Project

Back to overview

Relative contributions of experience-dependent plasticity and of ‘innate’ influences on the brain and cognition

English title Relative contributions of experience-dependent plasticity and of ‘innate’ influences on the brain and cognition
Applicant Golestani Narly
Number 163756
Funding scheme SNSF Professorships
Research institution Clinique de Neurologie Hôpitaux Universitaires de Genève
Institution of higher education University of Geneva - GE
Main discipline Neurophysiology and Brain Research
Start/End 01.04.2016 - 31.08.2019
Approved amount 785'249.00
Show all

All Disciplines (2)

Discipline
Neurophysiology and Brain Research
Other languages and literature

Keywords (15)

functional magnetic resonance imaging; predisposition; genetics; cortical folding; diffusion tensor imaging; expertise; audition; structural magnetic resonance imaging ; language; brain plasticity; dyslexia; computational morphology; computational modelling; bilingualism; simultaneous interpretation

Lay Summary (Italian)

Lead
Le cerveau humain réussit à traiter des informations complexes langagières. Cependant, il reste à mieux comprendre 1) la contribution de l’innée et de l’acquis par rapport aux différences interindividuels dans les aptitudes linguistiques, et 2) la fonction et la structure du cerveau à différents niveaux de traitement linguistique, et comment ceux-ci changent suite à l’acquisition d’une expertise et lors de désordres tel la dyslexie.
Lay summary

Différentes méthodes d’imagerie cérébrale seront utilisés pour mieux comprendre les bases fonctionnelles et structurelles de traitement linguistique, allant de la phonétique jusqu’aux fonctions attentionnels et exécutifs, importants pour le bilinguisme et pour l’interprétation simultanée. Le projet visera à utiliser différentes méthodes avancés d’analyse d’images ainsi que des méthodes comportementaux pour comprendre 1) les mécanismes du traitement des sons de la parole dans le cortex auditif, et comment ceux-ci sont changés dans la dyslexie, 2) des aspects fins de l’anatomie du cortex auditif, et comment ceux-ci sont reliés à des capacités linguistique ainsi que comment ils sont changés dans la dyslexie, 3) des contributions génétiques aux différences interindividuels dans le traitement phonétique et dans l’anatomie du cerveau, 4) comment le cortex auditif change suite à une nouvelle intervention dans le cadre de la dyslexie, 5) comment le cerveau change suite à l’apprentissage de plusieurs langues, et à l’acquisition de l’expertise dans le control du langage chez les interprètes simultanées.   Ces recherches permettront de mieux comprendre la fonction et la structure du cerveau à différents niveaux de traitement linguistique, ainsi que comment ceci change suite à un apprentissage assidu et lors de désordres langagières.

Direct link to Lay Summary Last update: 11.02.2016

Responsible applicant and co-applicants

Employees

Publications

Publication
Cortical encoding of speech enhances task-relevant acoustic information
Rutten Sanne, Santoro Roberta, Hervais-Adelman Alexis, Formisano Elia, Golestani Narly (2019), Cortical encoding of speech enhances task-relevant acoustic information, in Nature Human Behaviour, 3(9), 974-987.
Morpho-syntactic complexity modulates brain activation in Persian-English bilinguals: An fMRI study
Momenian Mohammad, Nilipour Reza, Samar Reza Ghafar, Cappa Stefano F., Golestani Narly (2018), Morpho-syntactic complexity modulates brain activation in Persian-English bilinguals: An fMRI study, in Brain and Language, 185, 9-18.
Beyond bilingualism: multilingual experience correlates with caudate volume
Hervais-Adelman Alexis, Egorova Natalia, Golestani Narly (2018), Beyond bilingualism: multilingual experience correlates with caudate volume, in Brain Structure and Function, 223(7), 3495-3502.
Statistical Learning of Speech Sounds in Dyslexic and Typical Reading Children
Vandermosten Maaike, Wouters Jan, Ghesquière Pol, Golestani Narly (2018), Statistical Learning of Speech Sounds in Dyslexic and Typical Reading Children, in Scientific Studies of Reading, 23(1), 116-127.
Commentary: Broca Pars Triangularis Constitutes a “Hub” of the Language-Control Network during Simultaneous Language Translation
Hervais-Adelman Alexis, Moser-Mercer Barbara, Golestani Narly (2018), Commentary: Broca Pars Triangularis Constitutes a “Hub” of the Language-Control Network during Simultaneous Language Translation, Frontiers in Human Neuroscience, Switzerland.
Brain structural imaging of receptive speech and beyond: a review of current methods
Marie Damien, Golestani Narly (2017), Brain structural imaging of receptive speech and beyond: a review of current methods, in Language, Cognition and Neuroscience, 32(7), 870-890.
Cortical thickness increases after simultaneous interpretation training
Hervais-Adelman Alexis, Moser-Mercer Barbara, Murray Micah, Golestani. Narly (2017), Cortical thickness increases after simultaneous interpretation training, in Neuropsychologia, 98, 212-219.
How and When Does the Second Language Influence the Production of Native Speech Sounds: A Literature ReviewL2 Influences on L1: A Literature Review
Kartushina Natalia, Frauenfelder Ulrich H., Golestani Narly (2016), How and When Does the Second Language Influence the Production of Native Speech Sounds: A Literature ReviewL2 Influences on L1: A Literature Review, in Language Learning, 66(S2), 155-186.
Plasticity of white matter connectivity in phonetics experts
Vandermosten Maaike, Price Cathy J., Golestani Narly (2016), Plasticity of white matter connectivity in phonetics experts, in Brain Structure and Function, 221(7), 3825-3833.
Mutual influences between native and non-native vowels in production: Evidence from short-term visual articulatory feedback training
Kartushina Natalia, Hervais-Adelman Alexis, Frauenfelder Ulrich Hans, Golestani Narly (2016), Mutual influences between native and non-native vowels in production: Evidence from short-term visual articulatory feedback training, in Journal of Phonetics, 57, 21-39.

Collaboration

Group / person Country
Types of collaboration
Elia Formisano/Maastricht University Netherlands (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Exchange of personnel
Rotman Research Institute/ Hospital for Sick Children Research Institute/University of Toronto Canada (North America)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Faculty of Psychology and of Education Sciences/University of Geneva Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Wellcome Trust Centre for Neuroimaging, University College London (UCL), London, UK Great Britain and Northern Ireland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Diagnostische und interventionelle Neuroradiologie Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Dept of Neuroradiology/ Heidelberg Medical School Germany (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Sophie Bouton / Laboratoire Dynamique du Langage Université Lyon 2 France (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Medical Image Processing Lab/University of Geneva Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Cognitive Neuroscience group / Faculty of Psychology and Education Sciences Unige Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Anne-Lise Giraud / University of Geneva Switzerland (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
Parenting and Special Education/Katholieke Universteit Leuven Belgium (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Exchange of personnel

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
Closing colloquium of the Language and Communication thematic network Talk given at a conference Characterizing Heschl’s gyrus shape by a Multivariate Concavity Amplitude Index 03.09.2019 Geneva, Switzerland Golestani Narly; Dalboni da Rocha Josue Luiz;
Closing colloquium of the Language and Communication thematic network Poster Brain structural correlates of dyslexia 03.09.2019 Geneva, Switzerland Rutten Sanne; Golestani Narly; Marie Damien;
Closing colloquium of the Language and Communication thematic network Talk given at a conference Cortical encoding of speech enhances task-relevant acoustic information 03.09.2019 Geneva, Switzerland Rutten Sanne; Golestani Narly;
Organisation of Human Brain Mapping Meeting 2019 Poster Multivariate Concavity Amplitude Index (MCAI) for characterizing Heschl’s gyrus shape 09.06.2019 Rome, Italy Golestani Narly; Dalboni da Rocha Josue Luiz;
2019 Annual Meeting of the SSN Poster Multivariate Concavity Amplitude Index (MCAI) for characterizing Heschl’s gyrus shap 01.02.2019 Geneva, Switzerland Golestani Narly; Dalboni da Rocha Josue Luiz;
Alpine Brain Meeting 2019 Poster Multivariate Concavity Amplitude Index (MCAI) for characterizing Heschl’s gyrus shap 06.01.2019 Champéry, Switzerland Golestani Narly; Dalboni da Rocha Josue Luiz;
Alpine Brain Meeting 2018 Talk given at a conference Contextual effects on the neural encoding of speech in the auditory cortex 11.01.2018 Champery, Switzerland Golestani Narly; Rutten Sanne;
Alpine brain meeting 2018 Poster Auditory cortex myelination abnormalities in dyslexia and relationships with reading performance 07.01.2018 Champery, Switzerland Golestani Narly; Marie Damien; Rutten Sanne;
Alpine brain meeting 2018 Poster TASH: Toolbox for the automated segmentation of Heschl’s gyrus: Applications to musicians, language learning and multilingualism 07.01.2018 Champery, Switzerland Golestani Narly; Dalboni da Rocha Josue Luiz;
International Conference on Auditory Cortex Talk given at a conference Contextual effects on the neural encoding of speech sounds 10.09.2017 Banff, Canada Rutten Sanne; Golestani Narly;
Organisation of Human Brain Mapping Meeting Poster Multilingualism and subcortical plasticity – beyond bilingualism 25.06.2017 Vancouver, Canada Golestani Narly;
Organisation of Human Brain Mapping Meeting Poster Relationships between dyslexia, gyrification of Heschl’s gyrus and reading performance 25.06.2017 Vancouver, Canada Golestani Narly; Marie Damien;
Invited speaker for inauguration of the Institute for Language, Communication and the Brain Talk given at a conference Neural bases of language learning and expertise 09.06.2017 Marseilles, France Golestani Narly;
Swiss society for Neuroscience annual meeting Poster New method for automatic surface-based segmentation of Heschl’s gyrus 27.01.2017 Basel, Switzerland Golestani Narly; Dalboni da Rocha Josue Luiz;
Swiss Society for Neuroscience annual meeting Poster Relationships between dyslexia, gyrification of Heschl’s gyrus and reading performance 27.01.2017 Basel, Switzerland Golestani Narly;
Alpine brain meeting 2017 Poster New method for automatic surface-based segmentation of Heschl’s gyrus 08.01.2017 Champery, Switzerland Dalboni da Rocha Josue Luiz; Golestani Narly;
Alpine brain meeting 2017 Poster Relationships between dyslexia, gyrification of Heschl’s gyrus and reading performance 08.01.2017 Champery , Switzerland Golestani Narly;
European Society for Translation Talk given at a conference Neuroscientific investigations of Simultaneous Interpreting: Results and Perspectives 15.09.2016 Aarhus, Denmark Golestani Narly;
Conference on Multilingualism (COM) 2016 Talk given at a conference Neural bases of language learning and expertise 11.09.2016 Ghent, Belgium Golestani Narly;
Society for the Neurobiology of Language 2016 Annual Meeting Poster Beyond bilingualism - Multilingual language experience correlates with bilateral caudate volume in polyglots 17.08.2016 London, Great Britain and Northern Ireland Golestani Narly;
Annual Meeting of the Organization for Human Brain Mapping Poster Contextual effects on the neural encoding of speech sounds 26.06.2016 Geneva, Switzerland Rutten Sanne; Golestani Narly;
Annual Meeting of the Organization for Human Brain Mapping Poster Brain structural correlates of multilingualism 26.06.2016 Geneva, Switzerland Golestani Narly;
Annual Meeting of the Organization for Human Brain Mapping Poster Simultaneous Interpreting Training Induces Changes In Brain Structural Connectivity 26.06.2016 Geneva, Switzerland Golestani Narly;
Organisation of Human Brain Mapping Meeting Poster New method for automatic surface-based segmentation of Heschl’s gyrus 25.06.2016 Vancouver, Canada Dalboni da Rocha Josue Luiz; Golestani Narly;
8th International Symposium on Second Language Speech-New Sounds Talk given at a conference How and why learning to produce non-native sounds affects native production 09.06.2016 Aarhus, Denmark Golestani Narly;


Knowledge transfer events

Active participation

Title Type of contribution Date Place Persons involved
Ronde table discussion on Langage and Communication sciences Performances, exhibitions (e.g. for education institutions) 04.09.2019 Geneba, Switzerland Golestani Narly;


Communication with the public

Communication Title Media Place Year
Media relations: print media, online media Des chants d'oiseaux implantés artificiellement dans leur mémoire Heidi News Western Switzerland 2019
Media relations: print media, online media how the brain distinguishes between voice and sound Unige Press release International 2019
Media relations: print media, online media Le plus tôt, c’est le mieux 24 heures Western Switzerland 2019
Talks/events/exhibitions Semaine du Cerveau 2018 Western Switzerland 2018
Media relations: radio, television Apprentissage des langues: de nouvelles approches RTS TV Western Switzerland 2017
Media relations: print media, online media Hoe werkt het brein van simultaantolken? online media Netherlands International 2017
Media relations: radio, television Rencontre avec Narly Golestani RTS / CQFD Western Switzerland 2016

Associated projects

Number Title Start Funding scheme
133701 Relative contributions of experience-dependent plasticity and of ‘innate’ influences on the brain and cognition 01.04.2012 SNSF Professorships
122085 Experience-dependant brain structural and functional plasticity in simultaneous language interpreters 01.11.2008 Project funding (Div. I-III)

Abstract

This SNSF extension has as research objectives to elucidate the relative contributions of nature versus nurture with respect to the brain and language in humans, using non-invasive brain imaging methods. Our studies span different levels of language processing, ranging from low-level, auditory processing to higher-level, linguistic processing, to studies on multilingualism, and finally, to processes beyond language per se such as the cognitive and executive control mechanisms required to manage multilingualism. The research agenda will include a) a detailed exploration of auditory cortex function and dysfunction using novel computational modelling methods; b) the development of a novel computational morphometry approach to quantify the shape and size of the auditory cortex, and application of this method to different existing data-sets in populations previously shown to display auditory cortex alterations; c) investigation of molecular genetic influences on auditory cortex morphology and on related measures of domain-specific aptitude; d) longitudinal behavioural testing and functional brain imaging of dyslexia, in particular in relation to novel intervention approaches; and d) investigation of brain structural correlates of speaking two or more languages, and investigation of brain functional and structural correlates of executive skill in simultaneous interpreters. These studies will a) pave the way for explanatory models of auditory brain response and of higher-level, top-down influences on that response, b) allow to tease apart the relative influences of nature and of nurture on auditory cortex features and on related domain-specific aptitudes, c) allow to develop explanatory models of auditory cortex functional alterations in dyslexia, and possibly lead to new intervention for this disorder, and d) advance our understanding of the neural adaptations that accompany the heightened executive skills in interpreters and in multilingual individuals, skills which have previously been shown to confer protective effects in diseases such as dementia.
-