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Sexually antagonistic selection: a role for the melanocortin system

Titel Englisch Sexually antagonistic selection: a role for the melanocortin system
Gesuchsteller/in Roulin Alexandre
Nummer 153467
Förderungsinstrument Projektförderung (Abt. I-III)
Forschungseinrichtung Département d'Ecologie et d'Evolution Faculté de Biologie et de Médecine Université de Lausanne
Hochschule Universität Lausanne - LA
Hauptdisziplin Oekologie
Beginn/Ende 01.07.2014 - 30.06.2017
Bewilligter Betrag 700'000.00
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Alle Disziplinen (2)

Disziplin
Oekologie
Zoologie

Keywords (5)

Melanin; Melanin-based color; Melanocortin; Color polymorphism; Sexually antagonistic selection

Lay Summary (Französisch)

Lead
Etudier l’importance du système des mélanocortines afin d’expliquer pourquoi chez les vertébrés les colorations mélaniques sont si souvent associées à d’autres traits physiologiques et comportementaux.
Lay summary

Etablir le lien entre phénotype et génotype est clé pour comprendre l’évolution, la maintenance et la fonction adaptative des variations phénotypiques entre individus. C’est tout particulièrement vrai pour les phénotypes qui sont sélectionnés positivement chez un sexe et négativement chez l’autre. Dans ce contexte, identifier les gènes responsables de la variation phénotypique est intéressant car ces gènes ont des effets bénéfiques chez un sexe mais néfastes chez l’autre. Pour étudier cette question, nous considérons la chouette effraie, une espèce cosmopolite dont les colorations du plumage varie énormément entre individus. Nous avons déjà montré que les femelles mélaniques ont un avantage sélectif tandis que les mâles mélaniques sont contre-sélectionnés. Notre but maintenant est de démontrer que ces effets sont dus au fait que le mélanisme est déterminé par les gènes du système des mélanocortines. Ces gènes sont impliqués dans la mélanogenèse et ont également des effets pléiotropes sur un grand nombre de traits physiologiques et comportementaux. Par ailleurs, ils sont connus pour être impliqués dans plusieurs maladies humaines. Etant donné que le système des mélanocortines est très conservé chez les vertébrés, des études menées en conditions naturelles chez des organismes sauvages peuvent apporter un éclairage nouveau sur des problématiques aussi diverses que la biologie évolutive ou des problèmes biomédicaux. 


Direktlink auf Lay Summary Letzte Aktualisierung: 08.04.2014

Verantw. Gesuchsteller/in und weitere Gesuchstellende

Mitarbeitende

Publikationen

Publikation
« Nature knows no boundaries »: the role of nature conservation in peacebuilding
Roulin Alexandre, Mansour Abu Rashid, Baruch Spiegel, Dreiss Amélie, Leshem Yossi (2017), « Nature knows no boundaries »: the role of nature conservation in peacebuilding, in Trends in Ecology and Evolution , 32, 305-310.
Genomics of colouration in natural animal populations
San Jose Garcia Luis, Roulin Alexandre (2017), Genomics of colouration in natural animal populations, in Philosophical Transaction of the Royal Society of London , B 372, 20160337.
MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration
Luis San Jose Garcia, Ducrest Anne-Lyse, Ducret Valérie, Simon Céline, Richter Hannes, Wakamatsu Kazu, Roulin Alexandre (2017), MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration, in Molecular Ecology , 26, 259-276.
The effect of food quality during growth on spatial memory consolidation in adult pigeons
Scriba Madeleine, Gasparini Julien, Jacquin Lise, Mettke-Hofmann NC, Rattenborg Niels, Roulin Alexandre (2017), The effect of food quality during growth on spatial memory consolidation in adult pigeons, in Journal of Experimental Biology , 220, 573-581.
Barn owl feathers as biomonitors of mercury : sources of variation in sampling procedures
Roque Ines, Lourenço Rui, Marques Ana, Coelho Joao Pedro, Coelho Claudia, Pereira Eduarda, Rabaça Joao, Roulin Alexandre (2016), Barn owl feathers as biomonitors of mercury : sources of variation in sampling procedures, in Ecotoxicology , 25, 469-480.
Barn owls display larger black feather spots in cooler regions on the British Isles
Roulin Alexandre, Randin Christophe (2016), Barn owls display larger black feather spots in cooler regions on the British Isles, in Biological Journal of the Linnean Society , 119, 445-454.
Condition-dependence, pleiotropy and the handicap principle of sexual selection in melanin-based colouration
Roulin Alexandre (2016), Condition-dependence, pleiotropy and the handicap principle of sexual selection in melanin-based colouration, in Biological Reviews , 91, 328-348.
Demographic routes to variability and regulation in bird populations
Sæther Berndt-Erik, Grøtan Vidar, Engen Steinar, Coulson Tim, Grant Peter, Visser Marcel, Brommer Jon, Grant Rosemary, Gustafsson Lars, Hatchwell Ben, Jerstad Kurt, Karell Patrick, Pietiäinen Hannu, Roulin Alexandre, Rostad Ole, Weimerskirch Henri (2016), Demographic routes to variability and regulation in bird populations, in Nature Communication, 7, 12001.
Double brooding and offspring desertion in the barn owl (Tyto alba)
Béziers Paul, Roulin Alexandre (2016), Double brooding and offspring desertion in the barn owl (Tyto alba), in Journal of Avian Biology, 47, 235-244.
Evolutionary trade-off between naturally and sexually selected melanin-based colour traits in the worldwide distributed barn owls and allies
Roulin Alexandre (2016), Evolutionary trade-off between naturally and sexually selected melanin-based colour traits in the worldwide distributed barn owls and allies, in Biological Journal of the Linnean Society , 119, 455-476.
Family-assisted inference of the genetic architecture of MHC variation
Gaigher Arnaud, Burri Reto, Gharib WH, Taberlet Pierre, Roulin Alexandre, Fumagalli Luca (2016), Family-assisted inference of the genetic architecture of MHC variation, in Molecular Ecology Resources , 16, 1353-1364.
Interspecific correlation between red blood cell mitochondrial ROS production, cardiolipin content and longevity in birds
Delhaye Jessica, Salamin Nicolas, Roulin Alexandre, Criscuolo François, Bize Pierre, Christe Philippe (2016), Interspecific correlation between red blood cell mitochondrial ROS production, cardiolipin content and longevity in birds, in Age, 38, 433-443.
Just google it : assessing the use of Google images to describe geographical variation in visible traits of organisms
Leighton Gabrielle, Hugo Pierre, Roulin Alexandre, Amar Arjun (2016), Just google it : assessing the use of Google images to describe geographical variation in visible traits of organisms, in Methods in Ecology and Evolution , 7, 1060-1070.
Lifespan and reproductive cost explain interspecific variation in the optimal onset of reproduction
Mourocq Emeline, Bize Pierre, Roulin Alexandre (2016), Lifespan and reproductive cost explain interspecific variation in the optimal onset of reproduction, in Evolution, 70, 296-313.
Phylogeny, biogeography and diversification of barn owls (Aves, Strigiformes)
Aliabadian Mansour, Alaei-Kakhki Niloofar, Mirshamsi Omid, Nijman Vincent, Roulin Alexandre (2016), Phylogeny, biogeography and diversification of barn owls (Aves, Strigiformes), in Biological Journal of the Linnean Society , 119, 904-918.
Prosody predicts contest outcome in non-verbal dialogs
Dreiss Amélie, Chatelain Philippe, Roulin Alexandre, Richner Heinz (2016), Prosody predicts contest outcome in non-verbal dialogs, in Plos One, 11, e0166953.
Reciprocal preening and food sharing in colour polymorphic nestling barn owls
Roulin Alexandre, des Monstiers Baudouin, Ifrid Estelle, Da Silva Arnaud, Genzoni Estelle, Dreiss Amélie (2016), Reciprocal preening and food sharing in colour polymorphic nestling barn owls, in Journal of Evolutionary Biology , 29, 380-394.
Sex- and melanin-specific variations in the oxidative status of tawny owls in response to manipulated reproductive effort
Emaresi Guillaume, Henry Isabelle, Gonzalez Esther, Roulin Alexandre, Bize Pierre (2016), Sex- and melanin-specific variations in the oxidative status of tawny owls in response to manipulated reproductive effort, in Journal of Experimental Biology , 219, 73-79.
Sex-specific allelic transmission suggests sexual conflict at MC1R
Ducret Valérie, Gahier Arnaud, Simon Céline, Goudet Jérôme, Roulin Alexandre (2016), Sex-specific allelic transmission suggests sexual conflict at MC1R, in Molecular Ecology, 25, 4551-4563.
Shrews and moles are less often captured by European barn owls nowadays than 150 years ago
Roulin Alexandre (2016), Shrews and moles are less often captured by European barn owls nowadays than 150 years ago, in Bird Study, 63, 559-563.
Social huddling and physiological thermoregulation are related to melanism in the nocturnal barn owl
Dreiss Amélie, Robin Séchaud, Béziers Paul, Villain Nicolas, Genoud Michel, Almasi Bettina, Jenni Lukas, Roulin Alexandre (2016), Social huddling and physiological thermoregulation are related to melanism in the nocturnal barn owl, in Oecologia , 180, 371-381.
Solutions for archiving data in long-term studies: a reply to Whitlock et al.
Mills JA, Roulin Alexandre (2016), Solutions for archiving data in long-term studies: a reply to Whitlock et al., in Trends in Ecology and Evolution , 31, 85-87.
Strong decline in the consumption of invertebrates by barn owls from 1860 to 2012 in Europe
Roulin Alexandre (2016), Strong decline in the consumption of invertebrates by barn owls from 1860 to 2012 in Europe, in Bird Study, 63, 146-147.
The genetic basis of color-related local adaptation in a ring-like colonization around the Mediterranean
Burri Reto, Antoniazza Sylvain, Gaigher Arnaud, Ducrest Anne-Lyse, Simon Céline, Fumagalli Luca, Goudet Jérome, Roulin Alexandre (2016), The genetic basis of color-related local adaptation in a ring-like colonization around the Mediterranean, in Evolution , 70, 140-153.
Vocal communication regulates sibling competition over food stock
Dreiss Amélie, Gaime Florence, Delarbre Alice, Moroni Letizia, Lenarth Melissa, Roulin Alexandre (2016), Vocal communication regulates sibling competition over food stock, in Behavioral Ecology and Sociobiology , 70, 927 -937.
A record of communal nesting in the barn owl (Tyto alba)
Hadad Ezra, Roulin Alexandre, Charter Motti (2015), A record of communal nesting in the barn owl (Tyto alba), in The Wilson Journal of Ornithology , 127, 114-119.
Agricultural land-use and human presence around breeding sites increase stress-hormone levels and decrease body mass in barn owl nestlings
Almasi Bettina, Béziers Paul, Roulin Alexandre, Jenni Lukas (2015), Agricultural land-use and human presence around breeding sites increase stress-hormone levels and decrease body mass in barn owl nestlings, in Oecologia , 179, 89-101.
Archiving primary data: solutions for long-term studies
Mills JA, Teplitsky C, Arroyo B, Charmantier A, Becker PH, Birkhead TR, Bize P, Blumstein DT, Bonenfant C, Boutin S, Bushuev A, Cam E, Cockburn A, Côté SD, Coulson JC, Daunt F, Dingemanse NJ, Doligez B, Drummond H, Espie RHM, Festa-Bianchet M, Frentiu F, Fitzpatrick JW, Furness RW, Roulin Alexandre (2015), Archiving primary data: solutions for long-term studies, in Trends in Ecology and Evolution , 30, 581-589.
Effect of the MC1R gene on sexual dimorphism in melanin-based coloration
San-Jose Garcia Luis, Ducrest Anne-Lyse, Ducret Valérie, Béziers Paul, Simon Céline, Wakamatsu Kazu, Roulin Alexandre (2015), Effect of the MC1R gene on sexual dimorphism in melanin-based coloration, in Molecular Ecology , 24, 2794-2808.
Gloger’s rule in North American barn owls
Roulin Alexandre, Randin Christophe (2015), Gloger’s rule in North American barn owls, in Auk, 132, 321-332.
Morph specific variation in innate and acquired immunity supports pleiotropy in the melanocortin system
Gangoso L, Roulin Alexandre, Ducrest Anne-Lyse, Grande Juan Manuel, Figuerola Juan (2015), Morph specific variation in innate and acquired immunity supports pleiotropy in the melanocortin system, in Oecologia , 178, 1113-1123.
Pheomelanin-based colouration is correlated with indices of flying strategies in the barn owl
Charter Motti, Yossi Leshem, Izhaki Ido, Roulin Alexandre (2015), Pheomelanin-based colouration is correlated with indices of flying strategies in the barn owl, in Journal of Ornithology , 156, 309-312.
Relationship between diet and reproductive success in the Israeli barn owl
Charter Motti, Izhaki Ido, Leshem Yossi, Meyrom Kobi, Roulin Alexandre (2015), Relationship between diet and reproductive success in the Israeli barn owl, in Journal of Arid Environments , 122, 59-63.
Sex-linked inheritance, genetic correlations and sexual dimorphism in three melanin-based color traits in the barn owl
Roulin Alexandre, Jensen Henrik (2015), Sex-linked inheritance, genetic correlations and sexual dimorphism in three melanin-based color traits in the barn owl, in Journal of Evolutionary Biology , 28, 655-666.
Signalling value of maternal and paternal melanism in the barn owl : implication for the resolution of the lek paradox
Almasi Bettina, Roulin Alexandre (2015), Signalling value of maternal and paternal melanism in the barn owl : implication for the resolution of the lek paradox, in Biological Journal of the Linnean Society , 115, 376-390.
Social rules govern vocal competition in the barn owl
Dreiss Amélie, Ruppli Charlène, Faller Christof, Roulin Alexandre (2015), Social rules govern vocal competition in the barn owl, in Animal Behaviour , 102, 95-107.
Spatial variation in the decline of European birds as shown by the barn owl (Tyto alba) diet
Roulin Alexandre (2015), Spatial variation in the decline of European birds as shown by the barn owl (Tyto alba) diet, in Bird Study, 62, 271-275.
Information retention during competitive interactions: siblings need to constantly repeat vocal displays
Dreiss Amélie, Ruppli Charlène, Antille Séverine, Roulin Alexandre (2014), Information retention during competitive interactions: siblings need to constantly repeat vocal displays, in Evolutionary Biology , 42, 63-74.
Natural selection in a post-glacial range expansion: the case of the colour cline in the European barn owl
Antoniazza Sylvain, Ricardo K., Neuenschwander Sam, Burri Reto, Gaigher Arnaud, Roulin Alexandre, Goudet Jérome (2014), Natural selection in a post-glacial range expansion: the case of the colour cline in the European barn owl, in Molecular Ecology , 23, 5508-5523.
Conditional association between melanism and personality in Israeli barn owls
Peleg Ori, Charter Motti, Leshem Yossi, Izhaki Ido, Roulin Alexandre, Conditional association between melanism and personality in Israeli barn owls, in Bird Study, 61, 572-577.

Wissenschaftliche Veranstaltungen

Aktiver Beitrag

Titel Art des Beitrags Titel des Artikels oder Beitrages Datum Ort Beteiligte Personen
Invited talk Vortrag im Rahmen einer Tagung The barn owl: a predator that metamorphosesfrom a hawk into a dove 19.05.2017 Evora, Portugal Roulin Alexandre;
Invited talk Vortrag im Rahmen einer Tagung The barn owl: a predator that metamorphoses from a hawk into a dove 09.03.2017 University of Cork, Irland Roulin Alexandre;
Invited talk Vortrag im Rahmen einer Tagung The barn owl: a predator that metamorphoses from a hawk into a dove 17.02.2017 Natural History Museum of Nairobi, Kenia Roulin Alexandre;
Invited talk Vortrag im Rahmen einer Tagung Animal coloration: lessons from owls and lizards 13.12.2016 Dijon, Frankreich San Jose Garcia Luis Martin;
Invited talk Vortrag im Rahmen einer Tagung The barn owl: a predator that metamorphoses from a hawk into a dove 08.10.2016 University of Turku, Finnland Roulin Alexandre;
10th European Ornithologist’s Union Conference, Badajoz Vortrag im Rahmen einer Tagung Melanin-specific female life-history strategies 25.08.2016 Badajoz, Spanien Roulin Alexandre;
Congress of the European Society of Evolutionary Biology Vortrag im Rahmen einer Tagung The adaptive value of melanin-based color: a role for pleiotropy 20.08.2016 Lausanne, Schweiz Roulin Alexandre;
Animal Coloration Workshop at WIKO in Berlin Vortrag im Rahmen einer Tagung Melanin-based coloration 18.05.2016 Berlin, Deutschland Roulin Alexandre;
Invited talk Vortrag im Rahmen einer Tagung The adaptive function of melanin-based color: a role for pleiotropy 07.12.2015 University of Saint-Etienne, Frankreich Roulin Alexandre;
Invited talk Vortrag im Rahmen einer Tagung The adaptive function of melanin-based color: a role for pleiotropy 19.11.2015 Wissenschaftskolleg in Berlin, Deutschland Roulin Alexandre;
Congress of the European Society of Evolutionary Biology Vortrag im Rahmen einer Tagung Effects of MC1R gene on sexual dimorphism in barn owls 20.08.2015 Lausanne, Schweiz San Jose Garcia Luis Martin;
Invited talk Vortrag im Rahmen einer Tagung The adaptive function of melanin-based color: a role for pleiotropy 01.06.2015 University of Cape Town, Südafrika (Republik) Roulin Alexandre;
Tulipe Conference in Toulouse Vortrag im Rahmen einer Tagung The adaptive value of melanin-based color: a role for pleiotropy 27.04.2015 Toulouse, Frankreich Roulin Alexandre;
Invited talk Vortrag im Rahmen einer Tagung The adaptive function of melanin-based color: a role for pleiotropy 05.02.2015 University of Pierre et Marie Curie, Paris, Frankreich Roulin Alexandre;
Invited talk Vortrag im Rahmen einer Tagung The adaptive function of melanin-based color: a role for pleiotropy 21.11.2014 University of Deakin, Australien Roulin Alexandre;
Invited talk Vortrag im Rahmen einer Tagung The adaptive function of melanin-based color: a role for pleiotropy 18.09.2014 University of Bern, Schweiz Roulin Alexandre;
18th Evolutionary Biology Meeting at Marseilles Vortrag im Rahmen einer Tagung The adaptive value of melanin-based color: a role for pleiotropy 16.09.2014 Marseilles, Frankreich Roulin Alexandre;
26th international ornithological congress Vortrag im Rahmen einer Tagung The adaptive value of melanin-based color: a role for pleiotropy 18.08.2014 Tokyo, Japan Roulin Alexandre;
VII European Conference on Behavioural Biology Vortrag im Rahmen einer Tagung Interactions between young siblings: from rivalry to negotiation up to cooperation 18.07.2014 Prague, Tschechische Republik Roulin Alexandre;


Veranstaltungen zum Wissenstransfer

Aktiver Beitrag

Titel Art des Beitrags Titel des Artikels oder Beitrages Datum Ort Beteiligte Personen
8 Talks at Swiss Congresses Lausanne Connaissance 3 l’Université des seniors; Bern SCNAT Académie suisse des Sciences naturelles 2016; Fribourg Société fribourgeoise des sciences naturelles 2016; Aigle Connaissance 3 l’université des seniors 2016; Lausan Vortrag 31.05.2017 Lausanne, Schweiz
On the heritage of the air force & cooperation of the public in the protection of birds Vortrag 14.05.2017 Tel Aviv University, Israel
DLD Conference Munich Vortrag 17.01.2017 Munich, Deutschland
Société romande des Armes Spéciales Vortrag 13.11.2016 Lausanne, Schweiz
Gymnase du Soir à Lausanne Vortrag 03.11.2016 Lausanne, Schweiz
SCNAT Académie suisse des Sciences naturelles Vortrag 22.10.2016 Berne, Schweiz
WSL Birminsdorf Vortrag 24.09.2016 Birminsdorf, Schweiz
Generals’ Forum Israel-Jordan « Nature and environment know no boundaries, The military dimension integrated with environmental, governmental and academic organization » Vortrag 21.09.2016 Netanya, Israel
Journée ERFA 2016 Territoire et environnement DDPS Armée Suisse à Thun Vortrag 15.09.2016 Thun, Schweiz
Embassy of Israel in Bern 2016 Vortrag 12.09.2016 Bern, Schweiz
Faculty of Biology and Medicine of the University of Lausanne Vortrag 28.06.2016 Lausanne, Schweiz
Connaissance 3 l’université des seniors à Aigle Vortrag 19.05.2016 Aigle, Schweiz
WEF Davos Vortrag 22.01.2016 Davos, Schweiz
Geneva Peace Week Vortrag 18.11.2015 Genève, Schweiz
2ème assemblée romande des collaborateurs/-trices de la Station Ornithologique Suisse à Yverdon Vortrag 11.11.2015 Yverdon, Schweiz
Café scientifique SCNAT à Lausanne Vortrag 17.09.2015 Lausanne, Schweiz
Controlling rodents with birds of prey for the environment and people Vortrag 18.06.2015 Nicosia, Zypern
Cercle de Sciences naturelle du Chablais à Aigle Vortrag 26.03.2015 Aigle, Schweiz
Formation avancée pour l’expérimentation sur des espèces animales sauvages CHUV Lausanne Vortrag 20.11.2014 Lausanne, Schweiz


Kommunikation mit der Öffentlichkeit

Kommunikation Titel Medien Ort Jahr
Referate/Veranstaltungen/Ausstellungen Société fribourgeoise des sciences naturelles Westschweiz 2016
Medienarbeit: Radio, Fernsehen Specimen rts Westschweiz 2016
Medienarbeit: Radio, Fernsehen La chouette effraie ne connaît pas de frontière rts la première Westschweiz 2015
Medienarbeit: Radio, Fernsehen Quand les poules avaient des dents radio suisse romande Westschweiz 2014

Verbundene Projekte

Nummer Titel Start Förderungsinstrument
135757 Sexually antagonistic selection: evidence and proximate mechanisms 01.07.2011 Projektförderung (Abt. I-III)
173178 The genomics of sexually antagonistic selection 01.07.2017 Projektförderung (Abt. I-III)
143353 Dialog rules to coordinate vocal signalling in an animal 01.12.2012 Projektförderung (Abt. I-III)
173178 The genomics of sexually antagonistic selection 01.07.2017 Projektförderung (Abt. I-III)
135757 Sexually antagonistic selection: evidence and proximate mechanisms 01.07.2011 Projektförderung (Abt. I-III)

Abstract

Establishing the links between phenotype and genotype is key to resolve questions about the evolution, maintenance and adaptive function of phenotypic variation. This is particularly interesting when a phenotype is positively selected in one sex but negatively in the other sex (sexually antagonistic selection). Identifying the genes responsible for variation in phenotypes selected in opposite direction in the two sexes is particularly interesting because these genes may have beneficial physiological effects in one sex but detrimental in the other sex. In the present project, we intend to tackle the genetic basis of sexually antagonistic selection exerted on a melanin-based plumage trait in the cosmopolitan barn owl. Owls display black spots on feather tips, a genetically inherited trait for which the expression is not sensitive to the environment and body condition. Although males and females can express any phenotype, males are on average smaller-spotted than females. Females displaying large black spots have a selective advantage over smaller-spotted male-like females (and the other way round in males). Because the melanocortin system is involved in the expression of melanin pigments and pleiotropically regulate a large number of physiological and behavioral traits, we hypothesized that genes of the melanocortin system are sexually antagonistically selected promoting the evolution of intralocus sexual genetic conflict. Because we are specifically interested in the melanocortin system, we will look for polymorphisms in this system as well as measure the expression levels of these genes in relation to melanin-based coloration and their associated traits. We plan a number of (experimental) studies to understand the evolutionary implications of the melanocortin system, a topic that had not been considered until we proposed that this system explains why melanin-based colorations covary with many phenotypic traits in a consistent way across vertebrates. This project performed at the local (Switzerland) and worldwide scales is of interest from both evolutionary and medical point of views. Indeed, melanin-based coloration is found in most animals including humans and the underlying genetic system (particularly the melanocortin system) is highly conserved and implicated in many physiological functions and diseases.
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