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High-End 3D Ultrasound Open Research Platform

English title High-End 3D Ultrasound Open Research Platform
Applicant Thiran Jean-Philippe
Number 170758
Funding scheme R'EQUIP
Research institution Laboratoire de traitement des signaux 5 EPFL - STI - IEL - LTS5
Institution of higher education EPF Lausanne - EPFL
Main discipline Microelectronics. Optoelectronics
Start/End 01.12.2016 - 31.05.2020
Approved amount 350'000.00
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All Disciplines (2)

Discipline
Microelectronics. Optoelectronics
Information Technology

Keywords (9)

compressed sensing; telesonography; FPGA architectures; Ultrasound imaging; aberration correction; optoacoustic imaging; low-power hardware; computed ultrasound tomography; 3D realtime imaging

Lay Summary (French)

Lead
Ce projet R'Equip permettra l'acquisition d'une plateforme d'imagerie ultrason 3D de recherche, permettant de contrôler chaque canal d'une sonde matricielle à 1024 éléments indépendamment et d'accéder aux données brutes capturées par une telle sonde.
Lay summary
L'imagerie ultrason (US), également appelée échographie, est une technique de diagnostique parmi les plus couramment utilisées dans la pratique médicale, en raison de sa simplicité et de son caractère non invasif. La technologie médicale en échographie est soutenue par une recherche active en Suisse, avec des laboratoires importants, à la pointe de la recherche dans la conception de matériel, dans le traitement d'images ainsi que dans la recherche clinique.
Au cours de la dernière décennie, les techniques d’imagerie ultrason ont connu de grands développements, axés sur l'élastographie, l'imagerie de contraste avec microbulles et l'imagerie 3D en temps réel, ainsi que des applications thérapeutiques centrées sur l'ultrason focalisé de haute intensité (HIFU), l'administration ciblée de médicaments et la thrombolyse par ultrasons. Parmi ces développements, l'imagerie 3D est devenue un sujet de recherche majeur. Cette recherche nécessite des équipements appropriés, à savoir des plateformes 3D ouvertes à la recherche, où de nouvelles techniques matérielles et logicielles peuvent être facilement mises en œuvre, testées et validées. C'est le cœur de cette demande R'Equip. Six grands laboratoires du domaine, issus de trois grands instituts suisses de recherche (EPFL, ETHZ et UNIBE), ainsi qu'un hôpital universitaire de référence (CHUV - Lausanne), vont acquérir ensemble une plateforme de recherche 3D ouverte unique en Suisse, qui permettra aux chercheurs de contrôler indépendamment chaque canal d'une sonde matricielle à 1024 éléments et d'accéder aux données brutes élémentaires, fondamentales pour le développement des projets de recherche les plus avancés.
 
Direct link to Lay Summary Last update: 17.01.2017

Responsible applicant and co-applicants

Associated projects

Number Title Start Funding scheme
175974 Regularized Linear Inverse Problems in Diffusion Magnetic Resonance and Ultrasound Imaging 01.11.2017 Project funding (Div. I-III)
144443 Combined deep optoacoustics and ultrasound for quantitative multimodal imaging of the human body 01.01.2013 Project funding (Div. I-III)

Abstract

Ultrasound (US) imaging, also called sonography, is a diagnostic technique among the most commonly used in medical practice, due to its simplicity and non-invasiveness when compared to some of the major alternatives, like X-Ray, Computed Tomography (CT) or Magnetic Resonance Imaging (MRI). Medical US technology is supported by active research in Switzerland, with important laboratories developing leading-edge research in this field, in advanced hardware design, in image processing, as well as in clinical research.Over the last decade, medical US has seen extensive diagnostic developments, focused on elastography, contrast-enhanced imaging with dedicated microbubble contrast agents and real-time 3D imaging, as well as therapeutic applications, centered on high-intensity focused ultrasound (HIFU), targeted drug delivery and ultrasound-mediated thrombolysis. Among these developments, 3D US imaging has been emerging as a major research topic, opening unprecedented perspectives for advanced imaging but also for new therapeutic approaches. To be further developed, this research needs appropriate equipment, namely 3D US platforms open for research, where new hardware and software techniques can be easily implemented, tested and validated. This is the core of this R’Equip request. Six leading researchers in the field, from three major Swiss research institutions (EPFL, ETHZ and UNIBE), together with a leading University Hospital (CHUV - Lausanne), request support for the acquisition a cutting-edge 3D US open research platform. Such a platform, unique in Switzerland, will allow researchers to control each channel of a 1024-element matrix-array probe independently and to access the element raw data, which is fundamental for the development of the most advanced research projects, as illustrated in our research plan.Four projects from the aforementioned Swiss institutions are presented here, each of which will gain tremendous momentum and impact with an access to the requested research platform. The first project, which is part of a big initiative between five laboratories at EPFL, ETHZ and CHUV, will develop software and hardware for a 3D portable device for telesonography that will enable remote diagnostics by clinical experts while the acquisition can be performed by unskilled personnel. The second project will develop US autofocusing techniques through heterogeneous media, that will potentially enable 3D imaging of the brain or HIFU therapy, through the skull, without the need of a craniotomy to provide an acoustic window for the US probe. The third project will develop robust and accurate 3D US computed tomography of speed of sound in order to improve the diagnostic capabilities of US systems. The fourth project will develop efficient clutter reduction techniques for optoacoustic imaging that will potentially improve the diagnostic accuracy in vascular diseases and cancer.All co-PIs are currently involved in major Swiss and European projects in ultrasound imaging, optoacoustics and medical diagnostics. While strengthening and expanding the collaboration between these complementary research groups at the forefront of US research in Switzerland, the acquisition of the requested equipment will provide access to a very unique cutting-edge open US research platform, and empower this group to become a prominent pole of innovation in Europe. Open to other research groups in Switzerland, this equipment and its related projects already sparked the attention and support of several additional Swiss academic, industrial and clinical actors active in the field of US.
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