evolution; genetics; salmonids; fish; variance components; experimental breeding; genetic quality; sexual selection; ecology; supportive breeding
Wedekind Claus (2017), Demographic and genetic consequences of disturbed sex determination, in Philosophical Transactions of the Royal Society B
, 372, 20160326.
Wilkins L.G.E., Marques da Cunha L., Glauser G., Vallat A., Wedekind C. (2017), Environmental stress linked to consumption of maternally derived carotenoids in brown trout embryos (Salmo trutta), in Ecology and Evolution
, 7, 5082-5093.
Wilkins Laetitia G. E., Marques da Cunha Lucas, Menin Laure, Ortiz Daniel, Vocat-Mottier Véronique, Hobil Matay, Nusbaumer David, Wedekind Claus (2017), Maternal allocation of carotenoids increases tolerance to bacterial infection in brown trout, in Oecologia
von Siebenthal B. A., Pompini M., Müller R., Wedekind C. (2017), Pros and cons of fluorescent pigment mass marking with different colours: A 5-year long study on grayling (Thymallus thymallus L.), in Fisheries Management and Ecology
, 24(2), 173-175.
Maitre Diane, Selmoni Oliver M., Uppal Anshu, Marques da Cunha Lucas, Wilkins Laetitia G. E., Roux Julien, Mobley Kenyon B., Knörr Susanne, Robinson-Rechavi Marc, Wedekind Claus (2017), Sex Differentiation In Grayling (Salmonidae) Goes Through An All-Male Stage And Is Delayed In Genetic Males Who Instead Grow Faster, in bioRxiv
Selmoni Oliver M., Maitre Diane, Roux Julien, Wilkins Laetitia G. E., Marques da Cunha Lucas, Vermeirssen Etienne, Knörr Susanne, Robinson-Rechavi Marc, Wedekind Claus (2017), Sex-Specific Changes In Gene Expression And Delayed Sex Differentiation In Response To Estrogen Pollution In Grayling (Salmonidae), in bioRxiv
Wilkins Laetitia G. E., Fumagalli Luca, Wedekind Claus (2016), Effects of host genetics and environment on egg-associated microbiotas in brown trout (Salmo trutta)., in journal-article
, 25(19), 4930-4945.
Clark E.S., Pompini M., Uppal A., Wedekind C. (2016), Genetic correlations and little genetic variance for reaction norms may limit potential for adaptation to pollution by ionic and nanoparticulate silver in a whitefish (Salmonidae), in Ecology and Evolution
, 6(9), 2751-2762.
Wilkins L.G.E., Rogivue A., Fumagalli L., Wedekind C. (2015), Declining diversity of egg-associated bacteria during development of naturally spawned whitefish embryos (Coregonus spp.), in Aquatic Sciences
, 77(3), 481-497.
Wilkins Laetitia G. E., Clark Emily S., Farinelli L., Wedekind Claus, Fumagalli Luca (2015), Embryonic gene expression of Coregonus palaea (whitefish) under pathogen stress as analyzed by high-throughput RNA-sequencing., in journal-article
, 47(1), 130-140.
Wilkins Laetitia G. E., Rogivue Aude, Schütz Frédérik, Fumagalli Luca, Wedekind Claus (2015), Increased diversity of egg-associated bacteria on brown trout (Salmo trutta) at elevated temperatures., in journal-article
, 5, 17084.
Natural populations of fish often display significant variation not only in parental strategies but also in potential indicators of ‘genetic quality’ (i.e. high breeding value for total fitness), as concluded from correlations between the expression of male sexual ornaments and the viability of their offspring. Such genetic correlations have been found in several fishes, including some with non-resource based mating systems. Variation in genetic quality is likely to play an important role in evolution, but the current understanding of within-population variation of fitness-related traits is still insufficient. We will work on this problem with natural populations of brown trout (Salmo trutta) and grayling (Thymallus thymallus). These fish are excellent models because individuals produce large number of gametes, fertilization is external, and there is no parental care. Therefore, differential investment as typically found in internal fertilizers cannot confound estimates of genetic effects. Nested half-sib breeding designs based on in vitro fertilizations and a high level of replication enable us to estimate the variance components (i.e. the additive and non-additive genetic variance and the maternal environmental effects) for various traits that can be studied in much detail in the laboratory, including growth and survival after exposure to pathogens or pollutants. We plan to closely link such laboratory experiments with large-scale field studies to better understand the variance components of fitness-related traits in natural environ¬ments and at different life-history stages. Because migration can be important in our study species, our field study will involve a large number of streamlets and streams within a well-defined stream network. We have recently finished a 4-year long research collaboration with the Fishery Inspectorate of the Bern canton (Switzerland) on the demography and population genetics of brown trout and grayling within this study area. The Bern canton has now offered us full access to their ongoing supplementary breeding program for brown trout and grayling, i.e. they have granted us the control over the production of all fish that will be released into the streamlets and streams of the study area. With a few measures, we will turn their routine into a large-scale experiment: all fish that are to be released into the wild will be produced experimentally in a block-wise full-factorial breeding design to produce half-sib groups of known strengths. Genotyping of all parents and of samples of offspring caught from the wild at different times and locations will be used to reconstruct the half-sib families. The performance of these brown trout and grayling in the wild shall be compared (i) to different types of parallel and laboratory-based stress tests on samples of each half-sib group, and (ii) to characteristics of their parents, including sexual ornaments, growth rate, life-history strategy, and mutational load as determined via gynogenesis on egg samples. The resulting variance components of important fitness traits such as growth, survival, timing of life-history events (including migration and maturation), or resistance to pathogens and pollutants, and the improved estimates of genetic correlations (e.g. to sexual ornaments) as determined under laboratory and field conditions, will help us to better understand processes that are central for evolutionary biology and conservation, including, for example, adaptation to anthropogenic changes, or the significance of mate choice and of different reproductive systems for the mean viability within natural populations.