jean-Pierre University of Lausanne - LA 01.10.1989 30.09.1993 Project funding (Div. I-III)

Identification of the mode of action of Bcl-2 family members
Borner Christoph University of Fribourg - FR 01.01.2000 30.09.2003 Project funding (Div. I-III)

Function of the TNF family ligands BAFF, APRIL and EDA
Schneider Pascal University of Lausanne - LA 01.10.2005 30.09.2008 Project funding (Div. I-III)

Analysis of the signaling pathway regulating T-cell receptor-induced NF-kB activation and lymphocyte proliferation
Thome-Miazza Margot University of Lausanne - LA 01.05.2004 30.04.2008 SNSF Professorships

Mechanism of complement and T-effector cell mediated cytolysis
Tschopp Jurg University of Lausanne - LA 01.10.1985 30.09.1988 Project funding (Div. I-III)

The role of protein kinase C isoforms in cell transformation and programmed cell death (START-Beitrag)
Borner Christoph University of Fribourg - FR 01.11.1993 31.10.2000 START

Cell death in leishmania parasites
Fasel Nicolas Joseph University of Lausanne - LA 01.04.2007 30.06.2010 Project funding (Div. I-III)

Metabolic labelling and specific mass spectrometry : tools to study changes in protein expression
Quadroni Manfredo Riccardo University of Lausanne - LA 01.10.2005 30.09.2009 Project funding (Div. I-III)

Repair of DNA Crosslink-Associated Replication Intermediates in Human Cells
Constantinou Angelos University of Lausanne - LA 01.05.2004 30.04.2008 SNSF Professorships

Immunochemical and functional studies of cell membrane proteins
Bron Claude University of Lausanne - LA 01.10.1980 30.09.1983 Project funding (Div. I-III)

Post-translational modifications of cell surface antigens
Fasel Nicolas Joseph University of Lausanne - LA 01.04.1993 31.03.1996 Project funding (Div. I-III)

PROCESSING AND PRESENTATION OF MHC CLASS I AND CLASS II RESTRICTED PEPTIDES.
Corradin Giampietro University of Lausanne - LA 01.10.1992 31.03.1999 Project funding (Div. I-III)

Transport of macromolecules in epithelial cells and its hormonal control
Krähenbühl Jean-Pierre University of Lausanne - LA 01.10.1980 30.09.1983 Project funding (Div. I-III)

Structural and functional studies of lymphocyte membrane proteins
Bron Claude University of Lausanne - LA 01.10.1986 30.09.1989 Project funding (Div. I-III)

Réunions scientifiques de l'USSBE/USGEB
Monard Denis University of Lausanne - LA 01.04.1997 31.03.2000 Scientific Conferences

Identification of genetic markers associated with virulence of Leishmania Viannia
Fasel Nicolas Joseph University of Lausanne - LA 01.04.2000 31.03.2003 Research Partnerships with Developing Countries

Mechanisms of tumour supression by the FA/BRCA pathway
Constantinou Angelos University of Lausanne - LA 01.05.2008 30.04.2010 SNSF Professorships

Analysis of intracellular membrane fusion using yeast vacuoles as a model system: Role of VTC proteins and VO in the late phase
Mayer Andreas University of Lausanne - LA 01.11.2003 31.10.2006 Project funding (Div. I-III)

Mechanisms of sorting in polarized epithelial cells
Hunziker Walter University of Lausanne - LA 01.10.1992 30.09.1997 Project funding (Div. I-III)

Analysis of SNARE-dependent Membrane Fusion
Mayer Andreas University of Lausanne - LA 01.10.2006 30.09.2009 Project funding (Div. I-III)

Plasmodium falciparum: genome based antigen discovery and vaccine development
Corradin Giampietro University of Lausanne - LA 01.04.2006 30.06.2009 Project funding (Div. I-III)

Swiss Trypanosomatid meeting
Fasel Nicolas Joseph University of Lausanne - LA 01.01.1996 30.06.1996 Scientific Conferences

Etudes sur le complement et les antigenes tumoraux
Isliker Henri University of Lausanne - LA 01.10.1975 30.09.1977 Project funding (Div. I-III)

Design of effective oligomerization peptide modules made up of alpha-helical coiled coils and their poential biomedical appli- cations
Kaiava Andrei University of Lausanne - LA 01.04.1996 31.03.1998 Project funding (Div. I-III)

Function of the TNF family ligands EDA, BAFF and APRIL
Schneider Pascal University of Lausanne - LA 01.10.2002 30.09.2005 Project funding (Div. I-III)

T cell antigenic structures: Biochemical characterization and interaction with histocompatibility antigens and T cell antigen receptors
Corradin Giampietro University of Lausanne - LA 01.10.1986 30.09.1989 Project funding (Div. I-III)

Protein Analysis Facility of the University of Lausanne : upgrade of an LTQ-Orbitrap mass spectrometer
Quadroni Manfredo Riccardo University of Lausanne - LA 01.09.2008 31.08.2009 R'EQUIP

A Quantitative Study of T Lymphocyte Antigen Recognition. (subside de recherche lié au SCORE A)
Valitutti Salvatore University of Lausanne - LA 01.05.1997 30.04.2000 Project funding (Div. I-III)

Molecular dynamics of contact sites between T lymphocytes and antigen presenting cells.
Valitutti Salvatore University of Lausanne - LA 01.05.2000 30.04.2001 Project funding (Div. I-III)

Engineering of humanized pathogen-specific secretory IgA or IgA like antibodies
Krähenbühl Jean-Pierre University of Lausanne - LA 01.01.1996 30.09.1997 Swiss Priority Programmes (SPPs)

Signal transduction by a glycosylphosphatidylinositol (GPI)- an- chored membrane protein of lymphocytes
Bron Claude University of Lausanne - LA 01.10.1997 30.09.2000 Project funding (Div. I-III)

Investigating the role of fanconi anemia protein FANCM in the cellular response to blocked replication
Glaser Sarah University of Lausanne - LA 01.10.2007 30.09.2009 Marie Heim-Voegtlin grants

The molecular mechanisms underlying cell death protection by Bcl-2 and protein kinase C alpha
Borner Christoph University of Fribourg - FR 01.01.1997 31.07.2000 Project funding (Div. I-III)

Lymphocyte-mediated apoptosis
Tschopp Jurg University of Lausanne - LA 01.10.1996 30.09.2001 Project funding (Div. I-III)

Study of the structural anf functional polarity of epitheli- al cells involved in mucosal immunity and sodium transport
Krähenbühl Jean-Pierre University of Lausanne - LA 01.10.1986 30.09.1989 Project funding (Div. I-III)

Notch signaling as a key determinant of Epithelial-Mesenchymal interactions in the skin
Dotto Gian-Paolo University of Lausanne - LA 01.10.2008 30.09.2011 Project funding (Div. I-III)

MARCKS-related protein (MRP) in normal and Leishmania-infected macrophages: Studies with cell-permeable peptides
Mauël Jacques University of Lausanne - LA 01.10.2000 31.08.2002 Project funding (Div. I-III)

Mechanisms of cytolytic immune effector systems
Tschopp Jurg University of Lausanne - LA 01.10.1991 30.09.1996 Project funding (Div. I-III)

Cell death in Leishmania Parasites.
Fasel Nicolas Joseph University of Lausanne - LA 01.04.2004 31.03.2007 Project funding (Div. I-III)

Using a new dendritic cell tumor model in the mouse for probing dendritic cell biology and cancer
Acha-Orbea Hans University of Lausanne - LA 01.10.2010 30.09.2013 Project funding (Div. I-III)

Engineering of Secretory IgA: antibodies that protect mucosal surfaces
Krähenbühl Jean-Pierre University of Lausanne - LA 01.10.1992 31.12.1995 Swiss Priority Programmes (SPPs)

Biological and biochemical studies on Leishmania parasites and their interaction with host cells
Mauël Jacques University of Lausanne - LA 01.10.1988 30.09.1991 Project funding (Div. I-III)

Implication of Death Receptors in the Graft-Versus-Leukemia Effect (zu SCORE B)
Kovacsovics-Bankowsk Magdalena University of Lausanne - LA 01.01.1998 30.09.2001 Project funding (Div. I-III)

Mechanism of Branch Migration and Holliday Junction Resolution in Mammalian Cells
Constantinou Angelos University of Lausanne - LA 01.04.2003 30.09.2006 Project funding (Div. I-III)

Signaling pathways leading to apoptosis and inflammation
Tschopp Jurg University of Lausanne - LA 01.10.2006 30.09.2009 Project funding (Div. I-III)

Radiolabeled monoclonal antibodies for diagnosis and treat- ment of colorectal carcinomas - experimental and clinical studies
Mach Jean-Pierre University of Lausanne - LA 01.04.1991 31.03.1994 Project funding (Div. I-III)

La calcineurine dans le contrôle de la croissance-différenciation
Dotto Gian-Paolo University of Lausanne - LA 01.10.2003 30.09.2008 Project funding (Div. I-III)

Immunochemical and functional studies of cell membrane proteins
Bron Claude University of Lausanne - LA 01.10.1977 30.09.1980 Project funding (Div. I-III)

Role of Protein Kinase C isoforms in cellular signalling; regulation by interaction with lipids and proteins
Quest Andrew F.G. University of Lausanne - LA 01.10.1994 30.09.1997 Project funding (Div. I-III)

TNF family ligands BAFF, APRIL and EDA
Schneider Pascal University of Lausanne - LA 01.10.2011 30.09.2014 Project funding (Div. I-III)

Implication of Death Receptors in the Graft-Versus-Leukemia Effect (SCORE B)
Kovacsovics-Bankowsk Magdalena University of Lausanne - LA 01.01.1998 30.09.2001 Ambizione

Signaling pathways leading to apoptosis and inflammation
Schneider Pascal University of Lausanne - LA 01.10.2009 30.09.2012 Project funding (Div. I-III)

Apoptosis or the intracellular suicidal program (MHV)
Schärer-Züblin Esther University of Lausanne - LA 01.01.1992 31.12.1994 Marie Heim-Voegtlin grants

Protein transport, membrane biogenesis, membrane traffic and their hormonal regulation in epithelia
Krähenbühl Jean-Pierre University of Lausanne - LA 01.10.1983 30.09.1986 Project funding (Div. I-III)

Structural and functional studies of lymphocyte membrane proteins
Bron Claude University of Lausanne - LA 01.10.1989 30.09.1994 Project funding (Div. I-III)

Mechanism of Cytolytic T Lymphocyte- and Complement-Mediated Cytolysis
Tschopp Jurg University of Lausanne - LA 01.10.1988 30.09.1991 Project funding (Div. I-III)

Induction of a broad cytotoxic T-lymphocyte and humoral immune response based on HIV peptides encapsulated in microspheres
Corradin Giampietro University of Lausanne - LA 01.01.2000 28.02.2001 Project funding (special)

Role of dendritic cell subsets in Leishmania infection
Acha-Orbea Hans University of Lausanne - LA 01.05.2010 30.09.2013 ProDoc

Etudes sur le complément et les antigènes tumoraux.
Isliker Henri University of Lausanne - LA 01.10.1979 30.09.1982 Project funding (Div. I-III)

Antigen recognition by class I and class II restricted T cells
Corradin Giampietro University of Lausanne - LA 01.10.1989 30.09.1992 Project funding (Div. I-III)

Biological and biochemical studies on Leishmania parasites and their interaction with host cells
Mauël Jacques University of Lausanne - LA 01.10.1991 30.09.1994 Project funding (Div. I-III)

Analysis of death-inducing signalling complexes (DISCs) by proteomics techniques
Quadroni Manfredo Riccardo University of Lausanne - LA 01.10.2000 31.01.2004 Project funding (Div. I-III)

Antigen presentation to major histocompatibilty complex class I and II restricted lymphocytes: a malaria case
Corradin Giampietro University of Lausanne - LA 01.04.1999 31.03.2002 Project funding (Div. I-III)

Protein traffic in polarized epithelial cells
Hunziker Walter University of Lausanne - LA 01.10.1997 30.09.2000 Project funding (Div. I-III)

Role of lipid rafts in GPI-anchored and transmembrane receptors- mediated lymphocyte signaling
Bron Claude University of Lausanne - LA 01.10.2000 31.10.2003 Project funding (Div. I-III)

Synergic signals for cytokine production in dendritic cells
Acha-Orbea Hans University of Lausanne - LA 01.04.2010 31.07.2013 Sinergia

Swiss Trypanosomatid meeting
Fasel Nicolas Joseph University of Lausanne - LA 01.01.1995 30.06.1995 Scientific Conferences

Signal transduction by a glycosylphosphatidyl inositol (GPI)- an-chored membrane protein of lymphocytes
Bron Claude University of Lausanne - LA 01.10.1994 30.09.1997 Project funding (Div. I-III)

Strucural and functional studies of protozoan proteins
Fasel Nicolas Joseph University of Lausanne - LA 01.11.1996 31.03.2000 Project funding (Div. I-III)

Mechanisms of sorting in polarized epithelial cells (START-Bei- trag)
Hunziker Walter University of Lausanne - LA 01.09.1992 31.08.1999 START

Radiolabeled monoclonal antibodies for diagnosis and treat- ment of colorectal carcinomas - experimental and clinical studies
Mach Jean-Pierre University of Lausanne - LA 01.10.1987 31.03.1991 Project funding (Div. I-III)

Physiology and pathophysiology of the activated macrophage: mechanisms of antimicrobial activity and atherogenesis
Mauël Jacques University of Lausanne - LA 01.10.1994 30.09.1997 Project funding (Div. I-III)

Development of new stategies for radioimmunotherapy of B-cell lymphoma and colorectal or breast carcinomas with recombinant antibodies
Mach Jean-Pierre University of Lausanne - LA 01.01.1999 31.12.2001 Project funding (special)

Elicitation of cytotoxic T responses specific for constant regions of HIV proteins
Corradin Giampietro University of Lausanne - LA 01.10.1992 29.02.1996 Project funding (special)

Identification of antigens expressed by P. vivax pre-erythrocyticstages. (MHV-Beitrag)
Romero F. Jackeline University of Lausanne - LA 01.01.1997 31.12.2000 Marie Heim-Voegtlin grants

Immunochemical and Functional Studies of Lymphocyte Membrane Proteins.
Bron Claude University of Lausanne - LA 01.10.1983 30.09.1986 Project funding (Div. I-III)

Mutual control of membrane fusion and membrane fission components in vesicular trafficking
Peters Christopher University of Lausanne - LA 01.04.2005 31.03.2008 Project funding (Div. I-III)

Function of the TNF family ligands BAFF, APRIL and EDA
Schneider Pascal University of Lausanne - LA 01.10.2008 30.09.2011 Project funding (Div. I-III)

The development of antagonists of CD95 ligand
Schneider Pascal University of Lausanne - LA 01.04.1996 30.09.2000 Project funding (special)

Molecular basis for the activity of the first and last components of complement (C)
Tschopp Jurg University of Lausanne - LA 01.10.1982 30.09.1985 Project funding (Div. I-III)

Biological and Biochemical studies on Leishmania Parasites
Mauël Jacques University of Lausanne - LA 01.10.1982 30.09.1985 Project funding (Div. I-III)

Molecular cross-talk between epithelial cells and pathogenic microorganisms (Wissenschaftliche Tagung)
Krähenbühl Jean-Pierre University of Lausanne - LA 01.07.1991 31.12.1991 Scientific Conferences

The role of transepithelial transport in passive and active mucosal immunization
Krähenbühl Jean-Pierre University of Lausanne - LA 01.10.1993 30.09.1996 Project funding (Div. I-III)

Analysis of SNARE-dependent Membrane Fusion
Mayer Andreas University of Lausanne - LA 01.10.2009 30.09.2012 Project funding (Div. I-III)

The ligands of the class II major histocompatibility complex- restricted T lymphocytes: structure and biogenesis
Demotz Stéphane University of Lausanne - LA 01.10.1994 31.03.1998 Project funding (Div. I-III)

Strucural and functional analysis of Leishmania Proteins
Fasel Nicolas Joseph University of Lausanne - LA 01.03.2000 28.02.2003 Project funding (Div. I-III)

Characterization of the TNF family ligands BAFF and APRIL
Schneider Pascal University of Lausanne - LA 01.10.2000 30.09.2002 Project funding (Div. I-III)

T zone stromal cells in secondary lymphoid tissues and their roles in dendritic cell retention and T cell homeostasis
Luther Sanjiv University of Lausanne - LA 01.08.2007 30.04.2010 SNSF Professorships

Using a new dentritic cell tumor model in the mouse for probing dentritic cell biology and cancer
Acha-Orbea Hans University of Lausanne - LA 01.10.2005 30.09.2010 Project funding (Div. I-III)

Etudes immunochimiques de membranes cellulaires. Synthese et transport des immunoglobulines a de secretion
Bron Claude University of Lausanne - LA 01.10.1975 30.09.1977 Project funding (Div. I-III)

Signaling pathways leading to apoptosis and inflammation
Tschopp Jurg University of Lausanne - LA 01.10.2001 30.09.2006 Project funding (Div. I-III)

Quantitative proteome-level analysis of protein synthesis and degradation rates
Quadroni Manfredo Riccardo University of Lausanne - LA 01.01.2010 28.02.2013 Project funding (Div. I-III)

Apoptosis or the intracellular suicidal program
Schärer-Züblin Esther University of Lausanne - LA 01.10.1992 31.03.1995 Project funding (Div. I-III)

Analysis of the signaling pathway regulating T-cell receptor-induced NF-kB activation and lymphocyte proliferation
Thome-Miazza Margot University of Lausanne - LA 01.05.2008 30.04.2010 SNSF Professorships

Bilogical and biochemical studies on leishmania parasites and their interactions with the host
Mauël Jacques University of Lausanne - LA 01.10.1985 30.09.1988 Project funding (Div. I-III)

The Leishmania-macrophage interaction: Intracellular parasite killing and effect of infection on macrophage physiology
Mauël Jacques University of Lausanne - LA 01.10.1997 30.09.2000 Project funding (Div. I-III)

Role of Protein Kinase C isoforms in cellular signalling; regulation by interaction with lipids and proteins
Quest Andrew F.G. University of Lausanne - LA 01.10.1997 30.09.2000 Project funding (Div. I-III)

Identification and Molecular Characterization of Endogenous Activators of the Inflammasome: Probing the Danger Theory of Immunity
Menu Philippe University of Lausanne - LA 01.03.2007 28.02.2010 MD-PhD fellowships (funded by SNSF)
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