Galiñanes Gregorio Luis, Bonardi Claudia, Huber Daniel (2018), Directional Reaching for Water as a Cortex-Dependent Behavioral Framework for Mice, in Cell Reports
, 22(10), 2767-2783.
Yüzgeç Ozge, Prsa Mario, Zimmermann Robert, Huber Daniel (2018), Pupil Size Coupling to Cortical States Protects the Stability of Deep Sleep via Parasympathetic Modulation, in Current Biology
, 28(3), 392-400.
Prsa Mario, Galinanes Gregorio, Huber Daniel (2017), Rapid Integration of Artificial Sensory Feedback during Operant Conditioning of Motor Cortex Neurons, in Neuron
, 93(4), 929-939.
Morandell Karin, Huber Daniel (2017), The role of forelimb motor cortex areas in goal directed action in mice, in Scientific Reports
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The main goal of this two year extension is to complement and complete the initially proposed research plan and finalize the doctoral theses of the involved PhD students. We will continue our efforts to gain a better understanding of the network dynamics underlying motor control and skill learning, by using in vivo two-photon imaging in the mouse frontal cortex in combination with quantitative behavioral testing. The mapping of activity over large regions, but with single-cell resolution, will allow us to test the hypothesis that specific movements are represented by broad, intermingled and flexible networks whose rapid rearrangement underlie the learning of novel motor skills. These experiments in rodents will ultimately help us to understand some of the basic neuronal mechanisms that govern our own actions, enabling us to solve new challenges.