Institute

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Name

Friedrich Miescher Institute for Biomedical Research

Address Friedrich Miescher Institute for Biomedical Research
Maulbeerstrasse 66
4058
CH-Basel
Website http://www.fmi.ch
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Projects

Responsible applicant Institution of higher education Start End date Funding scheme

Improving CRISPR-Cas9 efficiency using small molecules to modulate chromatin structure
Seeber Andrew University of Basel - BS 01.08.2017 31.07.2018 Bridge - Proof of Concept

Réunions scientifiques de l'USSBE (USGEB)
Rusconi Sandro Institute Friedrich Miescher - FMI 01.04.2000 30.09.2004 Scientific Conferences

Interactions between (1) Cytoskeleton and Membrane (2) Membrane and Matrix and (3) Matrix Recognition Molecules among themselves
Burger Max M. Institute Friedrich Miescher - FMI 01.04.1986 30.09.1988 Project funding (Div. I-III)

The role of Lsm proteins in heterochromatic gene silencing
Mattout Anna Institute Friedrich Miescher - FMI 01.06.2014 30.09.2016 Marie Heim-Voegtlin grants

Roles of chromatin in genome stability
Gasser Susan Institute Friedrich Miescher - FMI 01.01.2018 31.12.2020 Project funding (Div. I-III)

Protein dephosphorylation workshop
Hemmings Brian Institute Friedrich Miescher - FMI 01.01.1996 30.06.1996 Scientific Conferences

Single molecule characterization of transcription factor binding at mouse cis-regulatory regions
Krebs Arnaud Institution abroad - IACH 01.01.2016 31.12.2018 Ambizione

Cell-Cell Interactions: A. In a Model System for Neurobiology (Marine Sponges) B. Neuromuscular Interactions in Mouse
Burger Max M. Institute Friedrich Miescher - FMI 01.10.1976 30.09.1979 Project funding (Div. I-III)

Post-transcriptional gene regulation in development: the function of LIN-41/TRIM71
Grosshans Helge Institute Friedrich Miescher - FMI 01.06.2016 31.10.2019 Project funding (Div. I-III)

Chemical Screen on Hydra Regeneration
Tsiairis Charisios Institute Friedrich Miescher - FMI 01.07.2019 30.06.2022 Project funding (Div. I-III)

Molecular mechanisms of breast tumorigenesis, metastasis, and resistance to therapy in tumors with a mutated PI3K pathway
Bentires-Alj Mohamed University of Basel - BS 01.12.2016 30.11.2019 Project funding (Div. I-III)

EPIGENETIC CONTROL OF EARLY MOUSE DEVELOPMENT
Peters Antoine Hendrik Felix Marie Institute Friedrich Miescher - FMI 01.04.2009 31.03.2012 Project funding (Div. I-III)

Mapping the neuronal code of fear
Gründemann Jan Institute Friedrich Miescher - FMI 01.01.2015 31.12.2017 Ambizione

An image-based systems biology approach to symmetry breaking in collective cell behavior
Liberali Prisca Institute Friedrich Miescher - FMI 01.07.2015 30.06.2019 SNSF Professorships

Analysis of the host range of Agrobacterium
Relic Biserka Institute Friedrich Miescher - FMI 01.01.1995 31.12.1996 Swiss Priority Programmes (SPPs)

Transport and local translation of mRNAs in neurons
Chao Jeffrey Institute Friedrich Miescher - FMI 01.01.2015 31.12.2017 Project funding (Div. I-III)

Connecting visual and cognitive brain circuits
Roska Botond University of Basel - BS 01.01.2019 31.12.2022 Project funding (Div. I-III)

Intracellular communications in plants - Mechanism of intra- and intercellular RNA transport
Heinlein Manfred Institute Friedrich Miescher - FMI 01.03.2003 31.03.2006 SNSF Professorships

Roles of the protein tyrosine phosphatase SHP2 in metastatic breast cancer
Bentires-Alj Mohamed Institute Friedrich Miescher - FMI 01.07.2013 30.11.2016 Project funding (Div. I-III)

An image-based systems biology approach to symmetry breaking in collective cell behavior.
Liberali Prisca Institute Friedrich Miescher - FMI 01.07.2019 30.06.2021 SNSF Professorships

role of the deacetylases HDAC-1 and HDAC-2 for cell cycle progression
Matthias Patrick Institute Friedrich Miescher - FMI 01.09.2009 31.03.2013 Project funding (Div. I-III)

Neural Substrates of Pavlovian Fear Conditioning: Synaptic and Cellular Mechanisms of Associative Plasticity in the Lateral Amygdala
Lüthi Andreas Institute Friedrich Miescher - FMI 01.04.2003 30.11.2004 SNSF Professorships

Modulation of Neural Circuits and Behavior
Friedrich Rainer Institute Friedrich Miescher - FMI 01.04.2019 30.06.2019 Scientific Exchanges

Controlling fear: function and plasticity of inhibitory circuits in the amygdala
Lüthi Andreas Institute Friedrich Miescher - FMI 01.10.2010 30.09.2013 Project funding (Div. I-III)

Molecular mechanism of meiotic recombination in plants
Paszkowski Jerzy Institute Friedrich Miescher - FMI 01.04.1990 31.03.1992 Project funding (Div. I-III)

Frontiers in Biomedical Research-40th Anniversary FMI
Matthias Patrick Institute Friedrich Miescher - FMI 01.09.2010 28.02.2011 Scientific Conferences

Translational control of totipotency in the animal germ line
Ciosk Rafal Institute Friedrich Miescher - FMI 01.01.2011 31.12.2013 Project funding (Div. I-III)

A. Metastasis: The Relevance of Cell Surface Carbohydrate Changes. B. Molecular Aspects of Cell-Cell Recognition and Assembly of Cells into Organs
Burger Max M. Institute Friedrich Miescher - FMI 01.10.1979 30.09.1982 Project funding (Div. I-III)

Function of dopaminergic neurons in neuronal circuits of the zebrafish olfactory system
Zhang Schärer Yanping Institute Friedrich Miescher - FMI 01.02.2009 31.01.2011 Marie Heim-Voegtlin grants

Role of the bone marrow in breast cancer metastasis and therapy response
Hynes Nancy E. Institute Friedrich Miescher - FMI 01.01.2012 31.12.2013 Project funding (Div. I-III)

Long-range chromatin organization and genome stability
Gasser Susan Institute Friedrich Miescher - FMI 01.01.2015 31.12.2017 Project funding (Div. I-III)

Sensorimotor learning in mouse visual cortex
Keller Georg Institute Friedrich Miescher - FMI 01.01.2014 31.12.2016 Project funding (Div. I-III)

Control of translation of specific viral and cellular mRNAs.
Hohn Thomas University of Berne - BE 01.09.2001 30.04.2004 SCOPES

Utilization of viral replicases for selective amplification of foreign mRNAs in transgenic plants (Switzerland/US cooperative science project)
Paszkowski Jerzy Institute Friedrich Miescher - FMI 01.09.1989 31.08.1993 Project funding (special)

Encoding of Associative Fear Memory in Identified Neuronal Circuits of Auditory Cortex
Letzkus Johannes Jakob Institute Friedrich Miescher - FMI 01.12.2010 31.08.2014 Ambizione

Homologous DNA recombination in plants
Paszkowski Jerzy Institute Friedrich Miescher - FMI 01.04.1988 31.12.1992 Project funding (Div. I-III)

Brain rewiring after vision loss and rehabilitation
Trenholm Stuart Institute Friedrich Miescher - FMI 01.09.2016 31.08.2017 Ambizione

The contribution of extracellular matrix to epigenetic regulation of cell fate in stem cell niches
Hynes Nancy E. Institute Friedrich Miescher - FMI 01.10.2014 30.09.2017 Project funding (Div. I-III)

Studies on Memo: a novel protein with a role in cancer and aging
Hynes Nancy E. Institute Friedrich Miescher - FMI 01.01.2009 30.04.2012 Project funding (Div. I-III)

Bonus of Excellence - Transcription factor binding as a function of chromatin
Schübeler Dirk Institute Friedrich Miescher - FMI 01.08.2018 31.07.2021 Project funding (Div. I-III)

Role of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the regulation of immune cell development, maintenance and function
Matthias Patrick Institute Friedrich Miescher - FMI 01.10.2012 30.09.2015 Project funding (Div. I-III)

Establishment of chromatin states in mouse sperm and their relevance for paternal epigenetic inheritance
Peters Antoine Hendrik Felix Marie Institute Friedrich Miescher - FMI 01.10.2013 30.09.2016 Project funding (Div. I-III)

Transcriptional and epigenetic regulation of precerebellar neuron migration and connectivity
Rijli Filippo Institute Friedrich Miescher - FMI 01.01.2014 30.09.2017 Project funding (Div. I-III)

The role of the E2F transcription factor in cell cycle and growthcontrol (START-Beitrag)
Krek Wilhelm Institute Friedrich Miescher - FMI 01.09.1995 31.08.2000 START

Circuit mechanisms of learning and memory
Caroni Pico Institute Friedrich Miescher - FMI 01.09.2015 31.01.2017 Project funding (Div. I-III)

Role of miRNAs in the retinal bipolar cell post-synaptic response
Cronin Therese Institute Friedrich Miescher - FMI 01.02.2012 31.01.2013 Marie Heim-Voegtlin grants

From extracellular matrix to cytoskeleton to nucleus: mechanotransduction in cancer progression
Chiquet-Ehrismann Ruth Institute Friedrich Miescher - FMI 01.04.2011 31.03.2014 Project funding (Div. I-III)

Targeting the Kinome III
Bentires-Alj Mohamed Institute Friedrich Miescher - FMI 01.09.2014 28.02.2015 Scientific Conferences

Analysis of class I histone deacetylases in B cell development and antibody diversification
Matthias Patrick Institute Friedrich Miescher - FMI 01.10.2017 30.09.2020 Project funding (Div. I-III)

Linking retinal and cortical visual processing
Roska Botond Institute Friedrich Miescher - FMI 01.10.2012 30.09.2015 Project funding (Div. I-III)

Analysis of DNA polymerase stability at the replication fork in yeast mutants
Davoodi Vijeh Motlagh Niloofar Institute Friedrich Miescher - FMI 01.10.2007 31.12.2007 International short research visits

The evolutionary ecology of infectious pathogens
Bonhoeffer Sebastian Institute Friedrich Miescher - FMI 01.03.2001 28.02.2005 SNSF Professorships

Studies on the role of RNAi and other RNA turnover mechanisms in initiation and maintenance of heterochromatin
Bühler Marc Institute Friedrich Miescher - FMI 01.06.2008 31.05.2012 SNSF Professorships

Mechanism and physiological significance of the rapid microRNA catabolism in retinal and non-retinal neurons
Filipowicz Witold Institute Friedrich Miescher - FMI 01.04.2010 31.03.2012 Project funding (Div. I-III)

Polycomb and stem cell identity in vitro and in vivo
Peters Antoine Hendrik Felix Marie Institute Friedrich Miescher - FMI 01.11.2010 28.02.2015 NRP 63 Stem cells and regenerative medicine

Understanding the Genome: the Gasser group workshop
Taddei Angela Institute Friedrich Miescher - FMI 01.11.2005 30.04.2006 Scientific Conferences

Linking retinal and cortical visual processing
Roska Botond Institute Friedrich Miescher - FMI 01.10.2015 30.09.2018 Project funding (Div. I-III)

Elementary computational functions of inhibitory neuronal circuits
Friedrich Rainer Institute Friedrich Miescher - FMI 01.10.2011 30.09.2014 Project funding (Div. I-III)

Understanding molecular mechanisms underlying chromatin reprogramming during male germ cell development
Peters Antoine Hendrik Felix Marie Institute Friedrich Miescher - FMI 01.04.2017 31.03.2021 Project funding (Div. I-III)

Amygdala circuit mechanisms of goal-directed behavior
Courtin Julien Institute Friedrich Miescher - FMI 01.01.2019 31.12.2021 Ambizione

Mechanotransduction and extracellular matrix regulation in fibroblasts
Chiquet Matthias University of Berne - BE 01.04.2005 31.03.2008 Project funding (Div. I-III)

Controlling fear: function and plasticity of inhibitory circuits in the amygdala
Lüthi Andreas Institute Friedrich Miescher - FMI 01.10.2007 30.09.2010 Project funding (Div. I-III)

Workshop "Formation and Plasticity of Neuronal Circuits"
Monard Denis Institute Friedrich Miescher - FMI 01.10.1997 31.12.1997 NRP 38 Diseases of the Nervous System

Investigating the in vivo roles of mammalian NDR kinases in development and colon cancer
Hemmings Brian Institute Friedrich Miescher - FMI 01.12.2011 28.02.2015 Project funding (Div. I-III)

The cell biology of neuronal plasticity: "looking backwards to see forwards"
Verkuyl J. Martin Institute Friedrich Miescher - FMI 01.04.2007 30.09.2007 Scientific Conferences

Regulation of totipotency during animal development
Ciosk Rafal Institute Friedrich Miescher - FMI 01.09.2014 31.08.2017 Project funding (Div. I-III)

Mechanisms of microRNA biogenesis and turnover
Grosshans Helge Institute Friedrich Miescher - FMI 01.02.2010 31.01.2013 Project funding (Div. I-III)

Mapping repair-relevant domains of the nuclear envelope by superresolution microscopy
Gasser Susan Institute Friedrich Miescher - FMI 01.08.2012 31.03.2016 Sinergia

Recognition and Fusion Processes
Burger Max M. Institute Friedrich Miescher - FMI 01.10.1982 31.03.1986 Project funding (Div. I-III)

Study of paternal transmission of epigenetic information
Hisano Mizue Institute Friedrich Miescher - FMI 01.08.2007 31.07.2008 International short research visits

Cell and Developmental Systems -Arolla Conference 2015
Gasser Susan Institute Friedrich Miescher - FMI 01.07.2015 30.09.2015 Scientific Conferences

Plasticity and dynamics of predictive signals in mouse visual cortex
Keller Georg Institute Friedrich Miescher - FMI 01.02.2015 31.01.2020 Temporary Backup Schemes

Dis-inhibitory amygdala circuits in fear conditioning and extinction
Lüthi Andreas Institute Friedrich Miescher - FMI 01.10.2013 30.09.2016 Project funding (Div. I-III)

Mechanisms and Developmental Functions of MicroRNA Turnover: The Exoribonuclease XRN2
Grosshans Helge Institute Friedrich Miescher - FMI 01.02.2013 30.09.2016 Project funding (Div. I-III)

From extracellular matrix to cytoskeleton to nucleus: role of direct physical links in gene regulation by mechanical signals
Chiquet-Ehrismann Ruth Institute Friedrich Miescher - FMI 01.04.2008 31.03.2011 Project funding (Div. I-III)

Regulatory function of microRNAs in mouse retinal neurons
Krol Jacek Institute Friedrich Miescher - FMI 01.01.2012 31.12.2014 Ambizione

Spatiotemporal regulation of stress-dependent translation
Chao Jeffrey Institute Friedrich Miescher - FMI 01.10.2018 30.09.2022 Project funding (Div. I-III)

IX. Congress of the International Society of Developmental Biologists
Burger Max M. Institute Friedrich Miescher - FMI 01.08.1981 31.03.1982 Scientific Conferences

Structural Plasticity in the Hippocampus
Caroni Pico Institute Friedrich Miescher - FMI 01.09.2012 31.08.2015 Project funding (Div. I-III)

Genetic and epigenetic regulation of mammalian CpG islands
Schübeler Dirk Institute Friedrich Miescher - FMI 01.01.2015 31.12.2017 Project funding (Div. I-III)

Lipid metabolism in intestinal organoid formation
Xavier da Silveira dos Santos Aline Institute Friedrich Miescher - FMI 01.03.2017 28.02.2019 Marie Heim-Voegtlin grants

Improvement of potato resistance to late blight disease caused by Phytophtora infestans
Beffa Roland Institute Friedrich Miescher - FMI 01.07.1994 31.03.1997 Swiss Priority Programmes (SPPs)

Role of the bone marrow niche in breat cancer metastasis and therapy response
Hynes Nancy E. Institute Friedrich Miescher - FMI 01.01.2014 31.12.2015 Project funding (Div. I-III)

Long-range Chromatin Organization and Genome Stability
Gasser Susan Institute Friedrich Miescher - FMI 01.01.2012 31.12.2014 Project funding (Div. I-III)

Functional significance and evolutionary conservation of HP1 - RNA interactions
Bühler Marc Institute Friedrich Miescher - FMI 01.01.2015 31.12.2017 Project funding (Div. I-III)

Epigenetic and transcriptional regulation of barrelette map formation
Rijli Filippo Institute Friedrich Miescher - FMI 01.08.2018 31.07.2022 Project funding (Div. I-III)

Studies on Memo: a novel protein with a role in cancer and aging
Hynes Nancy E. Institute Friedrich Miescher - FMI 01.01.2012 30.04.2014 Project funding (Div. I-III)

Strategic Networks in Plant Biology
Hohn Thomas Institute Friedrich Miescher - FMI 01.09.2002 28.02.2003 Scientific Conferences

Bottom-up and top-down neuronal computations in olfaction
Friedrich Rainer Institute Friedrich Miescher - FMI 01.04.2018 31.03.2022 Project funding (Div. I-III)

Mechanisms involved in (early) Pregnancy-Induced Protection against Breast Cancer
Meier-Abt Fabienne Institute Friedrich Miescher - FMI 01.10.2009 31.03.2013 MD-PhD fellowships (funded by SNSF)

Molecular mechanisms regulating the protein sorting in the endo- somal/lysosomal system and the TGN
Rohrer Jack Institute Friedrich Miescher - FMI 01.04.2002 31.03.2005 Project funding (Div. I-III)

The role of LSM proteins in heterochromatic gene silencing
Mattout Anna Institute Friedrich Miescher - FMI 01.10.2016 31.03.2017 Marie Heim-Voegtlin grants

Telomeres and genome stability
Shore David M. Institute Friedrich Miescher - FMI 01.08.2006 31.01.2007 Scientific Conferences

Structural studies of the molecular defence against skin cancer
Thomä Nicolas Institute Friedrich Miescher - FMI 01.12.2008 30.11.2011 Project funding (Div. I-III)

Quantifying gene expression noise via single mRNA imaging in living cells
Voigt Franka Institute Friedrich Miescher - FMI 01.02.2017 31.05.2019 Marie Heim-Voegtlin grants

Dis-inhibitory amygdala circuits in fear conditioning and extinction
Lüthi Andreas Institute Friedrich Miescher - FMI 01.10.2016 30.09.2019 Project funding (Div. I-III)

Studies on the role of RNAi and other RNA turnover mechanisms in initiation and maintenance of heterochromatin
Bühler Marc Institute Friedrich Miescher - FMI 01.06.2012 31.05.2014 SNSF Professorships

DNA methylation and stability of expression in transgenic plants
Hohn Thomas Institute Friedrich Miescher - FMI 01.03.1996 31.08.2000 Swiss Priority Programmes (SPPs)

Biochemistry of Animal Cell Membranes: Biochemistry of Growth Control in Tissue Culture and the Release of Neurotransmitter
Burger Max M. Institute Friedrich Miescher - FMI 01.10.1976 30.09.1979 Project funding (Div. I-III)

Computational functions of inhibitory neuronal circuits
Friedrich Rainer Institute Friedrich Miescher - FMI 01.10.2014 30.09.2017 Project funding (Div. I-III)

Application of intrachromosomal recombination for the mapping of plant chromosomes
Paszkowski Jerzy Institute Friedrich Miescher - FMI 01.10.1991 31.03.1995 Project funding (Div. I-III)

Molecular mechanism underlying Cockayne Syndrome
Scrima Andrea Institute Friedrich Miescher - FMI 01.10.2010 31.12.2012 Ambizione

Switzerland-Japan joint conference on Cell cycle and Genome stability
Shimada Kenji Institute Friedrich Miescher - FMI 01.05.2009 30.06.2009 International Exploratory Workshops

Posttranslational control of synapse formation, organization and stability
Pielage Jan Institute Friedrich Miescher - FMI 01.10.2014 31.03.2018 Project funding (Div. I-III)

Understanding principles of DNA recognition in chromatin
Thomä Nicolas Institute Friedrich Miescher - FMI 01.06.2018 31.05.2022 Project funding (Div. I-III)

The molecular basis of cullin substrate recognition by the COP9 signalosome (CSN)
Thomä Nicolas Institute Friedrich Miescher - FMI 01.10.2012 30.09.2015 Project funding (Div. I-III)
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