Project

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A Flow Chemistry Instrumentation

English title A Flow Chemistry Instrumentation
Applicant Renaud Philippe
Number 170727
Funding scheme R'EQUIP
Research institution Departement für Chemie und Biochemie Universität Bern
Institution of higher education University of Berne - BE
Main discipline Organic Chemistry
Start/End 01.12.2016 - 30.11.2017
Approved amount 126'250.00
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All Disciplines (2)

Discipline
Organic Chemistry
Physical Chemistry

Keywords (6)

flow chemistry; photochemistry; CO2 conversion; radical chemistry; organic synthesis; electrochemistry

Lay Summary (French)

Lead
Laboratoire de chimie en flux continu
Lay summary
Le but du projet est d'établir un laboratoire centré sur la chimie en flux continu. Ce nouvel outil technologique ouvre de nouvelles perspectives dans le domaine de la synthèse organique (synthèse de médicaments et de produits naturels par exemple) ainsi que dans le domaine des énergies (conversion du CO2). Le laboratoire de chimie en flux continu permettra notamment de traiter les défis suivants :
- travailler de manière sécurisée avec des intermédiaires hautement réactifs et instables
- développer des conditions réactionnelles facilement reproductibles dans le domaine de la photochimie (chimie initiée par de la lumière) et de l'électrochimie (chimie initiée par des transferts d'électrons).
- faciliter la transition entre la recherche académique et l'utilisation industrielle de nouvelles méthodes de synthèse.
 
Direct link to Lay Summary Last update: 06.04.2017

Responsible applicant and co-applicants

Collaboration

Group / person Country
Types of collaboration
Prof. Ilhyong Ryu / Osaka Japan (Asia)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure
- Exchange of personnel
SCCER Heat and Electricity Storage Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure
- Exchange of personnel
- Industry/business/other use-inspired collaboration
BASF SE Germany (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Industry/business/other use-inspired collaboration
Prof. Siegfried Waldvogel / Uni Mainz Germany (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure
- Exchange of personnel

Associated projects

Number Title Start Funding scheme
172621 Synthetic Methods for Total Synthesis of Natural Products 01.04.2017 Project funding (Div. I-III)
152782 Synthetic Methods for Total Synthesis of Natural Products 01.04.2014 Project funding (Div. I-III)
152346 Radical Mediated Modifications of Natural Products 01.04.2014 SCOPES
172507 CO2 to Value: Electroconversion of CO2 on Electrodeposited Metal Foam Catalysts 01.04.2017 Project funding (Div. I-III)
183296 Benchtop Gas Chromatography-Mass Spectrometry (GC-MS) Instrument for Reaction Monitoring 01.03.2019 R'EQUIP

Abstract

The objective of this project is to set up a laboratory to perform flow chemistry experiments in order to reach a higher level of efficiency in different areas of chemistry involving radical mediated synthesis, heterocyclic chemistry (alkaloids), medicinal chemistry and energy related programs (CO2 conversion). The project does not only aim at introducing a new technology but it will also take advantage of this enabling technology to perform reactions that are problematic in classical batch chemistry such as reaction involving unstable reagents, intermediates and products as well as photochemical and electrochemical transformations. The challenging (photo-)electrochemical conversion of CO2 into products of higher value (e.g. methanol; ethanol; ethylene) will also be investigated. The product distribution of CO2 electro-conversion on metal foam catalysts will be tuned by a flow-cell approach.
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